Imidazo(4,5-d)(1,3)diazepin-8-ol,3,4,7,8-tetrahydro-3-beta-D-ribofuranosyl-, (R)-

CAS 11033-22-0 MFCD00036884

化学结构图

11033-22-0
SMILES: OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2C(O)CNC=NC1=2

化学属性

Mol. FormulaC11H16N4O5
Mol. Weight284.31

别名和识别编码

Chemical NameImidazo(4,5-d)(1,3)diazepin-8-ol,3,4,7,8-tetrahydro-3-beta-D-ribofuranosyl-, (R)-
Synonym Coformycin (R)-3,4,7,8-Tetrahydro-3-beta-D-ribofuranosylimidazo(4,5-d)(1,3)diazepin-8-ol
CAS Number11033-22-0
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相关文献及参考

  • [2]. Lukey T, et al. S-adenosylhomocysteine hydrolase activity, deoxyadenosine triphosphate accumulation, and competence of thymocyte and spleen leucocyte response to mitogens in coformycin-treated mice. Biochem Pharmacol. 1983 Apr 15;32(8):1399-406.
  • [1]. Coformycin.
  • [1]. Coformycin.
  • [2]. Lukey T, et al. S-adenosylhomocysteine hydrolase activity, deoxyadenosine triphosphate accumulation, and competence of thymocyte and spleen leucocyte response to mitogens in coformycin-treated mice. Biochem Pharmacol. 1983 Apr 15;32(8):1399-406.

安全信息

RTECSNI2931500 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 35 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- ,  Berdy, J., Boca
   Raton, FL, CRC Press, 1980-  Volume(issue)/page/year: 5,330,1981

系列性分类

  1. Medical Research Areas
  2. Metabolism
  3. Adenosine Deaminase  (腺苷脱氨酶)

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