GLP-1R agonist

CAS 281209-71-0 MFCD81209710

化学结构图

281209-71-0
SMILES:

化学属性

Mol. Weight348.25
Mol. FormulaC13H15Cl2N3O2S

别名和识别编码

Synonym 2-Quinoxalinamine, 6,7-dichloro-N-(1,1-dimethylethyl)-3-(methylsulfonyl)- 2-Quinoxalinamine, 6,7-dichloro-N-(1,1-dimethylethyl)-3-(methylsulfonyl)- 6,7-dichloro-2-methylsulfonyl-3-N-tert-butylaminoquinoxaline (DMB) Compound 2 6,7-dichloro-2-methylsulfonyl-3-N-tert-butylaminoquinoxaline (DMB) Compound 2
CAS Number281209-71-0
Chemical NameGLP-1R agonist
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分类

  • Cell Biology, Cell Signaling and Neuroscience, Cytokines, Growth Factors and Hormones, Hormones, Insulin and Insulin Receptors, Other Protein/Peptide Hormones
  • {SNA} Bioactive Small Molecule Alphabetical Index, Cytokines, Growth Factors and Hormones, G, Hormones, Insulin and Insulin Receptors, Other Protein/Peptide Hormones,

相关文献及参考

  • Irwin, N., et al., Insulin-releasing and metabolic effects of small molecule GLP-1 receptor agonist 6,7-dichloro-2-methylsulfonyl-3-N-tert-butylaminoquinoxaline. Eur. J. Pharmacol. 1-3 , 268-273, (2010) 摘要
  • Koole, C., et al., Allosteric ligands of the glucagon-like peptide 1 receptor (GLP-1R) differentially modulate endogenous and exogenous peptide responses in a pathway-selective manner; implications for drug screening. Mol. Pharmacol. , (2010)
  • Teng, M., et al., Small molecule ago-allosteric modulators of the human glucagon-like peptide-1 (hGLP-1) receptor. Bioorg. Med. Chem. Lett. 19 , 5472-5478, (2007) 摘要

安全信息

GHS Symbol
Signal word Warning
Hazard statements
  • H302 Harmful if swallowed 吞食有害
WGK Germany3
Hazard Codes Xn
Risk Statements
  • R22 Harmful if swallowed 吞咽有害

系列性分类


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