(+)-N-Allylnormetazocine hydrochloride
CAS 133005-41-1 MFCD00078552
化学结构图
SMILES: Cl.C[C@@H]1[C@@H]2CC3=CC=C(O)C=C3[C@@]1(C)CCN2CC=C
化学属性
| Mol. Formula | C17H23NO · HCl |
|---|---|
| Mol. Weight | 293.83 |
别名和识别编码
| Chemical Name | (+)-N-Allylnormetazocine hydrochloride |
|---|---|
| CAS Number | 133005-41-1 |
| Synonym | (+)-N-Allyl-N-normetazocine hydrochloride (+)-N-Allylnormetazocine hydrochloride (+)-NANM hydrochloride (+)-NANM hydrochloride SKF-10047 SKF10047 [2S-(2α, 6α,11R*)]-1,2,3,4,5,6-Hexahydro-6,11-dimethyl-3-(2-propenyl)-2,6-methano-3-benzazocin-8-ol hydrochloride (2S,6S,11S)-1,2,3,4,5,6-Hexahydro-6,11-dimethyl-3-(2-propen-1-yl)-2,6-methano-3-benzazocin-8-ol Hydrochloride D-NANM SKF-10047 SKF10047 [2S-(2α, 6α,11R*)]-1,2,3,4,5,6-Hexahydro-6,11-dimethyl-3-(2-propenyl)-2,6-methano-3-benzazocin-8-ol hydrochloride [2S-(2α, 6α,11R*)]-1,2,3,4,5,6-Hexahydro-6,11-dimethyl-3-(2-propenyl)-2,6-methano-3-benzazocin-8-ol hydrochloride |
| MDL Number | MFCD00078552 |
| PubChem Substance ID | 24278250 |
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分类
- A-AM, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Excitatory Amino Acids - Opiod Agonists, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, Membrane Protein Biology Tools, Neurobiology, Neuroscience, Opioid Agonists,
产品应用
- Normetazocine analogue as opioid antagonist.
相关文献及参考
- Martin, W., et al.: J. Pharmacol. Exp. Ther., 197, 517 (1976),
- Itzhak, Y., Pharmacological specificity of some psychotomimetic and antipsychotic agents for the σ and PCP binding sites. Life Sci. 42 , 745, (1988) 摘要
- Shimazu, S., et al., Sigma receptor ligands attenuate N-methyl-D-aspartate cytotoxicity in dopaminergic neurons of mesencephalic slice cultures. Eur. J. Pharmacol. 388 , 139-146, (2000) 摘要
- Wilke, R.A., et al., Sigma receptor photolabeling and sigma receptor-mediated modulation of potassium channels in tumor cells. J. Biol. Chem. 274 , 18387-18392, (1999) 摘要
- Bucolo, C., et al., σ1 recognition sites in rabbit iris-ciliary body: topical σ1-site agonists lower intraocular pressure. J. Pharmacol. Exp. Ther. 289 , 1362, (1999) 摘要
- Giulivi, C., et al., Basal Bioenergetic Abnormalities In Skeletal Muscle From Ryanodine Receptor Malignant Hyperthermia-susceptible R163C Knock-in Mice. J. Thorac. Cardiovasc. Surg. 286 , 99-113, (2011) 摘要
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