Arsenic(V) oxide 五氧化二砷(砒霜)

CAS 1303-28-2 MFCD00003434

化学结构图

1303-28-2
SMILES: O=[As](=O)O[As](=O)=O

化学属性

Mol. FormulaAs2O5
Mol. Weight229.84
Melting Point315° dec.
Density4.32
TSCAYes
SolubilityFreely soluble in water and alcohol

别名和识别编码

Chemical NameArsenic pentoxide
MDL NumberMFCD00003434
EC Number215-116-9
CAS Number1303-28-2
Synonym arsenicacid,anhydride arsenicpentoxide100/105000 ARSENIC (V) STANDARD Arsenic anhydride anhydridearsenique(french) ARSENIC OXIDE 氧化砷, 99.9% (METALS BASIS) Arsenic pentoxide rcrawastenumberp011 Arsenicpentaoxide arsenicoxide(as2o5) 五氧化二呻 ARSENIC PENTOXIDE Anhydride arsenique Arsenicacidanhydride Arsenic acid anhydride arsenicpentoxide100/ ARSENIC AA STANDARD 砷酸酐 Arsenic(V) oxide,( 99.9+%-As) anhydridearsenique 五氧化二砷 caswellno057 ARSENIC (V) OXIDE 五氧化砷 五氧化二砷(砒霜) ARSENIC AA STANDARD CONCENTRATE diarsenicpentoxide epapesticidechemicalcode006802 呻酸酐 无水砷酸 砷酐 RCRA waste number P011 Arsenic(V) oxide Diarsenic pentoxide
Merck Number14,798
PubChem Substance ID14771
Chemical Name Translation五氧化二砷(砒霜)
Wiswesser Line NotationAS2 O5
InChIInChI=1S/As2O5/c3-1(4)7-2(5)6
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分类

  • {SNA} Arsenic, Catalysis and Inorganic Chemistry, Chemical Synthesis

安全信息

RTECSCG2275000
Safety Statements
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S53 Avoid exposure - obtain special instructions before use 避免接触,使用前获得特别指示说明;
UN Number UN1559 1559
Risk Statements
  • R45 May cause cancer 可能致癌
  • R23/25 Toxic by inhalation and if swallowed 吸入及吞食都有毒
  • R50/53
Storage condition Poison room Hygroscopic
Packing GroupII
WGK Germany3
GHS Symbol
Precautionary statements
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P301+P310
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P311 Call a POISON CENTER or doctor/physician. 呼叫解毒中心或医生/医师。
Signal word Danger
Hazard statements
  • H350 May cause cancer 可能致癌
  • H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
  • H331 Toxic if inhaled 吸入中毒
  • H301 Toxic if swallowed 吞食有毒
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Hazard Codes T,N
Hazard Class6.1
Restrict 剧毒化学品
Warnings 危化品目录(2015) 危险化学品
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 12400 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 21,489,1911

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 8 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   28ZEAL "Pesticide Index," Frear, E.H., ed., State College, PA, College
   Science Pub., 1969  Volume(issue)/page/year: 5,14,1976

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 6 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: PB214-270

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 55 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   IRGGAJ Internationales Archiv fuer Gewerbepathologie und Gewerbehygiene.
   (Heidelberg, Fed. Rep. Ger.)  V.19-25, 1962-69.  For publisher information,
   see IAEHDW.  Volume(issue)/page/year: 20,21,1963

TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Human Fibroblast
DOSE/DURATION           : 100 umol/L
REFERENCE :
   IVTOE4 In Vitro Toxicology: A Journal of Molecular and Cellular Toxicology.
   (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128)   V.1-
   1986/87-  Volume(issue)/page/year: 1,103,1987

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Human Leukocyte
DOSE/DURATION           : 1200 nmol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 88,73,1981

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Rodent - hamster Fibroblast
DOSE/DURATION           : 3200 ug/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 104,141,1982

TYPE OF TEST            : DNA repair
TEST SYSTEM             : Bacteria - Bacillus subtilis
DOSE/DURATION           : 50 mmol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 77,109,1980

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 4597 ug/kg
SEX/DURATION            : male 30 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Paternal Effects - testes, epididymis, sperm duct
REFERENCE :
   JRPFA4 Journal of Reproduction and Fertility.  (Biochemical Soc. Book Depot,
   POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK)  V.1-    1960-
   Volume(issue)/page/year: 7,21,1964

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intratesticular
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 4597 ug/kg
SEX/DURATION            : male 1 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Paternal Effects - spermatogenesis (incl. genetic material,
   sperm morphology, motility, and count)
   Reproductive - Paternal Effects - testes, epididymis, sperm duct
REFERENCE :
   JRPFA4 Journal of Reproduction and Fertility.  (Biochemical Soc. Book Depot,
   POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK)  V.1-    1960-
   Volume(issue)/page/year: 7,21,1964

其他信息

  • 水中溶解度(g/100ml):每100毫升水中的溶解克数: 65.8g/20℃
  • 毒性分级:剧毒
  • 用途一:用于砷酸盐的制备,染料和印刷工业等,并可用作杀虫剂
  • 类别:农药
  • 爆炸物危险特性:与化合物RBC2起激烈反应
  • 上游原料:三氧化二砷
  • MOL 文件:1303-28-2.mol
  • 外观性质:白色无定形固体, 易潮解。
  • Alfa Aesar:氧化砷,99.9%(metalsbasis) Arsenic(V) oxide, 99.9% (metals basis)(1303-28-2)
  • 五氧化二砷(砒霜)价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 80012327 五氧化二砷(剧毒) 250g 520元 2010/06/21 366310050 五氧化二砷(砒霜) Arsenic(V) oxide 99.9+% 5 GR 871元 2010/06/21 366310250 五氧化二砷(砒霜) Arsenic(V) oxide 99.9+% 25 GR 2470元
  • MSDS 信息:五氧化二砷(1303-28-2).msds
  • 下游产品:8-硝基喹啉
  • 敏感性:Hygroscopic
  • 储运特性:库房通风低温干燥; 与碱、酸类、食品添加剂分开存放
  • 可燃性危险特性:不可燃物质; 遇热放出有毒砷化物蒸气
  • Acros Organics:Arsenic(V)oxide,99.9+%(1303-28-2)
  • 急性毒性:口服- 大鼠 LD50: 8 毫克/ 公斤; 口服- 小鼠 LD50: 55 毫克/ 公斤
  • Sigma Aldrich:1303-28-2(sigmaaldrich)
  • 职业标准:TLA-TWA 0.01 毫克(砷)/ 立方米

系列性分类