Spermine Tetrahydrochloride 精胺四盐酸盐

CAS 306-67-2 MFCD00012914

化学结构图

306-67-2
SMILES: Cl.Cl.Cl.Cl.NCCCNCCCCNCCCN

化学属性

Mol. FormulaC10H30Cl4N4
Mol. Weight348.18
Melting Point310-311 °C
Density1.01 g/mL at 20 °C
TSCAYes
SolubilityH2O: 1 M at 20 °C, clear, colorless
Appearance 黄色或淡黄色油状液体。 powder
Flash Point>;230 °F
Boiling Point150 °C5 mm Hg(lit.)

别名和识别编码

Chemical NameSpermine Tetrahydrochloride
MDL NumberMFCD00012914
CAS Number306-67-2
Synonym Spermine (tetrahydrochloride) {LY} Spermine (tetrahydrochloride) {} {LY} Spermine (tetrahydrochloride) {} {} {LY} Spermine (tetrahydrochloride) {} {} {} {LY} Spermine (tetrahydrochloride) {} {} {} {} {LY} Spermine (tetrahydrochloride) {} {} {} {} {} {LY} Spermine (tetrahydrochloride) {} {} {} {} {} {} {LY} Spermine (tetrahydrochloride) {} {} {} {} {} {} {} {LY} Spermine (tetrahydrochloride) {} {} {} {} {} {} {} {} {LY} Spermine (tetrahydrochloride) {} {} {} {} {} {} {} {} {} {LY} Spermine (tetrahydrochloride) {} {} {} {} {} {} {} {} {} {} {LY} Spermine (tetrahydrochloride) {} {} {} {} {} {} {} {} {} {} {} {LY} Spermine (tetrahydrochloride) {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Spermine (tetrahydrochloride) {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Spermine (tetrahydrochloride) {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Spermine (tetrahydrochloride) {} {} {} {} {} {} {} {} {}
PubChem Substance ID87564385
EC Number206-189-8
Beilstein Registry Number3911771
Reaxys-RN3911771
Chemical Name Translation精胺四盐酸盐
Merck Number14,8743
Wiswesser Line NotationZ3M4M3Z 4GH
LabNetwork Molecule IDLN01360413
InChIInChI=1S/C10H26N4.4ClH/c11-5-3-9-13-7-1-2-8-14-10-4-6-12;;;;/h13-14H,1-12H2;4*1H
Canonical SMILESNCCCNCCCCNCCCN.Cl.Cl.Cl.Cl
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分类

  • {SNA} Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Enzyme Inhibitors, Enzyme Inhibitors by Type, Enzymes, Inhibitors, and Substrates, S, Substrate Analogs
  • {SNA} Amino Acid,
  • {SNA} Bioactive Small Molecules, Cell Biology,
  • {SNA} BioUltra, Bioactive Small Molecules, DNA & RNA Purification, Molecular Biology, Molecular Biology Reagents, Reagents, S, 细胞生物学
  • {SNA} DNA和RNA纯化, Reagents, 分子生物学, 植物分子生物学, 植物核酸纯化, 植物生物技术, 试剂
  • {SNA} BioUlt
  • {SNA} Bioactive Small Molecule Alphabetical Index,

安全信息

GHS Symbol
WGK Germany3
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
RTECSEJ7230000
Precautionary statements
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P350
  • P302+P352+P332+P313+P362+P364
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P332+P313
  • P337+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
Signal word Warning
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S37 Wear suitable gloves 戴适当手套;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
Risk Statements
  • R34 Causes burns 会导致灼伤
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R36/38 Irritating to eyes and skin 对眼睛和皮肤有刺激性
Hazard Codes Xi,C Xi
Storage condition RT, protect from light {LY} RT, protect from light {} {LY} RT, protect from light {} {} {LY} RT, protect from light {} {} {} {LY} RT, protect from light {} {} {} {} {LY} RT, protect from light {} {} {} {} {} {LY} RT, protect from light {} {} {} {} {} {} {LY} RT, protect from light {} {} {} {} {} {} {} {LY} RT, protect from light {} {} {} {} {} {} {} {} {LY} RT, protect from light {} {} {} {} {} {} {} {} {} {LY} RT, protect from light {} {} {} {} {} {} {} {} {} {} {LY} RT, protect from light {} {} {} {} {} {} {} {} {} {} {} {LY} RT, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {LY} RT, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} RT, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} RT, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} RT, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} RT, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} RT, protect
Packing GroupIII
Hazard Class8
UN Number UN 3259 8/PG 2
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 370 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - changes in motor activity (specific assay)
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   FEPRA7 Federation Proceedings, Federation of American Societies for
   Experimental Biology. (Bethesda, MD)  V.1-46, 1942-87.
   Volume(issue)/page/year: 41,1575,1982

TYPE OF TEST            : DNA adduct
TEST SYSTEM             : Bacteria - Serratia marcescens
DOSE/DURATION           : 8900 nmol/L
REFERENCE :
   BIPMAA Biopolymers.  (John Wiley & Sons, Inc., 605 Third Ave., New York, NY
   10158)  V.1-    1963-  Volume(issue)/page/year: 5,227,1967

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Human HeLa cell
DOSE/DURATION           : 2 mmol/L
REFERENCE :
   JCLLAX Journal of Cellular Physiology.  (Alan R. Liss, Inc., 41 E. 11th St.,
   New York, NY 10003) V.67-    1966-  Volume(issue)/page/year: 78,217,1971

TYPE OF TEST            : DNA adduct
TEST SYSTEM             : Microorganism - not otherwise specified
DOSE/DURATION           : 8900 nmol/L
REFERENCE :
   BIPMAA Biopolymers.  (John Wiley & Sons, Inc., 605 Third Ave., New York, NY
   10158)  V.1-    1963-  Volume(issue)/page/year: 5,227,1967

TYPE OF TEST            : DNA adduct
TEST SYSTEM             : Mammal - species unspecified Lymphocyte
DOSE/DURATION           : 16700 nmol/L
REFERENCE :
   BIPMAA Biopolymers.  (John Wiley & Sons, Inc., 605 Third Ave., New York, NY
   10158)  V.1-    1963-  Volume(issue)/page/year: 5,227,1967

TYPE OF TEST            : DNA adduct
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 8900 nmol/L
REFERENCE :
   BIPMAA Biopolymers.  (John Wiley & Sons, Inc., 605 Third Ave., New York, NY
   10158)  V.1-    1963-  Volume(issue)/page/year: 5,227,1967

其他信息

  • 上游原料:椰子油
  • Alfa Aesar:精胺;精素,97% Spermine, 97%(71-44-3)
  • Sigma Aldrich:71-44-3(sigmaaldrich)
  • 用途一:可作为有机磷农药中间体。同时,是典型的阴离子表面活性剂,具有良好的渗透、乳化、泡沫和去污能力,广泛应用于化工,农药、纤维、电渡、选矿等工业,尤其适用于化妆品、牙膏、香波等的制造。纺织工业中适用于洗涤羊毛和丝绸。
  • 图谱信息:精胺(306-67-2)核磁图( 1 HNMR) 精胺(306-67-2)核磁图( 13 CNMR) 精胺(306-67-2)质谱(MS) 精胺(306-67-2)红外图谱(IR2) 精胺(306-67-2)红外图谱(IR1)
  • MOL 文件:71-44-3.mol
  • F:3-10
  • Acros Organics:精胺/O,O-二甲基硫代磷酰胺 Spermine, 97%(71-44-3)
  • MOL 文件:306-67-2.mol
  • 方法一:以椰子油为原料制得的脂肪醇,经硫酸磺化制得。
  • 敏感性:Air Sensitive & Hygroscopic
  • TCI Shanghai:N,N'-二(3-胺丙基)-1,4-丁二胺四盐酸盐 N,N'-Bis(3-aminopropyl)-1,4-butanediamine Tetrahydrochloride,>;98.0%(T)(306-67-2)
  • 精胺价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 B1468 N,N'-双(3-胺丙基)-1,4-丁二胺四盐酸盐 N,N'-Bis(3-aminopropyl)-1,4-butanediamine Tetrahydrochloride 5G 1630元 2014/06/02 B1468 N,N'-双(3-胺丙基)-1,4-丁二胺四盐酸盐 N,N'-Bis(3-aminopropyl)-1,4-butanediamine Tetrahydrochloride 25G 5640元
  • 存储注意事项:氮气保护
  • 精胺价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 K8559001 精胺(+4℃) 5g 2189元 2010/06/21 132752500 精胺 Spermine 97% 250 MG 249元 2010/06/21 132750010 精胺 Spermine 97% 1 GR 612元
  • Sigma Aldrich:306-67-2(sigmaaldrich)
  • 图谱信息:精胺(71-44-3)红外图谱(IR1)

系列性分类


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