Deltorphin II 德尔托啡肽II

CAS 122752-16-3 MFCD00080072

化学结构图

122752-16-3
SMILES: C[C@@H](NC(=O)[C@@H](N)CC1C=CC(O)=CC=1)C(=O)N[C@@H](CC1C=CC=CC=1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)NCC(N)=O

化学属性

Mol. FormulaC38H54N8O10
Mol. Weight782.88

别名和识别编码

Chemical NameDeltorphin II
Synonym Tyr-D-Ala-Phe-Glu-Val-Val-Gly amide
MDL NumberMFCD00080072
PubChem Substance ID24899907
CAS Number122752-16-3
Chemical Name Translation德尔托啡肽II
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分类

  • {SNA} Neuropeptides, Opioid Peptides, Other Opioid Peptides, Peptides and Proteins, Peptides for Cell Biology, 细胞信号转导和神经科学, 细胞生物学
  • {SNA} Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, D-DIF, Neuropeptides, Opioid Peptides, Other Opioid Peptides, Peptides and Proteins, Peptides for Cell Biology
  • Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, D-DIF, Neuropeptides, Opioid Peptides, Other Opioid Peptides, Peptides and Proteins, Peptides for Cell Biology

相关文献及参考

  • Melchiorri, P., et al., Long-term sensitization to the activation of cerebral delta-opioid receptors by the deltorphin Tyr-D-Ala-Phe-Glu-Val-Val-Gly-NH2 in rats exposed to morphine. Proc. Natl. Acad. Sci. U. S. A. 89 , 3696-3700, (1992) 摘要
  • Thomas, S.A., Structure-activity relationships of a series of [D-Ala 2 ]-deltorphin I and II analogues; in vitro blood-brain barrier permeability and stability. J. Pharmacol. Exp. Ther. 281 , 817-825, (1997)
  • Tsuji, M., et al., Region-dependent G-protein activation by mu-, delta 1- and delta 2-opioid receptor agonists in the brain: comparison between the midbrain and forebrain. Life Sci. 65 , PL233-PL239, (1999)
  • [1]. Thomas SA, et al. Structure-activity relationships of a series of [D-Ala2]deltorphin I and II analogues; in vitro blood-brain barrier permeability and stability. J Pharmacol Exp Ther. 1997 May;281(2):817-25.

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

系列性分类


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