Naratriptan hydrochloride 那拉曲坦盐酸盐
CAS 143388-64-1 MFCD08141821
化学结构图
SMILES: CNS(=O)(=O)CCc1ccc2[nH]cc(C3CCN(C)CC3)c2c1.Cl
化学属性
| Mol. Formula | C17H26ClN3O2S |
|---|---|
| Mol. Weight | 372 |
别名和识别编码
| Chemical Name | Naratriptan hydrochloride |
|---|---|
| CAS Number | 143388-64-1 |
| Synonym | 1H-indole-5-ethanesulfonamide, N-methyl-3-(1-methyl-4-piperidinyl)-, monohydrochloride Amerge Amerge GR-85548A N-Methyl-3-(1-methyl-4-piperidinyl)-1H-indole-5-ethanesulfonamide hydrochloride Colatan GR 85548A GR-85548A N-Methyl-2-[3-(1-methyl-4-piperidyl)-1H-indol-5-yl]ethanesulfonamide Hydrochloride N-Methyl-3-(1-methyl-4-piperidinyl)-1H-indole-5-ethanesulfonamide hydrochloride N-methyl-3-(1-methyl-4-piperidinyl)-1H-indole-5-ethanesulfonamide N-methyl-3-(1-methyl-4-piperidyl)indole-5-ethanesulfonamide monohydrochloride Naramig Naratriptan hydrochloride naratriptan naratriptan hydrochloride |
| MDL Number | MFCD08141821 |
| PubChem Substance ID | 60875 |
| Chemical Name Translation | 那拉曲坦盐酸盐 |
| InChI | InChI=1S/C17H25N3O2S.ClH/c1-18-23(21,22)10-7-13-3-4-17-15(11-13)16(12-19-17)14-5-8-20(2)9-6-14;/h3-4,11-12,14,18-19H,5-10H2,1-2H3;1H |
| LabNetwork Molecule ID | LN01300572 |
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分类
- Pharmaceuticals
- {SNA} Agonists, Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, GlaxoSmithKline, Membrane Protein Biology Tools, N, Neuroscience,
产品应用
- It is a triptan drug and is used for the treatment of migraine headaches.
相关文献及参考
- Dulery, B.D., et al.: J. Pharm. Biomed. Anal., 15, 1009 (1997),
- Havanka, H., et al.: Clin. Ther., 22, 970 (2000),
- [1]. Connor HE, et al. Naratriptan: biological profile in animal models relevant to migraine. Cephalalgia. 1997 May;17(3):145-52.
安全信息
GHS Symbol
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P305+P351+P338
- P337+P313
- H319 Causes serious eye irritation 严重刺激眼睛
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- R36 Irritating to eyes 刺激眼睛
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