7-(Benzyloxy)Quinoline 7-苄氧基喹啉

CAS 131802-60-3 MFCD00870296

化学结构图

131802-60-3
SMILES: C(OC1=CC2N=CC=CC=2C=C1)C1C=CC=CC=1

化学属性

Mol. FormulaC16H13NO
Mol. Weight235.28

别名和识别编码

Chemical Name7-(Benzyloxy)Quinoline
MDL NumberMFCD00870296
CAS Number131802-60-3
Synonym 7-Benzyloxyquinoline
Chemical Name Translation7-苄氧基喹啉
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分类

  • {SNA} Application Index, B, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling Enzymes, Cell
  • {SNA} Application Index, Cell Signaling Enzymes, Cytochrome P450, Cytochrome P450 3A4, Detection and Quantitation, Drug and Xenobiotic Metabolism, Enzyme Substrates, Multi-Drug Resistance and Drug Metabolism, Reagents, Substrates by Enzyme, Xenobiotics And Drug Metabolism Substrates, Xenobiotics and Drug Metabolism, 生化试剂, 细胞信号转导和神经科学, 细胞生物学, 酶、抑制剂和底物
  • Application Index, B, Bioactive Small Molecules,

相关文献及参考

  • Stresser, D. M., Substrate-dependent modulation of CYP3A4 catalytic activity: analysis of 27 test compounds with four fluorometric substrates. Drug Metab. Dispos. 28 , 1440, (2000)
  • Lu, P., et al., Testosterone, 7-benzyloxyquinoline, and 7-benzyloxy-4-trifluoromethyl-coumarin bind to different domains within the active site of cytochrome P450 3A4. Drug Metab. Dispos. 29(11) , 1473-1479, (2001) 摘要

安全信息

GHS Symbol
WGK Germany3
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
Signal word Warning
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Hazard Codes Xi
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36 Wear suitable protective clothing 穿戴适当的防护服；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

系列性分类

  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Application Index - Enzymes, Inhibitors, and Substrates
  5. Cell Signaling Enzymes - Application Index
  6. Xenobiotics and Drug Metabolism - Cell Signaling Enzymes
  7. Substrates - Xenobiotics and Drug Metabolism
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Enzyme Substrates - Enzymes, Inhibitors, and Substrates
  5. Substrates by Enzyme - Enzyme Substrates
  6. Cytochrome P450 - Substrates by Enzyme

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