Phosphocysteamine sodium 半胱胺S-磷酸钠盐

CAS 3724-89-8 MFCD00038474

化学结构图

3724-89-8
SMILES: NCCSP(=O)(O)O.[NaH]

化学属性

Mol. FormulaC2H7NNaO3PS
Mol. Weight179.11
Melting Point220 °C

别名和识别编码

Chemical NamePhosphocysteamine sodium
Synonym Cysteamine S-phosphate (sodium) {LY} Cysteamine S-phosphate (sodium) Phosphocysteamine Salt beta-Aminoethylthiophosphate, Sodium Sodium Salt beta-Aminoethylthiophosphate WR 638 WR-638 WR638 beta Aminoethylthiophosphate, Sodium Salt beta-Aminoethylthiophosphate, Sodium Salt {} {LY} Cysteamine S-phosphate (sodium) {} {} {LY} Cysteamine S-phosphate (sodium) {} {} {} {LY} Cysteamine S-phosphate (sodium) {} {} {} {} {LY} Cysteamine S-phosphate (sodium) {} {} {} {} {} {LY} Cysteamine S-phosphate (sodium) {} {} {} {} {} {} {LY} Cysteamine S-phosphate (sodium) {} {} {} {} {} {} {} {LY} Cysteamine S-phosphate (sodium) {} {} {} {} {} {} {} {} {LY} Cysteamine S-phosphate (sodium) {} {} {} {} {} {} {} {} {} {LY} Cysteamine S-phosphate (sodium) {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {LY} Cysteamine S-phosphate (sodium) {} {} {} {} {} {} {} {} {} {} {} {LY} Cysteamine S-
MDL NumberMFCD00038474
PubChem Substance ID23664253
CAS Number3724-89-8
EC Number223-079-5
Chemical Name Translation半胱胺S-磷酸钠盐
Wiswesser Line NotationZ2SPQO&O &-NA-
Canonical SMILESO=P(SCCN)(O[Na])O
InChIInChI=1S/C2H8NO3PS.Na/c3-1-2-8-7(4,5)6;/h1-3H2,(H2,4,5,6);/q;+1/p-1
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分类

  • {SA} Alphabetic, Analytical Standards, Analytical/Chromatography, C, CO - CZ, Chemical Structure, Chromatography, Drugs & Metabolites, Drugs of Abuse, Forensic and Veterinary Standards, Neat Compounds, Others
  • Alphabetic, Analytical Standards, Analytical/Chromatography, C, CO - CZ, Chemical Structure, Chromatography, Drugs & Metabolites, Drugs of Abuse, Forensic and Veterinary Standards, Neat Compounds, Others
  • {SNA} Alphabetical Index of Analytical Standards, Analytical Standards, C

相关文献及参考

  • Neumann, H., et al. Br. J. Haematol. 41 , 519, (1979) 摘要
  • Merck 14 ,7341

安全信息

RTECSTE6483500
WGK Germany3
GHS Symbol
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P264+P265
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P312
  • P301+P317
  • P302+P352
  • P304+P340
  • P305+P351+P338
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
  • P319
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P330 Rinse mouth. 漱口
  • P332+P313
  • P332+P317
  • P337+P313
  • P337+P317
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P362+P364
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H302 Harmful if swallowed 吞食有害
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Hazard Codes Xn
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Signal word Warning
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R22 Harmful if swallowed 吞咽有害
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 806 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   RADOA8 Radiobiologiya.  (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-    1961-  Volume(issue)/page/year: 16,249,1976

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 358 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   RADOA8 Radiobiologiya.  (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-    1961-  Volume(issue)/page/year: 16,249,1976

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1003 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   RADOA8 Radiobiologiya.  (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-    1961-  Volume(issue)/page/year: 16,249,1976

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 505 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1433 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   RADOA8 Radiobiologiya.  (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-    1961-  Volume(issue)/page/year: 16,2

Storage condition

系列性分类


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