Glycine, N-methyl-N-(1-oxododecyl)-, sodium salt (1:1) N-月桂酰肌氨酸钠

CAS 137-16-6 MFCD00042728

化学结构图

137-16-6
SMILES: CCCCCCCCCCCC(=O)N(C)CC(=O)[O-].[Na+]

化学属性

Mol. FormulaC15H28NNaO3
Mol. Weight293.38
Density1.033 g/mL at 20 °C
SolubilitySoluble in water (1 M) at 20 °C.
Stability对湿度敏感
Melting Point46 °C

别名和识别编码

Chemical NameGlycine, N-methyl-N-(1-oxododecyl)-, sodium salt (1:1)
Synonym Lauroylsarcosine (sodium) {LY} Lauroylsarcosine (sodium) {} {LY} Lauroylsarcosine (sodium) {} {} {LY} Lauroylsarcosine (sodium) {} {} {} {LY} Lauroylsarcosine (sodium) {} {} {} {} {LY} Lauroylsarcosine (sodium) {} {} {} {} {} {LY} Lauroylsarcosine (sodium) {} {} {} {} {} {} {LY} Lauroylsarcosine (sodium) {} {} {} {} {} {} {} {LY} Lauroylsarcosine (sodium) {} {} {} {} {} {} {} {} {LY} Lauroylsarcosine (sodium) {} {} {} {} {} {} {} {} {} {LY} Lauroylsarcosine (sodium) {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Lauroylsarcosine (sodium) {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Lauroylsarcosine (sodium) {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Lauroylsarcosine (sodium) {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Lauroylsarcosine (sodium) {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Lauroylsarcosine (sodium)
CAS Number137-16-6
PubChem Substance ID87571989
EC Number205-281-5
Beilstein Registry Number5322974
MDL NumberMFCD00042728
Reaxys-RN5322974
Merck Number4368
Chemical Name TranslationN-月桂酰肌氨酸钠
LabNetwork Molecule IDLN00227114
Canonical SMILESO=C(O[Na])CN(C)C(CCCCCCCCCCC)=O
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分类

  • {SNA} Anionic Detergents, Biochemicals and Reagents, Cell Lysis Reagents, Detergents, Detergents A to M, Detergents by Applications, Electrophoresis Chro
  • {SNA} Anionic Detergents, Biochemicals and Reagents, DNA和RNA纯化, Detergents, Detergents A to M, Detergents

产品应用

  • 阴离子表面活性剂。可用于RNA、DNA离析,作为细胞纯化中的溶解剂,从人血清中分离DNA时的添加剂,还可以通过添加该产品增加豆科植物根瘤菌的固氮能力,在免疫化学方面也有许多应用。

相关文献及参考

  • Merck: 14,4368 Beilstein: 4,IV,2387
  • Schmookler, R. J., Properties of the polyoma virus transcription complex obtained from mouse nuclei. Virology 57 , 122, (1974) 摘要
  • D.E. Mahoney, Lysis of Clostridium perfringens for the rapid extraction of plasmids. Appl. Environ. Microbiol. 51 , 521, (1986)
  • P. Gariglio, Useful for rupturing eukaryote cells in transcription studies. FEBS Lett. 44 , 330, (1974) 摘要
  • Wroblewski, W., Solubilization of Spiroplasma citri cell membrane proteins with the anionic detergent sodium lauroyl-sarcosinate (Sarkosyl). Biochimie 60 , 389, (1978) 摘要
  • Merck: 14,4368

安全信息

GHS Symbol
WGK Germany1
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H318 Causes serious eye damage 严重伤害眼睛
  • H330 Fatal if inhaled 吸入致命
Personal Protective Equipment Eyeshields, Gloves Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Precautionary statements
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P284 Wear respiratory protection.? 佩戴呼吸保护装置。
  • P302+P352+P332+P313+P362+P364
  • P304+P340+P310
  • P305+P351+P338
  • P305+P351+P338+P310
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P332+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Signal word Danger
RTECSMC0598960
UN Number 2811
Safety Statements
  • S22 Do not breathe dust 不要吸入粉尘;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S37/39 Wear suitable gloves and eye/face protection 穿戴适当的手套和眼睛/面保护;
  • S38 In case of insufficient ventilation wear suitable respiratory equipment 通风不良时,佩带适当的呼吸器;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
Hazard Codes 6.1 T
Risk Statements
  • R23 Toxic by inhalation 吸入有毒
  • R38 Irritating to skin 刺激皮肤
  • R41 Risk of serious damage to eyes 有严重损伤眼睛的危险
Packing GroupII
Hazard Class6.1
Storage condition 2-8°C, sealed storage, away from moisture {LY} 2-8°C, sealed storage, away from moisture Store at room temperature {} {LY} 2-8°C, sealed storage, away from moisture {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {}

其他信息

  • Lauroylsarcosine, sodium salt is an ionic detergent used to purify membrane proteins. Lauroylsarcosine, sodium salt also decreases transcription efficiency. Lauroylsarcosine, Sodium Salt is an inhibitor of HXK.

系列性分类


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