Vinyl acetate 乙酸乙烯酯

CAS 108-05-4 MFCD00008713

化学结构图

108-05-4
SMILES: C=COC(C)=O

化学属性

Mol. FormulaC4H6O2
Mol. Weight86
Refractive index1.3920 to 1.3990
Boiling Point72-73
Density0.934
Melting Point-93
Flash Point-8°C(lit.)
TSCAYes
Autoignition Point801 °F
Vapor Density3 (vs air)
Vapor Pressure88 mmHg ( 20 °C)
Solubility微溶于水，溶于醇、醚、丙酮、苯、氯仿。
Stability对光敏感

别名和识别编码

Chemical NameVinyl acetate
Synonym 1-Acetoxyethylene ACETIC ACID VINYL ESTER ACETIC ACID VINYL ESTER MONOMER Ace Acetic acid vinyl ester Acetoxyethene Acetoxyethylene CH3CO2CH=CH2 Essigsäureethenylester Ethanoic acid vinyl ester Ethanoic acid, ethenyl ester VAC VAM VINYL ACETATE Vinyl A monomer Vinyl acetate Vinyl acetate monomer Vinylester kyseliny octove VyAc Zeset T acetic acid vinyl ester acetoxyethene 乙烯基乙酸酯 乙烯基醋酸酯 乙酸乙烯单体 乙酸乙烯酯 醋酸乙烯,乙酸乙烯,乙烯基乙酸酯,醋酸乙烯酯 醋酸乙烯单体 醋酸乙烯酯, 99%, STAB. WITH 8-12PPM HYDROQUINONE 醋酸乙烯酯/乙酸乙烯酯
CAS Number108-05-4
PubChem Substance ID7904
EC Number203-545-4
Beilstein Registry Number1209327
MDL NumberMFCD00008713
Reaxys-RN1209327
Merck Number9992
Chemical Name Translation乙酸乙烯酯
Wiswesser Line Notation1VO1U1
LabNetwork Molecule IDLN00195778
InChIInChI=1S/C4H6O2/c1-3-6-4(2)5/h3H,1H2,2H3
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分类

  • {SA} Building Blocks, C2 to C5,
  • {SNA} Building Blocks, C2 to C5, Carbonyl Compounds, Chemical Synthesis, Esters, Monomers, Organic Building Blocks, Polymer Science, Vinyl Esters, 材料科学
  • {SNA} Building Blocks, C2 to C
  • {SNA} Analytical Standards,
  • 8000 Series Solidwaste Methods, Alpha Sort, Alphabetic, Analytical Standards, Analytical/Chromatography, Chemical Class,
  • {SNA} Analytical Standards, Chromatography, EP Standards, EP Standards U - Z, Pharmaceutical Standards, Pharmacopeia Standards, 分析/色谱
  • {uni_hamburg} no charge; ester; 1fragment

产品应用

  • 用于有机合成

相关文献及参考

  • {
  • For example of mercuric acetate-catalyzed transesterification to long-chain vinyl esters, see: Org. Synth. Coll., 4, 977 (1963).
  • Merck:14,9992
  • Merck:14,9992 Beilstein:2(4)176
  • Short: II/27B
  • For thermal [2+2] cycloaddition with chlorotrifluoroethylene, see: Org. Synth. Coll., 5, 235 (1973); and with chlorosulfonyl isocyanate to give a ß-lactam: Org. Synth. Coll., 8, 3 (1993).

安全信息

GHS Symbol
WGK Germany2
Hazard Codes 3
Hazard statements
  • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
  • H332 Harmful if inhaled 吸入有害
  • H351 Suspected of causing cancer 怀疑致癌
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H412 Harmfutoaquaticlifewithlonglastingeffects 对水生生物有害并具有长期影响。
Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
RTECSAK0875000
Precautionary statements
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
  • P302+P352+P333+P313+P362+P364
  • P303+P361+P353
  • P304+P340
  • P304+P340+P312
  • P305+P351+P338
  • P308+P313
  • P337+P313
  • P403+P233
  • P403+P235
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Signal word Danger
Safety Statements
  • S16 Keep away from sources of ignition - No smoking 远离火源，禁止吸烟；
  • S23 Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) 不要吸入气体/烟雾/蒸汽/喷雾；
  • S29 Do not empty into drains 不要排入下水道；
  • S33 Take precautionary measures against static discharges 对静电采取预防措施；
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
  • S7 Keep container tightly closed 保存在严格密闭容器中；
Risk Statements
  • R11 Highly flammable 非常易燃
UN Number 1301
Packing GroupII
Storage condition 密封阴凉避光保存。 储存温度2-8℃ 密封阴凉避光保存。储存温度2-8°C 0-6°C
Hazard Class3
Warnings 危化品目录(2015) 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 100 gm/kg/2Y-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Endocrine - thyroid tumors
   Reproductive - Tumorigenic effects - uterine tumors
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   68,43,1983

TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 600 ppm/6H/5D/2Y-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Sense Organs and Special Senses (Olfaction) - tumors
REFERENCE :
   EPASR* United States Environmental Protection Agency, Office of Pesticides
   and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW,
   Washington, DC 20460)  History unknown.  Volume(issue)/page/year:
   8EHQ-0187-0650

TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 600 ppm/6H/5D/2Y-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
REFERENCE :
   EPASR* United States Environmental Protection Agency, Office of Pesticides
   and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW,
   Washington, DC 20460)  History unknown.  Volume(issue)/page/year:
   8EHQ-0187-0650

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 2335 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DUPON* E.I. Dupont de Nemours and Company, Technical Sheet.  (1007 Market
   St., Wilmington, DE 19898)  Volume(issue)/page/year: ES-3574,1975

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 2500 ppm/4H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85INA8 "Documentation of the Threshold Limit Values and Biological Exposure
   Indices," 5th ed., Cincinnati, OH, American Conference of

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 11400 mg/m3/4H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 25(11),57,1981

TYPE OF TEST            : LC50 - Lethal concen

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 2500 ppm/4H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85INA8 "Documentation of the Threshold Limit Values and Biological Exposure
   Indices," 5th ed., Cincinnati, OH, American

TYPE OF TEST

{haz

{hazard_c

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 125 umol/L
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   45,4816,1985

TYPE OF TEST            : Morphological transformation
TEST SYSTEM             : Rodent - hamster Embryo
DOSE/DURATION           : 62500 ug/L
REFERENCE :
   AETODY Advances in Modern Environmental Toxicology.  (Senate Press, Inc.,
   P.O. Box 252, Princeton Junction, NJ 08550)  V.1-    1980-
   Volume(issue)/page/year: 1,241,1980

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 100 umol/L
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   45,48

TYPE OF TEST            : Micronucleus test
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 500 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 190,41,1987

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 250 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 159,109,1986

TYPE OF TEST            : Sperm Morphology
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 2500 mg/kg/5D
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 202,171,1988

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 91 gm/kg
SEX/DURATION            : multigeneration
TOXIC EFFECTS :
   Reproductive - Maternal Effects - other effects
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
REFERENCE :
   FAATDF Fundamental and Applied Toxicology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1981-  Volume(issue)/page/year:
   24,206,1995

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 500 mg/kg/D
SEX/DURATION            : multigenerations
TOXIC EFFECTS :
   Reproductive - Fertility - male fertility index (e.g. # males impregnating
   females per # males exposed to fertile nonpregnant females)
REFERENCE :
   EPASR* United States Environmental Protection Agency, Office of Pesticides
   and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW,
   Washington, DC 20460)  History unknown.  Volume(issue)/page/year:
   8EHQ-0185-0543

TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 1000 ppm/6H
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Maternal Effects - other effects
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
   FAATDF Fundamental and Applied Toxicology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1981-  Volume(issue)/page/year:
   24,198,1995

Restrict 危险品

其他信息

  • MSDS 信息:乙酸乙烯酯(108-05-4).msds
  • TCI Shanghai:乙酸乙烯酯单体(含稳定剂氢醌) Vinyl Acetate Monomer (stabilized with HQ),>;99.0%(GC)(108-05-4)
  • 外观性质:无色液体, 具有
  • 用途三:乙酸乙烯是制造合成纤维维尼纶的主要原料。乙酸乙烯通过自身聚合，或者与分单体共聚，得到聚乙烯醇、乙酸乙烯-乙烯共聚合物（EVA）、乙酸乙烯-氯乙烯共聚物（EVC）、乙酸乙烯-丙烯腈类纤维、乙酸乙烯-丙烯酸酯类共聚物，它们都有重要的工业用途，广泛用作粘结剂、建筑涂料、纺织品上浆剂和整理剂、纸张增强剂，以及用于制造安全玻璃等。乙酸乙烯酯与乙醇、溴素反应制得溴代乙醛缩二乙醇。这是药物甲硫咪唑的中间体。
  • 蒸气压:88 mm Hg ( 20 °C)
  • MOL 文件:108-05-4.mol
  • 下游产品:聚乙烯醇 --> 2-溴-1,1-二乙氧基乙烷 --> (-)-文斯内酯 --> 他唑巴坦酸 --> alpa-乙酰基-gama-丁酯 --> (2-甲氧基乙氧基)乙醛缩二甲醇 --> 2-三氟甲基-喹啉-7-羧酸 --> 聚醋酸乙烯酯 --> 无纺布胶 --> 855 化纤布挺括剂 --> 硬脂酸酯乙烯基 --> 压敏胶 --> 棕榈酸乙烯酯 --> 乙酰化二淀粉磷酸酯(乙酰化磷酸双淀粉) --> LT-01 乳胶 --> PR-I复鞣剂 --> 马来酸-醋酸乙烯酯共聚物 --> 辐射引发淀粉接枝醋酸乙烯酯吸水剂 --> 乙酰化磷酸双淀粉 --> PC 系列纸品乳液 --> 2-甲基丙烯酸与乙烯的聚合物 --> 醋丙乳液 --> 淀粉乙酸酯 --> SSS-85 型粘合剂 --> 5-降冰烯-2-基乙酸酯 --> 乙烯-醋酸乙烯共聚物
  • Acros Organics:乙酸乙烯酯 Vinyl
  • 乙酸乙烯酯价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 80138618 乙酸乙烯酯（怕热） 500ml 31元 2011/08/23 80138628 乙酸乙烯酯（怕热） 500ml 29元 2011/04/16 A0045 醋酸乙烯酯单体(含稳定剂HQ) Vinyl Acetate Monomer (stabilized with HQ) 500ML 220元
  • 防护措施:醋酸乙烯酯毒性低，大鼠经口LD50为2920mg/kg。有麻醉性和刺激作用，高浓度蒸气可引起鼻腔发炎、眼睛出现红点。皮肤长期接触有产生皮炎的可能。 操作场所保持良好通风，操作人员应配备防护装具。皮肤接触后，立即用肥皂和水洗净并涂抹润肤剂。
  • 用途二:用于树脂纤维合成，也用作油类降凝增稠剂的中间体和粘合剂
  • Sigma Aldrich:108-05-4(sigmaaldrich)
  • 无色液体，具有甜的醚味。易受热、光或微量过氧化物的作用聚合成透明固体。微溶于水，溶于醇、醇、丙酮、苯、氯仿，20时水中溶解度为1g/50ml。有刺激性。
  • 海关编码:29333999
  • 用途一:用于生产聚乙烯醇、涂料及粘合剂等
  • 方法一:有乙炔法、乙烯法、乙醛醋酐等几种不同原料的工艺路线。乙烯原料路线按工艺不同又有乙烯气相法、乙烯液相法等不同方法。1.乙炔法以载于活性炭上的醋酸锌为催化剂，乙炔与醋酸在常压及170-230℃下反应。反应产物经粉末分离、气体分离、除醛、粗馏、精馏得精醋酸乙烯酯。2.乙烯气相法乙烯、氧气和醋酸在钯-金（或铂）催化剂存在下，于160－180℃，＜1MPa压力条件下气相反应生成醋酸乙烯酯，再经分离、精馏得精品。3.乙烯液相法乙烯、醋酸以氯化钯-氯化铜为催化剂反应得醋酸乙烯酯。4.乙醛醋酐法以乙醛醋酐为原料，先合成亚乙基二醋酸，再经脱醋酸反应，由一步法或两步法合成。
  • 上游原料:乙酸 --> 氯化钯 --> 乙炔 --> 铂
  • 图谱信息:乙酸乙烯酯(108-05-4)质谱(MS) 乙酸乙烯酯(108-05-4)红外图谱(IR2) 乙酸乙烯酯(108-05-4)核磁图( 13 CNMR) 乙酸乙烯酯(108-05-4)Raman光谱 乙酸乙烯酯(1

系列性分类

  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Alphabetic - Analytical Standards
  4. V - Alphabetic
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Organic Building Blocks 有机砌块
  4. Carbonyl Compounds 羰基化合物
  5. Esters - Carbonyl Compounds
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Organic Building Blocks 有机砌块
  4. Carbonyl Compounds 羰基化合物
  5. Esters - Carbonyl Compounds
  6. C2 to C5 - Esters
  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Alphabetic - Analytical Standards
  4. A - Alphabetic
  5. AM to AQ - A
  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Method Specific - Analytical Standards
  4. NIOSH and OSHA Methods - Method Specific
  5. OSHA 51: Analysis of Vinyl Acetate in Indoor Air - NIOSH and OSHA Methods
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Monomers
  4. Styrene and Functionalized Styrene Monomers
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Organic Building Blocks 有机砌块
  4. Carbonyl Compounds 羰基化合物
  5. Esters
  6. C12 to C63