3-(5-(4-(1H-Imidazol-1-Yl)Phenyl)-1-(4-Carbamoyl-2-Methylphenyl)-1H-Pyrrol-2-Yl)Propanoic Acid 3-(5-(4-(1H-咪唑-1-基)苯基)-1-(4-氨基甲酰基-2-甲基苯基)-1H-吡咯-2-基)丙酸

CAS 1208315-24-5 MFCD308315245

化学结构图

1208315-24-5
SMILES: Cc1cc(C(N)=O)ccc1-n1c(CCC(=O)O)ccc1-c1ccc(-n2ccnc2)cc1

化学属性

Mol. Weight414.46
Appearance white to off-white solid powder
SolubilitySoluble in DMSO, not in water

别名和识别编码

Chemical Name Translation3-(5-(4-(1H-咪唑-1-基)苯基)-1-(4-氨基甲酰基-2-甲基苯基)-1H-吡咯-2-基)丙酸
Chemical Name3-(5-(4-(1H-Imidazol-1-Yl)Phenyl)-1-(4-Carbamoyl-2-Methylphenyl)-1H-Pyrrol-2-Yl)Propanoic Acid
FormulaC24H22N4O3
Synonym N6022; N-6022; N 6022.
IUPAC Name3-(5-(4-(1H-imidazol-1-yl)phenyl)-1-(4-carbamoyl-2-methylphenyl)-1H-pyrrol-2-yl)propanoic acid
InChIKeyYVPGZQLRPAGKLA-UHFFFAOYSA-N
InChIInChI=1S/C24H22N4O3/c1-16-14-18(24(25)31)4-9-21(16)28-20(8-11-23(29)30)7-10-22(28)17-2-5-19(6-3-17)27-13-12-26-15-27/h2-7,9-10,12-15H,8,11H2,1H3,(H2,25,31)(H,29,30)
Canonical SMILESO=C(O)CCC1=CC=C(C2=CC=C(N3C=CN=C3)C=C2)N1C4=CC=C(C(N)=O)C=C4C
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

产品应用

  • N6022 is a potent, selective, reversible, and efficacious S-nitrosoglutathione reductase (GSNOR) inhibitor and is currently undergoing clinical development for the treatment of acute asthma. GSNOR is a member of the alcohol dehydrogenase family (ADH) and regulates the levels of S-nitrosothiols (SNOs) through catabolism of S-nitrosoglutathione (GSNO).

安全信息

Storage condition Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

系列性分类

  1. Medical Research Areas
  2. Metabolism
  3. Dehydrogenase

相关产品推荐