AC-YVAD-AMC

CAS 149231-65-2 MFCD00171369

化学结构图

149231-65-2
SMILES: CC(C)[C@H](NC(=O)[C@H](CC1=CC=C(O)C=C1)NC(C)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)NC1C=CC2=C(C=1)OC(=O)C=C2C

化学属性

Mol. FormulaC33H39N5O10
Mol. Weight665.69

别名和识别编码

Chemical NameN-Acetyl-Tyr-Val-Ala-Asp-7-amido-4-methylcoumarin
Synonym Ac-YVAD-AMC
MDL NumberMFCD00171369
PubChem Substance ID24890658
CAS Number149231-65-2
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分类

  • {SA} A-AM, Apoptosis Enzymes, Apoptosis and Cell Cycle, Application Index, Bioactive Small Molecules,
  • {SNA} Apoptosis Enzymes, Apoptosis and Cell Cycle, Application Index, Caspase 1, Caspase 1 Substrates, Caspase 4, Caspase 4 Substrates, Caspase Inhibitors and Substrates, Caspase Substrates, Caspases, Caspases Substrates, Cell Signaling Enzymes, Enzyme Substrates, Peptides and Proteins, Peptides for Cell Biology, Substrates, Substrates by Enzyme, 生化试剂, 细胞信号转导和神经科学, 细胞生物学, 酶、抑

相关文献及参考

  • Schafer, R., Multiple intracellular pathways interfere with the activation of a CPP32-like protease induced by serum deprivation of AKR‑2B cells. Exp. Cell Res. 240 , 28, (1998) 摘要
  • Inayat-Hussain S.H., Processing/activation of CPP32-like proteases is involved in transforming growth factor β 1 induced apoptosis in rat hepatocytes. Hepatology 25 , 1516, (1997) 摘要
  • Takahashi, T., et al., Partial purification and characterization of two distinct types of caspases from human epidermis. J. Invest. Dermatol. 111 , 367-372, (1998) 摘要
  • Fassy, F., Enzymatic activity of two caspases related to interleukin-1β converting enzyme. Eur. J. Biochem. 253 , 76, (1998) 摘要
  • Thornberry, N.A., A novel heterodimeric cysteine protease is required for interleukin-1β processing in monocytes. Nature 356 , 768, (1992) 摘要

安全信息

WGK Germany3

系列性分类

  1. Caspase Inhibitors and Substrates - Peptides for Cell Biology
  2. Caspase Substrates - Caspase Inhibitors and Substrates
  3. Caspase 1 - Caspase Substrates
  1. Caspase Inhibitors and Substrates - Peptides for Cell Biology
  2. Caspase Substrates - Caspase Inhibitors and Substrates
  3. Caspase 4 - Caspase Substrates
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Apoptosis and Cell Cycle - Cell Signaling and Neuroscience
  5. Caspases - Apoptosis and Cell Cycle
  6. Substrates - Caspases
  7. Caspase 1 - Substrates
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Apoptosis and Cell Cycle - Cell Signaling and Neuroscience
  5. Caspases - Apoptosis and Cell Cycle
  6. Substrates - Caspases
  7. Caspase 3 - Substrates
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Apoptosis and Cell Cycle - Cell Signaling and Neuroscience
  5. Caspases - Apoptosis and Cell Cycle
  6. Substrates - Caspases
  7. Caspase 4 - Substrates
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Enzyme Substrates - Enzymes, Inhibitors, and Substrates
  5. Substrates by Enzyme - Enzyme Substrates
  6. Caspase 1 - Substrates by Enzyme
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Enzyme Substrates - Enzymes, Inhibitors, and Substrates
  5. Substrates by Enzyme - Enzyme Substrates
  6. Caspase 4 - Substrates by Enzyme
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Apoptosis and Cell Cycle - Cell Signaling and Neuroscience
  5. Caspases - Apoptosis and Cell Cycle
  6. Inhibitors - Caspases
  7. Caspase 1 - Inhibitors

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