Sulfamethazine Sodium Salt 磺胺二甲基嘧啶钠盐
CAS 1981-58-4 MFCD00068333
化学结构图
SMILES: Cc1cc(C)nc([N-]S(=O)(=O)c2ccc(N)cc2)n1.[Na+]
化学属性
| Mol. Formula | C12H13N4NaO2S |
|---|---|
| Mol. Weight | 300 |
| Density | 1.392 |
| Stability | 对光和热敏感 |
别名和识别编码
| Chemical Name | Sulfamethazine Sodium Salt |
|---|---|
| MDL Number | MFCD00068333 |
| CAS Number | 1981-58-4 |
| Synonym | Sulfamethazine sodium salt 4-Amino-N-(4,6-dimethyl-2-pyrimidinyl)benzenesulfonamide 2-(对氨基苯磺酰胺基)-4,6-二甲嘧啶钠 磺胺二甲基嘧啶 钠盐 Benzenesulfonamide, 4-amino-N-(4,6-dimethyl-2-pyrimidinyl)-, monosodium 磺胺二甲嘧啶钠 2-(对氨基苯磺酰胺基)-4,6-二甲嘧啶钠盐 磺胺二甲嘧啶钠盐 2-(对氨基苯磺酰胺基)-4,6-二甲嘧啶钠;N-(4,6-二甲基-2-嘧啶基)-4-氨基苯磺酰胺钠盐 4-Amino-N-(4,6-dimethyl-2-pyrimidinyl)benzenesulfonamide sodium salt |
| PubChem Substance ID | 87560231 |
| EC Number | 217-840-0 |
| Chemical Name Translation | 磺胺二甲基嘧啶钠盐 |
| Reaxys-RN | 6761844 |
| Merck Number | 8915 |
| Wiswesser Line Notation | T6NJ CNJ BMR D2SZW &-NA- |
| InChI | InChI=1S/C12H13N4O2S.Na/c1-8-7-9(2)15-12(14-8)16-19(17,18)11-5-3-10(13)4-6-11;/h3-7H,13H2,1-2H3;/q-1;+1 |
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分类
- {SNA} Antibacter
- {SNA} Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics N-S, Chemical Structure Class, Inhibits an Enzyme, Interferes with DNA Synthesis, L - Z, Mechanism of Action, Spectrum of Activity, Sulfonamides
- {SNA} Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics N-S, Biochemicals and Reagents, Chemical Structure Class, Inhibits an Enzyme, Interferes with DNA Synthesis, L - Z, Mechanism of Action, Spectrum of Activity, Sulfonamides
- {SNA} Antibacterial, Antibiotics A to Z, Antibiotics N-S,
- {SNA} Antibacterial,
产品应用
- 磺胺类药，用于脑膜炎、肺炎球菌、溶血性链球菌及某些革兰氏阴性杆菌所引起的感染。
安全信息
GHS Symbol
- H302 Harmful if swallowed 吞食有害
- S36 Wear suitable protective clothing 穿戴适当的防护服；
- R22 Harmful if swallowed 吞咽有害
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
- P301+P312+P330
- P501 Dispose of contents/container to..… 处理内容物/容器.....
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1165 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : MIMEAO Minerva Medica. (Edizioni Minerva Medica, Casella Postale 491, I-10126 Turin, Italy) V.1- 1909- Volume(issue)/page/year: 52,1789,1961
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 605 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : MIMEAO Minerva Medica. (Edizioni Minerva Medica, Casella Postale 491, I-10126 Turin, Italy) V.1- 1909- Volume(issue)/page/year: 52,1789,1961
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 699 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : MIMEAO Minerva Medica. (Edizioni Minerva Medica, Casella Postale 491, I-10126 Turin, Italy) V.1- 1909- Volume(issue)/page/year: 52,1789,1961
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 974 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 81,17,1944
其他信息
- 无臭或几乎无臭，味苦涩，有吸湿性，该品在水中易溶，在乙醇中略溶。
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