U-104 4-(3-(4-氟苯基)脲基)苯磺酰胺

CAS 178606-66-1 MFCD00159265

化学结构图

178606-66-1
SMILES: NS(=O)(=O)c1ccc(NC(=O)Nc2ccc(F)cc2)cc1

化学属性

Mol. Weight309.32
Mol. FormulaC13H12FN3O3S

别名和识别编码

Synonym 4-[[[(4-Fluorophenyl)amino]carbonyl]amino]-benzenesulfonamide NSC 213841 U-104
Chemical NameU-104
MDL NumberMFCD00159265
PubChem Substance ID310360
Chemical Name Translation4-(3-(4-氟苯基)脲基)苯磺酰胺
LabNetwork Molecule IDLN00331168
InChIInChI=1S/C13H12FN3O3S/c14-9-1-3-10(4-2-9)16-13(18)17-11-5-7-12(8-6-11)21(15,19)20/h1-8H,(H2,15,19,20)(H2,16,17,18)
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分类

  • {SNA} A to C, Biochemicals and Reagents, Carbonic anhydrase, Cell Biology, Cell Signaling and Neuroscience, Cell Stress, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, Nitric Oxide and Cell Stress, Oxidative Stress Proteins and Reagents
  • {SNA} A to C, Bioactive Small Molecule Alphabetical Index, Carbonic anhydrase, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, U, 一氧化氮和细胞应激, 氧化应激蛋白和试剂, 生化试剂, 生物活性小分子, 细胞信号转导和神经科学, 细胞应激, 细胞生物学, 酶、抑制剂和底物

相关文献及参考

  • [2]. Lock FE, et al. Targeting carbonic anhydrase IX depletes breast cancer stem cells within the hypoxic niche. Oncogene. 2013 Oct 31;32(44):5210-9.
  • [3]. Huarui Zhang, et al. Advances in the discovery of exosome inhibitors in cancer. J Enzyme Inhib Med Chem. 2020 Dec;35(1):1322-1330.
  • [1]. Lou Y, et al. Targeting tumor hypoxia: suppression of breast tumor growth and metastasis by novel carbonic anhydrase IX inhibitors. Cancer Res. 2011 May 1;71(9):3364-76.
  • [1]. Lou Y, et al. Targeting tumor hypoxia: suppression of breast tumor growth and metastasis by novel carbonic anhydrase IX inhibitors. Cancer Res. 2011 May 1;71(9):3364-76.
  • [2]. Lock FE, et al. Targeting carbonic anhydrase IX depletes breast cancer stem cells within the hypoxic niche. Oncogene. 2013 Oct 31;32(44):5210-9.
  • [3]. Huarui Zhang, et al. Advances in the discovery of exosome inhibitors in cancer. J Enzyme Inhib Med Chem. 2020 Dec;35(1):1322-1330.

安全信息

Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
WGK Germany3
Hazard Codes Xi
Risk Statements
  • R36 Irritating to eyes 刺激眼睛
Hazard statements
  • H319 Causes serious eye irritation 严重刺激眼睛
Precautionary statements
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P305+P351+P338
  • P337+P313

系列性分类


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