6-Ethoxybenzo[d]thiazole-2-sulfonamide 依索唑胺
CAS 452-35-7 MFCD00057089
化学结构图
SMILES: CCOc1ccc2nc(S(N)(=O)=O)sc2c1
化学属性
| Mol. Formula | C9H10N2O3S2 |
|---|---|
| Mol. Weight | 258 |
| Melting Point | 190-193 °C(lit.) |
别名和识别编码
| Chemical Name | 6-Ethoxybenzo[d]thiazole-2-sulfonamide |
|---|---|
| Synonym | {uni_hamburg} Diuretic C Cardrase 6-Ethoxy-2-benzothiazolesulfonamide PNU 4191 2-Benzothiazolesulfonamide, 6-ethoxy- 6-ethoxy-2-benzothiazole sulfonamide 6-ethoxybenzothiazole-2-sulfonamide Ethoxyzolamide glaucotensil Etoxzolamide 6-Ethoxy-2-benzothiazolsulfonamid Ethoxzolamide 6-ethoxybenzo[d]thiazole-2-sulfonamide Ethamide L 643786 6-乙氧基-2-苯并噻唑磺酰胺 依索唑胺 U-4191 乙氧苯噻唑胺 ethoxozolamide 6-ethoxybenzothiazole-2-sulphonamide Ethoxazolamide 6-ethoxy-2-benzothiazolesulfonamide |
| MDL Number | MFCD00057089 |
| CAS Number | 452-35-7 |
| PubChem Substance ID | 3295 |
| EC Number | 207-199-5 |
| Chemical Name Translation | 依索唑胺 |
| Wiswesser Line Notation | T56 BN DSJ CSZW GO2 |
| Beilstein Registry Number | 0212240 |
| InChI | InChI=1S/C9H10N2O3S2/c1-2-14-6-3-4-7-8(5-6)15-9(11-7)16(10,12)13/h3-5H,2H2,1H3,(H2,10,12,13) |
信息真实价格透明
资金保障
专业采购外包团队在线服务
信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- {SNA} Bioactive Small Molecules, Building Blocks, C8 to C9, Chemical Synthesis, E, Heterocyclic Building Blocks, Thiazoles, 细胞生物学
- {uni_hamburg} no charge; sulfur heterocycle; nitrogen heterocycle; carbocycle; aromatic; large ring; fused rings; 5ring; 6ring; 9ring; ether; 1fragment
- {SNA} Building Blocks, C8 to C9, Chemical Synthesis, Heterocyclic Building Blocks, Thiazoles
- {SNA} Bioactive Small Molecules, Building Blocks, C8 to C9, Cell Biology, Chemical Synthesis, E, Heterocyclic Building Blocks, Thiazoles
相关文献及参考
- [2]. Benjamin K. Johnson, et al. The Carbonic Anhydrase Inhibitor Ethoxzolamide Inhibits theMycobacterium tuberculosis PhoPR Regulon and Esx-1 Secretion and Attenuates Virulence. Antimicrob Agents Chemother. 2015 Aug; 59(8): 4436–4445.
- [3]. Song Gao, et al. Development and validation of an UPLC-MS/MS method for the quantification of ethoxzolamide in plasma and bioequivalent buffers: Applications to absorption, brain distribution, and pharmacokinetic studies. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Apr 1; 0: 54–59.
- Short: EINECS Title: EINECS (European Inventory of Existing Commercial Chemical Substances) Source: Official Journal of the European Communities Volume: C 146 A (15.06.1990) Page: 1 Year: 1990 Internet Resource: http://ecb.jrc.ec.europa.eu/esis/index.php?PGM=ein Publish_Date: 1990/06/15
- Short: IV/8A Title: Enthalpies of Fusion and Transition of Organic Compounds Author: Zhang, Z.-Y.; Frenkel, M.; March, K.N.; Wilhoit
安全信息
GHS Symbol
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P305+P351+P338
- H315 Causes skin irritation 会刺激皮肤
- H319 Causes serious eye irritation 严重刺激眼睛
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE : 3300 mg/kg SEX/DURATION : female 1-22 day(s) after conception TOXIC EFFECTS : Reproductive - Specific Developmental Abnormalities - musculoskeletal system Reproductive - Effects on Embryo or Fetus - fetal death Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) REFERENCE : TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 1,51,1968
京ICP备2020036287号