(2S,3S,4S,5R,6S)-6-((5,6-Dihydroxy-2-(4-Hydroxyphenyl)-4-Oxo-4H-Chromen-7-Yl)Oxy)-3,4,5-Trihydroxytetrahydro-2H-Pyran-2-Carboxylic Acid (2S,3S,4S,5R,6S)-6-((5,6-二羟基-2-(4-羟基苯基)-4-氧代-4H-苯并吡喃-7-基)氧基)-3,4,5 -三羟基四氢-2H-吡喃-2-羧酸
CAS 27740-01-8 MFCD01861503
化学结构图
SMILES: OC(=O)[C@H]1O[C@@H](OC2=CC3OC(=CC(=O)C=3C(O)=C2O)C2C=CC(O)=CC=2)[C@H](O)[C@@H](O)[C@@H]1O
化学属性
| Mol. Formula | C21H18O12 |
|---|---|
| Mol. Weight | 462 |
| Density | 1.81 |
别名和识别编码
| Chemical Name | (2S,3S,4S,5R,6S)-6-((5,6-Dihydroxy-2-(4-Hydroxyphenyl)-4-Oxo-4H-Chromen-7-Yl)Oxy)-3,4,5-Trihydroxytetrahydro-2H-Pyran-2-Carboxylic Acid |
|---|---|
| CAS Number | 27740-01-8 |
| Synonym | 4',5,6,7-Tetrahydroxyflavone 7-?-D-Glucopyranuronoside 5,6-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl-β-D-glucopyranosiduronic acid 5,6-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl-β-D-glucopyranosiduronic acid 7-(β-D-Glucopyranuronosyloxy)-5,6-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one Breviscapin Scutellarein-7-O-β-D-glucuronide 5,6-Dihydroxy-2-(p-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl ?-D-Glucopyranosiduronic Acid 7-(β-D-Glucopyranuronosyloxy)-5,6-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one Breviscapin Breviscapin, Scutellarein-7-O-β-D-glucuronide Scutellarein 7-?-D 灯盏花乙素,野黄芩甙 野黄芩苷 |
| MDL Number | MFCD01861503 |
| Beilstein Registry Number | 71779 |
| EC Number | 250-023-7 |
| Chemical Name Translation | (2S,3S,4S,5R,6S)-6-((5,6-二羟基-2-(4-羟基苯基)-4-氧代-4H-苯并吡喃-7-基)氧基)-3,4,5 -三羟基四氢-2H-吡喃-2-羧酸 |
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信息真实价格透明
资金保障
专业采购外包团队在线服务
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分类
- Alphabetical, Analytical Standards, Analytical/Chromatography, Betula, Chromatography, Flavonoids, Life Sciences Standards, Phytopharma Standards, S - Z, Standards by Plant Genus, Substance Classification
- {SNA} Alphabetical Index of Phytochemical Standards, Analytical Standards, Betula, Flavonoids, Phytochemical Standards, Phytochemical Standards by Plant Genus, S - Z, 分析/色谱
产品应用
- 灯盏花乙素为云南特有的菊科植物灯盏细辛中提取，灯盏花乙素具有改善脑循环，增加脑血流量，降低脑血管阻力，提高血脑屏障能透性，增加营养性心肌血流量，提高巨噬细胞吞噬免疫功能作用，以及对抗由二磷酸腺苷引起的血小板凝聚作用。
相关文献及参考
- Gao, C. et al.: Drug Metab. Dispos., 39, 2034 (2011); Chan, J.Y. et al.: Anticancer Res., 29, 3043 (2009); Wang, C.-Z. et al.: Phytomedicine, 17, 63 (2010);
- Pan, Z., et al. , Scutellarin alleviates interstitial fibrosis and cardiac dysfunction of infarct rats by inhibiting TGFβ1 expression and activation of p38-MAPK and ERK1/2. Br. J. Pharmacol. 162 , 688-700, (2011)
- Li, H., et al. , Scutellarin inhibits cell migration by regulating production of ανβ6 integrin and E-cadherin in human tongue cancer cells. Oncol. Rep. 24 , 1153-1160, (2010)
- Hu, X.M., et al ., Neuroprotective effects of scutellarin on rat neuronal damage induced by cerebral ischemia/reperfusion. Acta Pharmacol. Sin. 26 , 1454-1459, (2005)
安全信息
GHS Symbol
- S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛，皮肤或衣服。
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