Tranylcypromine 反式-2-苯基环丙胺半硫酸盐

CAS 13492-01-8 MFCD00079222

化学结构图

13492-01-8
SMILES: N[C@@H]1C[C@H]1c1ccccc1.N[C@@H]1C[C@H]1c1ccccc1.O=S(=O)(O)O

化学属性

Mol. FormulaC9H11N · 1/2H2SO4
Mol. Weight182.23

别名和识别编码

Chemical NameTranylcypromine
Synonym Tranylcypromine 反式-2-苯基环丙胺 半硫酸盐 Phenylcyclopromine sulfate trans,D,L-2-Phenylcyclopropylamine sulfate Tranylcypromine sulfate (+-)-trans-2-Phenylcyclopropylamine sulfate (2:1) Parnate Cyclopropanamine, 2-phenyl-, trans-(+-)-, sulfate (2:1) 1-Amino-2-phenylcyclopropane sulfate Tranylcypromine sulphate 反苯环丙胺
MDL NumberMFCD00079222
CAS Number13492-01-8
EC Number236-807-1
Wiswesser Line NotationL3TJ AZ BR 2 &..H2.S-O4
Chemical Name Translation反式-2-苯基环丙胺半硫酸盐
PubChem Substance ID329820106
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分类

  • {SNA} Application Index, Bioactiv
  • {SNA} Application Index, Bioactive Small Molecule Alphabetical Index, Cell Signaling Enzymes, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme,
  • {SA} Application Index, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling Enzymes, Cell Signaling and Neuroscience,

相关文献及参考

  • Merck 14 ,9573

安全信息

RTECSGZ2625000
GHS Symbol
WGK Germany3
Precautionary statements
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P301+P310
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P311 Call a POISON CENTER or doctor/physician. 呼叫解毒中心或医生/医师。
Hazard statements
  • H331 Toxic if inhaled 吸入中毒
  • H311 Toxic in contact with skin 皮肤接触中毒
  • H300 Fatal if swallowed 吞食致命
Hazard Codes T
Personal Protective Equipment Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Signal word Danger
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 45 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ABMGAJ Acta Biologica et Medica Germanica.  (Berlin, Ger. Dem. Rep.) V.1-41,
   1958-82.  For publisher information, see BBIADT. Volume(issue)/page/year:
   18,617,1967

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 41 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJPHAZ European Journal of Pharmacology.  (Elsevier Science Pub. B.V., POB
   211, 1000 AE Amsterdam, Netherlands)  V.1-    1967- Volume(issue)/page/year:
   6,115,1969

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 34 mg/kg/60D-I
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - paresthesis
   Musculoskeletal - joints
REFERENCE :
   AJPSAO American Journal of Psychiatry.  (American Psychiatric Assoc.,
   Circulation Dept., 1400 K St., NW, Washington, DC 20005)  V.78-    1921-
   Volume(issue)/page/year: 140,1229,1983

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF E

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - woman
DOSE/DURATION           : 1200 ug/kg/3D-I
TOXIC EFFECTS :
   Vascular - BP lowering not characterized in autonomic section
REFERENCE :
   AJPSAO American Journal of Psychiatry.  (American Psychiatric Assoc.,
   Circulation Dept., 1400 K St., NW, Washington, DC 20005)  V.78-    1921-
   Volume(issue)/page/year: 144,119,1987

Safety Statements
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
Risk Statements
  • R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入,皮肤接触及吞食都有毒

系列性分类


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