Amprolium Hydrochloride 氨丙啉盐酸盐

CAS 137-88-2 MFCD00078831

化学结构图

137-88-2
SMILES: CCCc1ncc(C[n+]2ccccc2C)c(N)n1.Cl.[Cl-]

化学属性

Mol. FormulaC14H19N4Cl
Mol. Weight315
Appearance 白色或类白色粉末,无臭或几乎无臭。1-(4-氨基-2-丙基-5-嘧啶甲基)-2-甲基吡啶氯化物盐酸盐(137-88-2)在水中易溶，在乙醇中微溶，在乙醚中极微溶解，在氯仿中不溶。
SolubilitySoluble in water (63 mg/ml at 25 °C), DMSO (2 mg/ml at 25 °C), ethanol (<1 mg/ml at 25 °C), methanol, and DMF
TSCANo
Melting Point239.0 to 243.0 deg-C

别名和识别编码

Chemical NameAmprolium Hydrochloride
Synonym 1-([4-AMINO-2-PROPYL-5-PYRIMIDINYL]METHYL)-2-METHYLPYRIDINIUM CHLORIDE 1-([4-Amino-2-propyl-5-pyrimidinyl]methyl)-2-methylpyridinium chloride 1-([4-氨基-2-丙基-5-嘧啶基]甲基)-2-甲基吡啶氯化物 氨丙啉 盐酸盐 1-[(4-Amino-2-propyl-5-pyrimidinyl)methyl]-2-methylpyridinium chloride hydrochloride 5-[(6-METHYLPYRIDIN-1-YL)METHYL]-2-PROPYL-PYRIMIDIN-4-AMINE CHLORIDE HYDROCHLORIDE AMPROLIUM HYDROCHLORIDE VETRANAL, 250 Amprol Mepyrium Pyridinium, 1-((4-amino-2-propyl-5-pyrimidinyl)methyl)-2-methyl-, Pyridinium, 1-(4-amino-2-propyl-5-pyrimidinyl)methyl-2-methyl-, chloride, monohydrochloride amprol25 amprol25percent pyridinium,1-((4-amino-2-propyl-5-pyrimidinyl)methyl)-2-methyl-,chloride,m 安保宁 安普罗林 氨丙啉 氨丙啉 盐酸盐 氨丙林 盐酸氨丙啉 盐酸氨丙林
Beilstein Registry Number4118699
PubChem Substance ID253659663
CAS Number137-88-2
EC Number205-307-5
MDL NumberMFCD00078831
Chemical Name Translation氨丙啉盐酸盐
Reaxys-RN4118699
LabNetwork Molecule IDLN01740167
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分类

  • {SNA} Analytical Standards, Analytical/Chromatography, Chromatography, Pharmaceutical Standards, Pharmacopeia Standards, USP Standards, USP Standards A - B
  • {Chem
  • {SNA} Biochemicals and Reagents, Cationic Detergents, Detergents, Detergents A to M
  • {SNA} Cationic Detergents, Detergents A to M, 去垢剂, 生化试剂
  • {SNA} Analytical Standards, Chromatography, Pharmaceutical Standards, Pharmacopeia Standards, USP Standards, USP Standards A - B, 分析/色谱
  • {SNA} A, AM to AQ, Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography,
  • {SNA} Additional Standards,

产品应用

  • Thiamine analog coccidiostat.

安全信息

RTECSTJ7565000
WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Safety Statements
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
Storage condition 储存温度-20°C 储存温度 2-8°C
Signal word Warning
GHS Symbol
Precautionary statements
  • P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛，皮肤或衣服。
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 10 mg/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 77,21,1980

其他信息

  • Amprolium HCl是Vitamin B1的拮抗剂，通过抑制Vitamin B1的吸收而阻止碳水化合物的合成。
  • Sigma Aldrich:137-88-2(sigmaaldrich)
  • 用途一:用作抗球虫药，对鸡艾美耳球虫、柔嫩与堆形艾美耳球虫、羔羊及犊牛球虫都有效
  • MOL 文件:137-88-2.mol
  • 用途三:抗球虫病。
  • 参考质量标准:农业部标准 含量(干基)/% 97.5~101.0 甲基吡啶/% ≤1.0 干燥失重/% ≤2.0 灼烧残渣/% ≤0.5
  • 方法一:以生产维生素B1的中间体为原料，经环合、水解开环，再经重氮化使氨基转化为羟基，最后经缩合而得。
  • 用途二:抗球虫药物，效果好，残留量少，可以预防、治疗鸡球虫病，并能促进生长。用于鸡饲料，用量为62.5-125g/t。通常还可以与乙氧酰胺苯甲酯按125：8混合成二合剂，用量为(62.5+4—125+8)g/t，停药期7天，产蛋期禁用。与与乙氧酰胺苯甲酯和磺胺喹喔啉按100：5：60混合成三合剂，最高用量为（100+5+60）g/t，产蛋期禁用，停药期7天。
  • 氨丙啉

系列性分类

  1. Application Areas 应用领域分类
  2. Detergents 去污剂洗净剂
  3. Detergents A to M - Detergents
  1. Application Areas 应用领域分类
  2. Detergents 去污剂洗净剂
  3. Anionic Detergents - Detergents
  1. Application Areas 应用领域分类
  2. Detergents 去污剂洗净剂
  3. Cationic Detergents - Detergents
  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Chromatography - Analytical Standards
  4. Clinical Standards - Chromatography
  5. Antibiotics - Clinical Standards
  6. Principle - Antibiotics
  7. Bactericidal - Principle

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