16Α-Hydroxyprednisolone 16α-羟基泼尼松龙
CAS 13951-70-7 MFCD00872019
化学结构图
SMILES: C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@@]43C)[C@@H]1C[C@@H](O)[C@]2(O)C(=O)CO
化学属性
| Mol. Formula | C21H28O6 |
|---|---|
| Mol. Weight | 376.45 |
别名和识别编码
| Chemical Name | 16Α-Hydroxyprednisolone |
|---|---|
| CAS Number | 13951-70-7 |
| Synonym | (11?,16?)-11,16,17,21-Tetrahydroxypregna-1,4-diene-3,20-dione 16?-Hydroxyprednisolone 11a,16b,17,21-Tetrahydroxy-pregna-1,4-diene-3,20-dione |
| EC Number | 237-731-1 |
| Chemical Name Translation | 16α-羟基泼尼松龙 |
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分类
- Metabolites & Impurities
- Pharmaceuticals
- Intermediates & Fine Chemicals
- Steroids
产品应用
- A metabolite of Budesonide (B689490), an antiinflammatory agent.
相关文献及参考
- [2]. G Jönsson, et al. Budesonide is metabolized by cytochrome P450 3A (CYP3A) enzymes in human liver. Drug Metab Dispos. 1995 Jan;23(1):137-42.
- Buchwald, P., et al.: Steroids, 73, 193 (2008),
- Cserhati, T., et al.: J. Pharm. Biomed. Anal., 22, 25 (2000),
- Dilger, K., et al.: J. Clin. Pharmacol., 47, 1532 (2007),
- [1]. Xavier Matabosch, et al. Identification of budesonide metabolites in human urine after oral administration. Anal Bioanal Chem. 2012 Aug;404(2):325-40.
- [1]. Xavier Matabosch, et al. Identification of budesonide metabolites in human urine after oral administration. Anal Bioanal Chem. 2012 Aug;404(2):325-40.
- [2]. G Jönsson, et al. Budesonide is metabolized by cytochrome P450 3A (CYP3A) enzymes in human liver. Drug Metab Dispos. 1995 Jan;23(1):137-42.
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