M-Xylene 间二甲苯(易涉毒)

CAS 108-38-3 MFCD00008536

化学结构图

108-38-3
SMILES: CC1=CC(C)=CC=C1

化学属性

Mol. FormulaC8H10
Mol. Weight106
Refractive index1.4950 to 1.4980
Boiling Point139
Density0.864
Melting Point-48
Flash Point28°C(lit.)
TSCAYes
Autoignition Point982 °F
Vapor Density3.7 (vs air)
Vapor Pressure16 mmHg ( 37.7 °C)
Solubility不溶于水,可混溶于乙醇、乙醚、氯仿等多数有机溶剂。
Stability对光敏感

别名和识别编码

Chemical NameM-Xylene
Synonym m-Dimethylbenzol 1,3-dimethylbenzene M-METHYLTOLUENE M-XYLENE OEKANAL 间二甲苯标准溶液 M-XYLENE, REAGENTPLUS, 99% 1,3-二甲基苯;1,3-二甲苯 M-XYLENE, 1X1ML, MEOH, 200UG/ML M-XYLENE DISTILLED 1 L m-xylene [srp]m-methyltoluene {Chemi 1,3-dimethyl-benzene 间二甲苯标准溶液;1,3-二甲基苯;1,3-二甲苯 1,3-二甲苯,间二甲苯 1,3-Xylene 3-xylene 1,3-DIMETHYLBENZENE m-Methyltoluene 1,3-Dimethylbenzol 1,3-Xylene META-XYLENE m-Xylol M-xylene μ-Xylene m-Dimethylbenzene 1,3-dimethyl-benzen Benzene,1,3-dimethyl- 间二甲苯 be
CAS Number108-38-3
PubChem Substance ID87577880
EC Number203-576-3
Beilstein Registry Number605441
MDL NumberMFCD00008536
Reaxys-RN605441
Merck Number10081
Chemical Name Translation间二甲苯(易涉毒)
Wiswesser Line Notation1R C1
LabNetwork Molecule IDLN00163553
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分类

  • {Chemicalbook} 农药中间体: 杀菌剂中间体: 芳香族苯类杀菌剂
  • {uni_hamburg} no charge; carbocycle; aromatic; 6RingOnly; 6ring; 1fragment
  • Analytical Reagents, Analytical Reagents for General Use, Analytical/Chromatography, Carthamus tinctorius (Safflower oil), Nutrition Research, Panax ginseng, Phytochemicals by Plant (Food/Spice/Herb), Puriss p.a., T-Z, Puriss p.a.
  • {SNA} Analytical Standards, Analytic

产品应用

  • 溶剂。有机合成。测定矿物的折光率。气相色谱分析标准。清洗剂。

相关文献及参考

  • Short: II/27B
  • Merck:14,10081 Beilstein: 5,IV,932
  • Short: II/2
  • Merck:14,10081

安全信息

GHS Symbol
WGK Germany2
Hazard Codes 3
Hazard statements
  • H226 Flammable liquid and vapour 易燃液体和蒸气
  • H312+H332
  • H315 Causes skin irritation 会刺激皮肤
  • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
  • H304 May be fatal if swallowed and enters airways 吞食和进入呼吸道可能致命
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H412 Harmfutoaquaticlifewithlonglastingeffects 对水生生物有害并具有长期影响。
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H332 Harmful if inhaled 吸入有害
  • H312 Harmful in contact with skin 皮肤接触有害
Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
RTECSZE2275000
Precautionary statements
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
  • P241+P242+P243
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P310
  • P302+P352+P332+P313+P362+P364
  • P303+P361+P353
  • P304+P340+P312
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P308+P311
  • P331 Do NOT induce vomiting.. 不要催吐。
  • P332+P313
  • P337+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P370+P378
  • P403+P233
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Signal word Danger Warning
UN Number 1307 UN1307
Risk Statements
  • R10 Flammable 易燃
  • R20/21 Harmful by inhalation and in contact with skin 吸入及与皮肤接触有害
  • R38 Irritating to skin 刺激皮肤
Safety Statements
  • S25 Avoid contact with eyes 避免眼睛接触;
Packing GroupIII
Hazard Class3
Storage condition 密封阴凉保存。 储存温度2-8℃ 0-6°C
Warnings 危化品目录(2015)
TYPE OF TEST            : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 8000 ppm/4H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIHAAP American Industrial Hygiene Association Journal.  (AIHA, 475 Wolf
   Ledges Pkwy., Akron, OH 44311)  V.19-    1958-  Volume(issue)/page/year:
   23,95,1962

{h

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 14100 uL/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIHAAP American Industrial Hygiene Association Journal.  (AIHA, 475 Wolf
   Ledges Pkwy., Akron, OH 44311)  V.19-    1958-  Volume(issue)/page/year:
   23,95,1962

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 5 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YAKUD5 Gekkan Yakuji.  Pharmaceuticals Monthly.  (Yakugyo Jihosha, Inaoka
   Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan)  V.1-   1959-
   Volume(issue)/page/year: 22,883,1980

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2003 uL/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARTODN Archives of Toxicology.  (Springer-Verlag, Heidelberger Pl. 3, D-1000
   Berlin 33, Fed. Rep. Ger.)  V.32-    1974-  Volume(issue)/page/year:
   58,106,1985

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPO

TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 500 mg/m3/12H
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
   ATSUDG Archives of Toxicology, Supplement.  (Springer-Verlag New York, Inc.,
   Service Center, 44 Hartz Way, Secaucus, NJ 07094)  No.1-    1978-
   Volume(issue)/page/year: 8,425,1985

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 30 mg/kg
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured
   before birth)
REFERENCE :
   APTOD9 Abstracts of Papers, Society of Toxicology.  Annual Meetings.
   (Academic Press, Inc., 1 E. First St., Duluth, MN 55802)
   Volume(issue)/page/year: 19,A22,1980

TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rabbit
DOSE                    : 500 mg/m3/24H
SEX/DURATION            : female 7-20 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
   Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
   ATSUDG Archives of Toxicology, Supplement.  (Springer-Verlag New York, Inc.,
   Service Center, 44 Hartz Way, Secaucus, NJ 07094)  No.1-    1978-
   Volume(issue)/page/year: 8,425,1985

TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSU

Restrict 危险品

其他信息

  • 方法一:其制备方法是利用石油二甲苯或煤焦油二甲苯进行分离,分离的方法可以用低温结晶法、配合法、吸附法和磺化水解法等。国内过去用磺化水解法生产间二甲苯,现在已采用吸附法分离间二甲苯。吸附法用分子筛为吸附剂,可以进行气相吸附,也可以进行液相吸附,其工艺分述如下。 (1)磺化水解法 将混合二甲苯经精馏切取130~140℃馏分,再加硫酸磺化,反应温度80~90℃,反应时间3.5h,然后分出磺化二甲苯,再经水解、蒸馏,切取140~150℃馏分而得成品。 该方法对设备腐蚀严重,并有较多的三废,仅能小规模生产,因此被吸附法所取代。 (2)吸附法 采用分子筛进行液相吸附或气相吸附,液相吸附以K-Ba-Y型为吸附剂,甲苯为解吸剂,在移动床进行连续吸附分离,操作温度65~85℃,吸附剂与原料比不大于10,脱附剂与原料比大于5。气相吸附也采用K-Ba-Y型分子筛为吸附剂,吸附温度170~180℃,操作压力为常压。吸附分离法是近代分离二甲苯的新方法。
  • 毒性分级:中毒
  • 方法二:1.将混合二甲苯精馏,切取130-140℃馏分,再加硫酸磺化,反应温度80-90℃,反应3.5h,然后分出未磺化的二甲苯,再经水解、蒸馏,切取140-150℃馏分而得成品。2.原料甲苯在烷基转移反应器中,进行烷基转移反应,生成二甲苯和苯。混合二甲苯在
  • TCI Shanghai:间二甲苯(1mg/ml的甲醇溶液)[用于水分析] m-Xylene (1mg/ml in Methanol) [for Water Analysis](108-38-3)
  • 刺激数据:皮肤- 兔子 20 毫克/24 小时 中度; 眼睛- 兔子 5 毫克/ 24小时 轻度
  • 蒸气压:16 mm Hg ( 37.7 °C)
  • 职业标准:TWA 435 毫克/ 立方米
  • 储运特性:库房通风低温干燥; 与氧化剂分开存放
  • 类别:较易燃液体
  • 用途二:用作分析试剂和精密光学仪器的溶剂和清洗剂,也用于有机合成
  • 蒸气密度:3.7 (vs air)
  • 方法一:其制备方法是利用石油二甲苯或煤焦油二甲苯进行分离,分离的方法可以用低温结晶法、配合法、吸附法和磺化
  • 灭火剂:干粉、干砂、二氧化碳、泡沫、1211灭火剂
  • 爆炸物危险特性:与空气混合可爆
  • {Chemicalb
  • 用途四:主要作溶剂,用于生产间苯二甲酸进而生产不饱和聚酯树脂和涂料,还用于生产间甲基苯甲酸、间苯二甲腈,医药利多卡因、氧甲唑啉,新泛影等。还可用于香料、彩色电影胶片的油溶性成色剂等的原料和染料中间体。由于生产间二甲苯的技术难度大,我国产量很少,无论产量还是质量都不能满足市场需要。
  • 用途五:溶剂。有机合成。测定矿物的折光率。气相色谱分析标准。清洗剂。
  • 无色透明液体。能与醇、醚和其他许多有机溶剂混和,不溶于水。能燃烧。低毒,半数致死量(大鼠,经口)4000mg/kg。有刺激性。
  • 图谱信息:间二甲苯(108-38-3)红外图谱(IR1) 间二甲苯(108-38-3)核磁图( 13 CNMR) 间二甲苯(108-38-3)Raman光谱 间二甲苯(108-38-3)质谱(MS) 间二甲苯(108-38-3)核磁图( 1 HNMR)
  • 下游产品:对二甲苯 --> 1,2-二甲苯 --> 2,6-二甲基苯胺 --> 甲霜灵 --> 间苯二甲酸 --> 双甲眯 --> 4-溴-3-甲基苄胺 --> 百菌清 --> 均苯四甲酸二酐 --> 1,2,4,5-四甲苯 --> 间苯二甲腈 --> 间甲基苯甲酸 --> 2,4-二甲基苯胺 --> 二甲苯麝香 --> N-(2,4-二甲苯基)-N'-甲基甲脒盐酸盐 --> 1,4-双(三氯甲基)苯 --> 对氯苯氧乙酸二甲胺基乙酯 --> 酮麝香 --> 1,3-二甲基-4-硝基苯 --> 5-叔丁基-苯乙烯 --> 2,6-二氰基-4-硝基苯胺 --> 2,6-二甲基硝基苯 --> 3,
  • 外观性质:无色透明液体,有类似甲苯的气味。
  • 间二甲苯价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011

系列性分类


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