Bupropion hydrochloride 盐酸安非他酮(精神管制药品，不能销售）
CAS 31677-93-7 MFCD00055209
化学结构图
SMILES: Cl.CC(NC(C)(C)C)C(=O)C1C=CC=C(Cl)C=1
化学属性
| Mol. Formula | C13H19Cl2NO |
|---|---|
| Mol. Weight | 276 |
| TSCA | No |
| Melting Point | 222 |
别名和识别编码
| Chemical Name | Bupropion hydrochloride |
|---|---|
| CAS Number | 31677-93-7 |
| Alfabeta Name | BUPROPIONHYDROCHLORIDE |
| MDL Number | MFCD00055209 |
| Synonym | 2-(tert-Butylamino)-1-(3-chlorophenyl)-1-propanone Hydrochloride, Amfebutamone Hydrochloride Bupropion hydrochloride |
| PubChem Substance ID | 125307968 |
| EC Number | 250-759-9 |
| Merck Number | 1499 |
| Chemical Name Translation | 盐酸安非他酮(精神管制药品，不能销售） |
| Reaxys-RN | 6161273 |
| Beilstein Registry Number | 6161273 |
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信息真实价格透明
资金保障
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分类
- {SNA} Approved Therapeutics/Drug Candidates, B, Bioactive Small Molecules, Biochemicals and Reagents, Biogenic Amine Transport Inhibitors, Cell Biology, Cell Signaling and Neuroscience, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, GlaxoSmithKline, Membrane Protein Biology Tools, Neuroscience, Neurotransmission, Neurotransmission (Obesity), Neurotransmitters, Obesity Research, Proteins and Derivatives
- {SNA} Analytical Standards, Pharmacopeia & Metrological Institutes Standards, USP Standards, USP Standards A - B, 分析/色谱
安全信息
GHS Symbol
- H302 Harmful if swallowed 吞食有害
- S36 Wear suitable protective clothing 穿戴适当的防护服；
- R22 Harmful if swallowed 吞咽有害
- P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
- P301+P312+P330
TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Human - man DOSE/DURATION : 329 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Cardiac - pulse rate Cardiac - other changes REFERENCE : JTCTDW Journal of Toxicology, Clinical Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.19- 1982- Volume(issue)/page/year: 35,321,1997
TYPE OF TEST : LD50 - Lethal dose, 50 perce
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 210 mg/kg TOXIC EFFECTS : Behavioral - tremor Behavioral - muscle contraction or spasticity REFERENCE : JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 29,767,1977
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 230 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - changes in motor activity (specific assay) Behavioral - analgesia REFERENCE : JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 29,767,1977
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Human - woman DOSE/DURATION : 2 mg/kg TOXIC EFFECTS : Behavioral - hallucinations, distorted perceptions Behavioral - food intake (animal) Gastrointestinal - nausea or vomiting REFERENCE : AJPSAO American Journal of Psyc
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