Ginkgolide B 银杏内酯 B

CAS 15291-77-7 MFCD05662347

化学结构图

15291-77-7
SMILES: CC(C)(C)[C@@H]1C[C@H]2OC(=O)[C@@]34O[C@@H]5OC(=O)[C@H](O)[C@]51[C@]32[C@@H](O)[C@@H]1OC(=O)[C@@H](C)[C@]41O

化学属性

Mol. FormulaC20H24O10
Mol. Weight424.40
TSCANo
Melting Point>300

别名和识别编码

Chemical NameGinkgolide B
CAS Number15291-77-7
Synonym 银杏内酯 B (1R,3S,3aS,4R,6aR,7aR,7bR,8S,10aS,11R,11aR)-3-(1,1-Dimethylethyl)hexahydro-4,7b,11-trihydroxy-8-methyl-9H-1,7a-(epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3',2':3,4]cyclopenta[1,2-d]furan-5,9,1 银杏内酯 B 来源于银杏 叶 BN-52021
MDL NumberMFCD05662347
PubChem Substance ID24895280
Beilstein Registry Number4727611
Merck Number14,4426
Chemical Name Translation银杏内酯 B
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分类

  • {SNA} Analytical Standards, Antioxidant and Free Radical Scavengers, Asymmetric Synthesis, Chemical Synthesis, Chemopreventive Agents, Chiral Building Blocks, Complex Molecules, Isoprenoids, Phytochemical Standards, Phytochemicals by Chemical Classification, Terpenes and Terpenoids (Isoprenoids), 分析/色谱, 癌症研究, 细胞生物学, 营养研究
  • {SNA} Analytical Standards,
  • {SNA} Alphabetical, Analytical Standards, Analytical/Chromatography, Chromatography, E - H, Ginkgo, Ginkgo biloba, Isoprenoids, Life Sciences Standards, Natural Compounds,
  • Pharmaceuticals
  • {SN

产品应用

  • Family of bioactive terpenes treating cardiovascular and cerebrovascular diseases. Specific platelet activating factor (PAF) antagonists.

相关文献及参考

  • [2]. Matyas Koltai, et al. Ginkgolide B protects isolated hearts against arrhythmias induced by ischemia but not reperfusion. European Journal of Pharmacology, 1989, 164 (2): 293-302
  • Braquet, P., et al.: Med. Res. Rev., 11, 295 (1991),
  • Korth, R., et al.: Eur. J. Pharmacol., 152, 101 (1988),
  • [1]. Jean R. Rapin, et al. In vitro and in vivo effects of an extract of Ginkgo biloba (EGb 761), ginkgolide B, and bilobalide on apoptosis in primary cultures of rat hippocampal neurons. Drug Development Research, 1998, 45 (1):1-43
  • [1]. Jean R. Rapin, et al. In vitro and in vivo effects of an extract of Ginkgo biloba (EGb 761), ginkgolide B, and bilobalide on apoptosis in primary cultures of rat hippocampal neurons. Drug Development Research, 1998, 45 (1):1-43
  • [2]. Matyas Koltai, et al. Ginkgolide B protects isolated hearts against arrhythmias induced by ischemia but not reperfusion. European Journal of Pharmacology, 1989, 164 (2): 293-302

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
GHS Symbol
Safety Statements
Precautionary statements

系列性分类

  1. Life Science 生命科学
  2. Cancer Research
  3. Chemopreventive Agents - Cancer Research
  4. Antioxidant and Free Radical Scavengers - Chemopreventive Agents
  1. Chemical Synthesis 化学合成
  2. Asymmetric Synthesis 不对称合成
  3. Chiral Building Blocks 手性分子砌块
  4. Complex Molecules - Chiral Building Blocks
  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Chromatography - Analytical Standards
  4. Life Sciences Standards - Chromatography
  5. Natural Compounds - Life Sciences Standards
  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Chromatography - Analytical Standards
  4. Life Sciences Standards - Chromatography
  5. Phytopharma Standards - Life Sciences Standards
  6. Alphabetical - Phytopharma Standards
  7. E - H - Alphabetical
  1. Medical Research Areas
  2. Metabolism
  3. Endogenous Metabolite  (内源性代谢物)

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