2-hydroxy-6-pentadecylbenzoic acid 2-羟基-6-十五烷基苯甲酸

CAS 16611-84-0 MFCD07368254

化学结构图

16611-84-0
SMILES: CCCCCCCCCCCCCCCC1C=CC=C(O)C=1C(O)=O

化学属性

Mol. FormulaC22H36O3
Mol. Weight348.52

别名和识别编码

Chemical Name2-hydroxy-6-pentadecylbenzoic acid
Synonym (15:0)-Anacardic acid 2-Hydroxy-6-pentadecylbenzoic acid 22:0-Anacardic acid 22:0-Anacardic acid 2-Hydroxy-6-pentadecylbenzoic acid 6-Pentadecylsalicylic acid 6-Pentadecylsalicylic acid
MDL NumberMFCD07368254
CAS Number16611-84-0
Chemical Name Translation2-羟基-6-十五烷基苯甲酸
PubChem Substance ID329770923
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分类

  • {SNA} AN-AZ, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules for Epigenetic Research, DNA-RNA Transcription Regulators, Gene Regulation and Expression, Histone Acetyltransferase Inhibitors, 分子生物学, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学, 表观遗传学
  • AN-AZ, Bioactive Small Molecules, Bioactive Small Molecules for Epigenetic Research, Cell Biology, Cell Signaling and Neuroscience, DNA-RNA Transcription Regulators, Epigenetics, Gene Regulation and Expression, Histone Acetyltransferase Inhibitors, Molecular Biology
  • {SNA} A - D, Alcohols and Phenols, Alphabetical,

相关文献及参考

  • Hemshekhar, M., et al., Emerging Roles of Anacardic Acid and Its Derivatives: A Pharmacological Overview Basic Clin Pharmacol Toxicol. , doi: 10.1111/j.1742-7843.2011.00833.x., (2011)
  • Ghizzoni, M., et al., 6-alkylsalicylates are selective Tip60 inhibitors and target the acetyl-CoA binding site Eur. J. Med. Chem. 47 , 337-44, (2012)
  • Devipriya, B. and Kumaradhas, P., Probing the effect of intermolecular interaction and understanding the electrostatic moments of anacardic acid in the active site of p300 enzyme via DFT and charge density analysis J. Mol. Graph. Model. 34 , 57-66, (2012)
  • Zheng, Y.G., et al., Chemical Regulation of Epigenetic Modifications: Opportunities for New Cancer Therapy. Med. Res. Rev. 28 , 645-687, (2008)
  • Kuhn, A.N., et al., Stalling of spliceosome assembly at distinct stages by small-molecule inhibitors of protein acetylation and deacetylation. RNA 15 , 153-175, (2009) 摘要

安全信息

GHS Symbol
Precautionary statements
  • P305+P351+P338
Signal word Warning
Hazard statements
  • H319 Causes serious eye irritation 严重刺激眼睛
WGK Germany3
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
Hazard Codes Xi
Risk Statements
  • R36 Irritating to eyes 刺激眼睛

系列性分类


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