Phthaloyl chloride 对苯二甲酰氯

CAS 100-20-9 MFCD00000693

化学结构图

100-20-9
SMILES: O=C(Cl)c1ccc(C(=O)Cl)cc1

化学属性

Mol. FormulaC8H4Cl2O2
Mol. Weight203
Vapor Density7 (vs air)
Boiling Point266
Vapor Pressure0.02 mmHg ( 25 °C)
Melting Point81.0 to 84.0 deg-C
Flash Point180°(356°F)
TSCAYes
Solubility溶于水。
Density7.0
Stability对湿度敏感
Appearance flakes

别名和识别编码

Chemical NamePhthaloyl chloride
MDL NumberMFCD00000693
CAS Number100-20-9
Synonym {Chemicalbook} 對酞醯二氯 TCl Terephthaloyl Dichloride benzen 1 对苯二酰二氯 terephthalolyl chloride p-Phthaloyl dichloride Terephthalsäuredichlorid Terephthalic dichloride 4-苯二碳酰二氯 TEREPHTHALOYL DICHLORIDE terephthalicacidchloride 1,4-Benzoldicarbonsäuredichlorid TEREPHTHALIC ACID DICHLORIDE 对酞酰氯 1,4-Benzenedicarbonyl chloride 1,4-苯二碳酰二氯 {u 二氯化对苯二甲酰,对苯二酰氯,对苯二酰二氯,对酞酰氯, 1,4-苯二酰氯, 1,4-苯二碳酰二氯 p-Phthalyl dichloride Terephthalyl dichloride 对苯二甲酰氯, 98+% 4-苯二酰氯 Terephthalic acid chloride P-PHTHALOYL CHLORIDE
PubChem Substance ID87576041
EC Number202-829-5
Beilstein Registry Number9,844
Chemical Name Translation对苯二甲酰氯
Reaxys-RN607796
Wiswesser Line NotationGVR DVG
LabNetwork Molecule IDLN00193921
InChIInChI=1S/C8H4Cl2O2/c9-7(11)5-1-2-6(4-3-5)8(10)12/h1-4H
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • {uni_hamburg} no charge; carbocycle; aromatic; 6RingOnly; 6ring; carbonyl chloride; 1fragment
  • {SNA} Acid Halides, Building Blocks, Carbonyl Compounds, Chemical Synthesis, Organic Building Blocks

产品应用

  • 农药;医药;染料;颜料;紫外线吸收剂;交联剂的中间体。

相关文献及参考

  • Short: III/31a
  • Short: III/35E
  • Beilstein:9,844

安全信息

GHS Symbol
WGK Germany3
Hazard statements
  • H290 May be corrosive to metals 可能腐蚀金属。
  • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
  • H331 Toxic if inhaled 吸入中毒
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Precautionary statements
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P403+P233
  • P305+P351+P338+P310
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P301+P330+P331+P310
  • P303+P361+P353
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P304+P340+P310
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
  • P303+P361+P353+P310+P363
  • P390 Absorb spillage to prevent material damage. 吸收溢出物,防止重大损害。
  • P308+P311
  • P304+P340+P311
  • P405 Store locked up. 上锁保管。
  • P234 Keep only in original container. 只保留在原来的容器中。
  • P406 Store in corrosive resistant/… container with a resistant inner liner. 存放在耐腐蚀/具有耐性的内衬容器。
Signal word
RTECSWZ1797000
Safety Statements
Packing GroupII
UN Number 2928 2923
Risk Statements
Storage condition Moisture Sensitive 充氩保存 密封干燥保存。
Hazard Codes T C,T
Hazard Class8/6.1
Warnings 危化品目录(2015) 危险化学品
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York,
   Academic Press, Inc., 1969  Volume(issue)/page/year: -,475,1969

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 700 mg/m3/4H
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - lacrimation
   Lungs, Thorax, or Respiration - dyspnea
   Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: OTS0533726

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 950 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 49(12),35,1984

TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : >200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: OTS0533726

{ha

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 4122 mg/kg
SEX/DURATION            : male 26 week(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Paternal Effects - spermatogenesis (incl. genetic material,
   sperm morphology, motility, and count)
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 49(12),35,1984

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 4122 mg/kg
SEX/DURATION            : female 26 week(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Maternal Effects - menstrual cycle changes or disorders
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 49(12),35,1984

其他信息

  • MSDS 信息:对苯二甲酰氯(100-20-9).msds
  • 蒸气密度:7 (vs air)
  • 方法一:有氯化亚砜法、五氯化磷法、光气法、酸氯化法及酯氯化法等。1.氯化亚砜法是将对苯二甲酸与氯化亚砜混合,在80℃回流10-12h,再蒸出氯化亚砜,将所得粗品减压蒸馏而得成品。2.酸氯化法是将对苯二甲酸在三氯化磷存在下通入氯气。反应温度120-140℃,反应时间4-5h,转化率近于100%,产品纯度99%以上。三氯化磷在过程中生成三氯氧磷,可以回收利用。3.对二甲苯进行光催化氯化制得对二(三氯甲基)苯,再与对苯二甲酸加热回流进行酰氯化反应,再用固体碳酸钠调至碱性,滤除氯化钠后,将液体减压蒸馏,收集68-75℃(1.866kPa)馏分即得。
  • 蒸气压:0.02 mm Hg ( 25 °C)
  • Sigma Aldrich:100-20-9(sigmaaldrich)
  • 毒性分级:低毒
  • 急性毒性:口服-大鼠 LD50: 2500 毫克/公斤; 口服-小鼠 LD50: 2140 毫克/公斤
  • 可燃性危险特性:可燃; 遇水放出有毒氯化氢气体
  • Acros Organics:对苯二甲酰氯 Terephthaloyl chloride, 99+%(100-20-9)
  • 上游原料:三氯氧磷 --> 氯 --> 五氯化磷 --> 对二甲苯 --> 对苯二甲酸 --> 三氯化苄
  • 用途三:农药;医药;染料;颜料;紫外线吸收剂;交联剂的中间体。
  • 用途二:对苯二甲酰氯和间苯二甲酰氯有许多相似的用途,也是聚酰胺、聚酯等聚合物的原料。全芳香族聚酰胺纤维作为一种耐热性阻燃纤维,引起人们广泛关注。该品也用作农药、医药、染料、颜料、紫外线吸收剂、交联剂的中间体。
  • 对苯二甲酰氯价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 80103526 对苯二甲酰氯;二氯化对苯二甲酰; 对苯二酰氯; 对苯二酰二氯; 对酞酰氯; 1,4-苯二酰氯 100g 37.4元 2011/04/16 T0017 对苯二甲酰氯 Terephthaloyl Chloride 25G 180元 2011/04/16 T0017 对苯二甲酰氯 Terephthaloyl Chloride 500G 865元
  • 不溶于水,易溶于苯、甲苯、二甲苯、氯仿等有机溶剂,易吸水分解,易与醇发生反应成醋酸酰胺。有腐蚀性及催泪性。
  • 图谱信息:对苯二甲酰氯(100-20-9)红外图谱(IR2) 对苯二甲酰氯(100-20-9)质谱(MS) 对苯二甲酰氯(100-20-9)红外图谱(IR1) 对苯二甲酰氯(100-20-9)Raman光谱
  • 灭火剂:砂土、干粉、二氧化碳
  • MOL 文件:100-20-9.mol
  • TCI Shanghai:对苯二甲酰氯 Terephthaloyl Chloride,>;99.0%(GC)(T)(100-20-9)
  • 类别:腐蚀物品
  • Alfa Aesar:对苯二甲酰氯,98+% Terephthaloyl chloride, 99%(100-20-9)
  • 下游产品:对甲苯磺酰胺 --> 1,4-二[2-(4-甲基-5-苯基恶唑)]苯 --> 氯酞酸二甲酯
  • 海关编码:29173980
  • 外观性质:白色固体。
  • 储运特性:库房通风低温干燥; 与碱、氧化剂分开存放
  • 用途一:是合成特种纤维的单体,可作芳纶、锦纶增强剂,也可作有机合成原料
  • 敏感性:Moisture Sensitive

系列性分类