4-Vinylpyridine 4-乙烯基吡啶

CAS 100-43-6 MFCD00006447

化学结构图

100-43-6
SMILES: C=Cc1ccncc1

化学属性

Mol. FormulaC7H7N
Mol. Weight105.14
Density0.975
Refractive indexn20/D 1.549(lit.)
Boiling Point62-65
Flash Point56°C(lit.)
TSCAYes
Solubility微溶于水、乙醚,溶于热水热乙醇。
Stability对热、光及空气敏感

别名和识别编码

Chemical Name4-Vinylpyridine
MDL NumberMFCD00006447
CAS Number100-43-6
EC Number202-852-0
Beilstein Registry Number104506
Synonym {uni_hamburg} 4-Pyridylethylene 4-乙烯基氮苯 4-ethenyl-pyridin 4-ethenylpyridine γ-Vinylpyridine 4-Ethenylpyridine 4-乙烯基吡啶 4-vinyl-pyridin 4-Vinylpyridine, stabilized, 95% 4-Vinylpyridine, stabilized, 95+% 4-Vinylpyridine monomer 4-Vinylpyridine, 95%, stabilized (4-Pyridyl)-ethylen 4-Vinylpyridine, 96%, stab. with 100ppm hydroquinone gamma-Vinylpyridine 4VP 4-乙烯基氮笨 4-Vinylpyridine (stabilized with TBC) gamma-vinylpyridine 4-乙烯基吡啶, 96%, 100PPM氢醌作稳定剂 Pyridine,4-ethenyl- 4-Vinylpyridine 4-吡啶基乙烯 Pyridine, 4-vinyl- 4-Ethenyl-pyridin 4-乙烯基氮苯; 4-乙烯吡啶 4-vinylpyridine 4-vinyl-pyridine 4-乙呲啶 1-(4-Pyridinyl)ethene 4-vinylpyridine monomer 4-VINYLPYRIDINE Vinylpyridine,4- Pyridine, 4-ethenyl-
PubChem Substance ID7502
Chemical Name Translation4-乙烯基吡啶
Reaxys-RN104506
LabNetwork Molecule IDLN00193285
InChIInChI=1S/C7H7N/c1-2-7-3-5-8-6-4-7/h2-6H,1H2
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分类

  • {uni_hamburg} no charge; nitrogen heterocycle; aromatic; 6RingOnly; 6ring; 1fragment
  • {SNA} Materials Science, Monomers, Polymer Science, Vinyl Halides, Amines, Amides, and Other Vinyl Monomers
  • {SNA} Monomers, Polymer Science, Vinyl Halides, Amines, Amides, and Other Vinyl Monomers, 材料科学

产品应用

  • 用作有机合成中间体和聚合物的单体。应用于功能性高分子、表面活性剂、抗静电剂、感光性树脂、涂料、医药、农药等许多方面。

相关文献及参考

  • In the presence of NaOEt, thiols are protected as their S-2-(4-pyridyl)ethyl thioethers: J. Org. Chem., 51, 4914 (1986). Cleavage can be effected by methylation-hydrolysis: Tetrahedron Lett ., 25, 1223 (1984). Compare also 4-(2-Hydroxyethyl)­pyridine, L13780.
  • Short: II/14a
  • Short: III/38B
  • Beilstein:20(2)170
  • Short: EINECS
  • Short: IV/6
  • Short: IV/18B

安全信息

Signal word Danger
GHS Symbol
WGK Germany3
Safety Statements
  • S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
  • S22 Do not breathe dust 不要吸入粉尘;
  • S23 Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) 不要吸入气体/烟雾/蒸汽/喷雾;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后,立即用大量…(由生产厂家指定)冲洗;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
  • S9 Keep container in a well-ventilated place 保持容器在通风良好的场所;
Risk Statements
  • R10 Flammable 易燃
  • R20 Harmful by inhalation 吸入有害
  • R25 Toxic if swallowed 吞咽有毒
  • R34 Causes burns 会导致灼伤
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R42/43
Precautionary statements
  • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P284 Wear respiratory protection.? 佩戴呼吸保护装置。
  • P301+P310
  • P301+P330+P331+P310
  • P303+P361+P353
  • P305+P351+P338
  • P305+P351+P338+P310
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P403+P233
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
RTECSUU1045000
Packing GroupII
UN Number 3073 UN 3073 6.1/PG 2
Hazard Codes 6.1 T
Hazard statements
  • H226 Flammable liquid and vapour 易燃液体和蒸气
  • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
  • H317 May cause an allergic skin reaction 可能导致皮肤过敏
  • H301 Toxic if swallowed 吞食有毒
Personal Protective Equipment Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Storage condition -20°C 0-10 -20℃保存 0-10°C 储存温度-20°C,充氩储存
Hazard Class6.1/3, 8
Warnings 危化品目录(2015)
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 161 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - aggression
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 28(6),55,1984

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 321 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - aggression
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 28(6),55,1984

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
   Prague, Czechoslovakia, Avicenum, 1986  Volume(issue)/page/year: -,845,1986

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 170 mg/m3
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GISAAA Gigiena

Restrict 危险品

其他信息

  • 上游原料:氢氧化钠 --> 氢氧化钾 --> 甲醛 --> 酸性氧化铝 --> 1,4-苯二酚 --> 叔丁醇钾 --> 硝酸钾 --> 硝酸钠 --> 乙酸钾 --> 2-氨基苯酚 --> 4-甲基吡啶 --> 磷酸钾 --> 4-乙醇基吡啶 --> 对叔丁基邻苯二酚 --> 碱性亚甲蓝三水合物 --> 硝酸铷
  • 用途一:用作有机合成中间体和聚合物的单体。应用于功能性高分子、表面活性剂、抗静电剂、感光性树脂、涂料、医药、农药等许多方面。
  • 无色至黄色液体。在100g20℃的水中可溶解2.9g、水在100g该品中可溶解42.3g,溶于甲醇、乙醚、苯、丙酮,微溶于醚。遇光、受热发生聚合,贮存时常加0.1%-0.2%的对苯二酚作为阻聚剂。
  • Alfa Aesar:4-乙烯基吡啶,96%,100ppm氢醌作稳定剂 4-Vinylpyridine, 96%, stab. with 100ppm hydroquinone(100-43-6)
  • 灭火剂:干粉、二氧化碳、砂土、泡沫
  • 类别:有毒物品
  • Acros Organics:4-乙烯基吡啶 4-Vinylpyridine, stabilized, 95%(100-43-6)
  • 方法一:由4-甲基吡啶与甲醛反应生成4-吡啶乙醇,然后脱水而得。
  • MOL 文件:100-43-6.mol
  • 外观性质:无色液体。
  • 储运特性:库房通风低温干燥; 与食品原料分开储运
  • 在100g20℃的水中可溶解2.9g、水在100g该品中可溶解42.3g,溶于甲醇、乙醚、苯、丙酮,微溶于醚。遇光、受热发生聚合,贮存时常加0.1%-0.2%的对苯二酚作为阻聚剂。
  • Sigma Aldrich:100-43-6(sigmaaldrich)
  • 可燃性危险特性:明火可燃; 受热分解有毒氧化氮气体
  • 下游产品:4-吡啶乙硫醇盐酸盐
  • MSDS 信息:4-乙烯基吡啶(100-43-6).msds
  • 4-乙烯基吡啶价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 L1331602 4-乙烯基吡啶,96% 100ml 310元 2011/04/16 V0025 4-乙烯基吡啶(含稳定剂TBC) 4-Vinylpyridine (stabilized with TBC) 25ML 289元 2011/04/16 V0025 4-乙烯基吡啶(含稳定剂TBC) 4-Vinylpyridine (stabilized with TBC) 500ML 2549元
  • 图谱信息:4-乙烯基吡啶(100-43-6)核磁图( 13 CNMR) 4-乙烯基吡啶(100-43-6)红外图谱(IR2) 4-乙烯基吡啶(100-43-6)红外图谱(IR1) 4-乙烯基吡啶(100-43-6)质谱(MS) 4-乙烯基吡啶(100-43-6)核磁图( 1 HNMR)
  • 毒性分级:高毒
  • 急性毒性:口服-大鼠 LD50: 100 毫克/公斤; 口服-小鼠 LD50: 161 毫克/公斤
  • F:8-10
  • TCI Shanghai:4-乙烯基吡啶(含稳定剂叔丁基邻苯二酚) 4-Vinylpyridine (stabilized with TBC),>;95.0%(GC)(100-43-6)

系列性分类


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