(4S,7S,10S,13S)-7-(2-Carboxyethyl)-4-(Carboxymethyl)-10-Isopropyl-13-((4-Methyl-2-Oxo-2H-Chromen-7-Yl)Carbamoyl)-2,5,8,11-Tetraoxo-3,6,9,12-Tetraazapentadecan-15-Oic Acid (4S,7S,10S,13S)-7-(2-羧乙基)-4-(羧甲基)-10-异丙基-13-((4-甲基-2-氧代-2H-苯并吡喃-7-基)氨基甲酰基)-2,5,8,11-四氧代-3,6,9,12-四氮杂十五烷-15-酸

CAS 169332-61-0 MFCD00671411

化学结构图

169332-61-0
SMILES: CC(C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(C)=O)C(=O)N[C@@H](CC(O)=O)C(=O)NC1=CC=C2C(=C1)OC(=O)C=C2C

化学属性

Mol. FormulaC30H37N5O13
Mol. Weight675.64

别名和识别编码

Chemical Name(4S,7S,10S,13S)-7-(2-Carboxyethyl)-4-(Carboxymethyl)-10-Isopropyl-13-((4-Methyl-2-Oxo-2H-Chromen-7-Yl)Carbamoyl)-2,5,8,11-Tetraoxo-3,6,9,12-Tetraazapentadecan-15-Oic Acid
Synonym Ac-DEVD-AMC
MDL NumberMFCD00671411
PubChem Substance ID24890505
CAS Number169332-61-0
Chemical Name Translation(4S,7S,10S,13S)-7-(2-羧乙基)-4-(羧甲基)-10-异丙基-13-((4-甲基-2-氧代-2H-苯并吡喃-7-基)氨基甲酰基)-2,5,8,11-四氧代-3,6,9,12-四氮杂十五烷-15-酸
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分类

  • {SNA} A-AM, Apoptosis Enzymes, Apoptosis Reagents, Apoptosis and Cell Cycle, Application Index, Bioactive Small Molecule Alphabetical Index, Caspase 3, Caspase 3 Substrates, Caspase 7, Caspase 7 Substrates, Caspase Inhibitors and Substrates, Caspase Substrates, Caspases, Caspases Substrates, Cell Signaling Enzymes, Enzyme Substrates, Fluorimetric, Other Apoptosis Related Reagents, Peptides and Proteins, Peptides for Cell Biology, Substrates by Enzyme, 生化试剂, 生物活性小分子, 细胞信号转导和神经科学,

相关文献及参考

  • Nicholson, D.W., Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature 376 , 37, (1995) 摘要
  • Marks, N., Activation of caspase-3 and apoptosis in cerebellar granule cells. J. Neurosci. Res. 52 , 334, (1998)
  • He, J., et al., Protease activation and cleavage of poly(ADP-ribose) polymerase: an integral part of apoptosis in response to photodynamic treatment. Cancer Res. 58 , 940-946, (1998)
  • Armstrong, R.C., et al., Activation of the CED3/ICE-related protease CPP32 in cerebellar granule neurons undergoing apoptosis but not necrosis. J. Neurosci. 17 , 553-562, (1997) 摘要

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Apoptosis and Cell Cycle - Cell Signaling and Neuroscience
  5. Other Apoptosis Related Reagents - Apoptosis and Cell Cycle
  6. Apoptosis Reagents - Other Apoptosis Related Reagents
  1. Caspase Inhibitors and Substrates - Peptides for Cell Biology
  2. Caspase Substrates - Caspase Inhibitors and Substrates
  3. Caspase 7 - Caspase Substrates
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Apoptosis and Cell Cycle - Cell Signaling and Neuroscience
  5. Caspases - Apoptosis and Cell Cycle
  6. Substrates - Caspases
  7. Caspase 3 - Substrates
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Apoptosis and Cell Cycle - Cell Signaling and Neuroscience
  5. Caspases - Apoptosis and Cell Cycle
  6. Substrates - Caspases
  7. Caspase 7 - Substrates
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Enzyme Substrates - Enzymes, Inhibitors, and Substrates
  5. Substrates by Enzyme - Enzyme Substrates
  6. Caspase 3 - Substrates by Enzyme
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Enzyme Substrates - Enzymes, Inhibitors, and Substrates
  5. Substrates by Enzyme - Enzyme Substrates
  6. Caspase 7 - Substrates by Enzyme

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