4-[5-[(2-ETHOXY-5-PYRIMIDINYL)METHYL]-2-[[(4-FLUOROPHENYL)METHYL]THIO]-4-OXO-1(4H)-PYRIMIDINYL]-BENZOIC ACID ETHYL ESTER

CAS 306974-70-9 MFCD09953714

化学结构图

306974-70-9
SMILES: CCOC1N=CC(CC2=CN(C(=NC2=O)SCC2C=CC(F)=CC=2)C2C=CC(=CC=2)C(=O)OCC)=CN=1

化学属性

Mol. FormulaC27H25FN4O4S
Mol. Weight520.583

别名和识别编码

Chemical Name4-[5-[(2-ETHOXY-5-PYRIMIDINYL)METHYL]-2-[[(4-FLUOROPHENYL)METHYL]THIO]-4-OXO-1(4H)-PYRIMIDINYL]-BENZOIC ACID ETHYL ESTER
Chemical Name Translation
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

相关文献及参考

  • [2]. Briscoe CP, et al. Pharmacological regulation of insulin secretion in MIN6 cells through the fatty acid receptor GPR40: identification of agonist and antagonist small molecules. Br J Pharmacol. 2006 Jul;148(5):619-28.
  • [3]. Manosalva C, et al. Cloning, identification and functional characterization of bovine free fatty acid receptor-1 (FFAR1/GPR40) in neutrophils. PLoS One. 2015 Mar 19;10(3):e0119715.
  • [4]. Nakamoto K, et al. Hypothalamic GPR40 signaling activated by free long chain fatty acids suppresses CFA-induced inflammatorychronic pain. PLoS One. 2013 Dec 12;8(12):e81563.
  • [1]. Stoddart LA, et al. Uncovering the pharmacology of the G protein-coupled receptor GPR40: high apparent
  • [1]. Stoddart LA, et al. Uncovering the pharmacology of the G protein-coupled receptor GPR40: high apparent constitutive activity in guanosine 5'-O-(3-[35S]thio)triphosphate binding studies reflects binding of an endogenous agonist. Mol Pharmacol. 2007 Apr;71(

系列性分类

  1. Medical Research Areas
  2. GPCR & G Protein
  3. GPR40  (G蛋白偶联受体40)

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