Pranlukast hemihydrate
CAS 150821-03-7 MFCD00940160
化学结构图
SMILES: O.O=C(NC1=CC=CC2=C1OC(=CC2=O)C1NN=NN=1)C1C=CC(=CC=1)OCCCCC1C=CC=CC=1
化学属性
| Mol. Formula | C54H48N10O9 |
|---|---|
| Mol. Weight | 981 |
别名和识别编码
| Chemical Name | Pranlukast hemihydrate |
|---|---|
| CAS Number | 150821-03-7 |
| Alfabeta Name | PRANLUKASTHEMIHYDRATE |
| MDL Number | MFCD00940160 |
| Synonym | 8-[4(4-phenylbutoxy)benzoyl]amino-2-(5-tetrazolyl)-4-oxo-4H-1-benzopyran |
| Chemical Name Translation |
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分类
- Arachidonic Acid Cascade, Cell Biology, Cell Signaling and Neuroscience, Leukotrienes, Lipids in Cell Signaling
相关文献及参考
- [2]. Fang SH, et al. Nuclear translocation of cysteinyl leukotriene receptor 1 is involved in oxygen-glucose deprivation-induced damage to endothelial cells. Acta Pharmacol Sin. 2012 Dec;33(12):1511-7.
- [3]. Ogata M, et al. Protective effects of a leukotriene inhibitor and a leukotriene antagonist on endotoxin-induced mortality in carrageenan-pretreated mice. Infect Immun. 1992 Jun;60(6):2432-7.
- Merck 14 ,7710
- [1]. Obata T, et al. In vitro antagonism of ONO-1078, a newly developed anti-asthma agent, against peptide leukotrienes in isolated guinea pig tissues. Jpn J Pharmacol. 1992 Nov;60(3):227-37.
- [1]. Obata T, et al. In vitro antagonism of ONO-1078, a newly developed anti-asthma agent, against peptide leukotrienes in isolated guinea pig tissues. Jpn J Pharmacol. 1992 Nov;60(3):227-37.
- [2]. Fang SH, et al. Nuclear translocation of cysteinyl leukotriene receptor 1 is involved in oxygen-glucose deprivation-induced damage to endothelial c
安全信息
GHS Symbol
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P305+P351+P338
- H413 Maycauselonglastingharmfuleffectstoaquaticlife 可能对水生生物造成长期持续有害影响。
- H315 Causes skin irritation 会刺激皮肤
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- H302 Harmful if swallowed 吞食有害
- H319 Causes serious eye irritation 严重刺激眼睛
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