RepSox ALK 5抑制剂II

CAS 446859-33-2 MFCD09037561

化学结构图

446859-33-2
SMILES:

化学属性

Mol. FormulaC17H13N5
Mol. Weight287.32

别名和识别编码

Chemical NameRepSox
Synonym E-616452; 2-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]-1,5-naphthyridine RepSox
MDL NumberMFCD09037561
CAS Number446859-33-2
PubChem Substance ID329823975
Chemical Name TranslationALK 5抑制剂II
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分类

  • {SNA} Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Cytokines and Growth Factors, Cytokines, Growth Factors and Hormones, R, TGF-β Inhibitors, Transforming Growth Factor-β (TGF-β) and Superfamily
  • {SA} Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Cytokines and Growth Factors, Cytokines, Growth Factors and Hormones, R, TGF-β Inhibitors, Transforming Growth Factor-β (TGF-β) and Superfamily
  • {SNA} Bioactive Small Molecule Alphabetical Index, Cytokines and Growth Factors, Cytokines, Growth Factors and Hormones, R, TGF-β Inhibitors, Transforming Growth Factor-β (TGF-β) and Superfamily, 生物活性小分子,

相关文献及参考

  • Gellibert, F., et al., Design of novel quinazoline derivatives and related analogues as potent and selective ALK5 inhibitors. Bioorg. Med. Chem. Lett. 19 , 2277-81, (2009) 摘要
  • Gellibert, F., et al., Identification of 1,5-naphthyridine derivatives as a novel series of potent and selective TGF-beta type I receptor inhibitors. J. Med. Chem. 47 , 4494-506, (2004) 摘要

安全信息

GHS Symbol
Precautionary statements
  • P301+P310+P330
  • P301+P310
Signal word Danger
Hazard statements
  • H301 Toxic if swallowed 吞食有毒
Safety Statements
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
Hazard Codes T
Risk Statements
  • R25 Toxic if swallowed 吞咽有毒
WGK Germany3

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Cytokines, Growth Factors and Hormones - Cell Signaling and Neuroscience
  5. Cytokines and Growth Factors - Cytokines, Growth Factors and Hormones
  6. Transforming Growth Factor-β (TGF-β) and Superfamily - Cytokines and Growth Factors
  7. TGF-β Inhibitors - Transforming Growth Factor-β (TGF-β) and Superfamily

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