7-Hydroxychlorpromazine

CAS 2095-62-7 MFCD01706957

化学结构图

2095-62-7
SMILES: CN(C)CCCN1c2ccc(O)cc2Sc2ccc(Cl)cc21

化学属性

Mol. FormulaC17H19ClN2OS
Mol. Weight334.89

别名和识别编码

Chemical NamePhenothiazine,2-chloro-10-(3-(dimethylamino)propyl)-7-hydroxy-
Chemical Name Translation
Wiswesser Line NotationT C666 BN ISJ B3N1&1 EG LQ
Synonym 7-Hydroxychlorpromazine 7-hydroxychlorpromazine 7-hydroxychlorpromazine monohydrochloride
Beilstein Registry Number1021503
CAS Number2095-62-7
PubChem Substance ID16414
InChIInChI=1S/C17H19ClN2OS/c1-19(2)8-3-9-20-14-6-5-13(21)11-17(14)22-16-7-4-12(18)10-15(16)20/h4-7,10-11,21H,3,8-9H2,1-2H3
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安全信息

RTECSSO0175000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 119 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
   Lungs, Thorax, or Respiration - respiratory depression
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   JPMSAE Journal of Pharmaceutical Sciences.  (American Pharmaceutical Assoc.,
   2215 Constitution Ave., NW, Washington, DC 20037)  V.50-    1961-
   Volume(issue)/page/year: 62,715,1973

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   LIFSAK Life Sciences.  (Pergamon Press Inc., Maxwell House, Fairview Park,
   Elmsford, NY 10523) V.1-8, 1962-69; V.14-    1974- Volume(issue)/page/year:
   4,2425,1965

Hazard statements
  • H302 Harmful if swallowed 吞食有害
Precautionary statements
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
  • P301+P317
  • P330 Rinse mouth. 漱口
  • P501 Dispose of contents/container to..… 处理内容物/容器.....

系列性分类

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