Oseltamivir Acid 奥斯他伟酸

CAS 187227-45-8 MFCD00953940

化学结构图

187227-45-8
SMILES: CC(=O)N[C@@H]1[C@@H](N)CC(=C[C@H]1OC(CC)CC)C(O)=O |&1:4,5,10|

化学属性

Mol. FormulaC14H24N2O4
Mol. Weight284

别名和识别编码

Chemical NameOseltamivir Acid
CAS Number187227-45-8
Synonym (3R,4R,5S)-
Chemical Name Translation奥斯他伟酸
MDL Number
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分类

  • Amines
  • Metabolites & Impurities
  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

  • A metabolite of Oseltamivir.

相关文献及参考

  • [2]. Ghosh GC, et al. Oseltamivir carboxylate, the active metabolite of oseltamivir phosphate (Tamiflu), detected in sewage discharge and river water in Japan. Environ Health Perspect. 2010 Jan;118(1):103-7.
  • [3]. Ferraris O, et al. Sensitivity of influenza viruses to zanamivir and oseltamivir: a study performed on viruses circulating in France prior to the introduction of neuraminidase inhibitors in clinical practice. Antiviral Res. 2005 Oct;68(1):43-8.
  • [4]. Gubareva LV, et al. Comparison of the activities of zanamivir, oseltamivir, and RWJ-270201 against clinical isolates of influenza virus and neuraminidase inhibitor-resistant variants.Antimicrob Agents Chemother. 2001 Dec;45(12):3403-8.
  • [5]. Yen HL, et al. Virulence may determine the necessary duration and dosage of oseltamivir treatment for highly pathogenic A/Vietnam/1203/04 influenza virus in mice. J Infect Dis. 2005 Aug 15;192(4):665-72.
  • [6]. Hoffmann G, et al. Nonclinical pharmaco

系列性分类

  1. Medical Research Areas
  2. Metabolism
  3. Drug Metabolite  (药物代谢物)

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