DL-Carnitine Hydrochloride DL-肉碱盐酸盐

CAS 461-05-2 MFCD00011904

化学结构图

461-05-2
SMILES: [Cl-].C[N+](C)(C)CC(O)CC(O)=O

化学属性

Mol. FormulaC7H16ClNO3
Mol. Weight197.66
Melting Point197-199°C
TSCAYes
Solubility可溶
Stability易吸潮
Appearance 白色结晶性粉末，溶于水和乙醇，容易吸湿。

别名和识别编码

Chemical NameDL-Carnitine Hydrochloride
MDL NumberMFCD00011904
CAS Number461-05-2
Synonym (±)-Carnitine (chloride) (±)-Carnitine (chloride) (Levocarnitine Impurity) {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
Beilstein Registry Number4163212
EC Number207-309-1
Merck Number1849
PubChem Substance ID87565252
Reaxys-RN5627963
Chemical Name TranslationDL-肉碱盐酸盐
LabNetwork Molecule IDLN00224776
Canonical SMILESC[N+](C)(C)CC(O)CC(O)=O.[Cl-]
信息真实价格透明    资金保障    专业采购外包团队在线服务   
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分类

  • {SNA} A - H, Amino Acids, Modified Amino Acids, 生化试剂
  • {SNA} A - H, Amino Acids, Biochemicals and Reagents, Modified Amino Acids

相关文献及参考

  • [2]. Li J, et al. l-carnitine protects human hepatocytes from oxidative stress-induced toxicity through Akt-mediated activation of Nrf2 signaling pathway. Can J Physiol Pharmacol. 2016 May;94(5):517-25.
  • [3]. Jang J, et al. l-Carnitine supplement reduces skeletal muscle atrophy induced by prolonged hindlimb suspension in rats. Appl Physiol Nutr Metab. 2016 Dec;41(12):1240-1247.
  • [4]. Zambrano S, et al. L-carnitine attenuates the development of kidney fibrosis in hypertensive rats by upregulating PPAR-γ. Am J Hypertens. 2014 Mar;27(3):460-70.
  • [1]. Oyanagi E, et al. Protective action of L-carnitine on cardiac mitochondrial function and structure against fatty acidstress. Biochem Biophys Res Commun. 2011 Aug 19;412(1):61-7.
  • [1]. Oyanagi E, et al. Protective action of L-carnitine on cardiac mitochondrial function and structure against fatty acidstress. Biochem Biophys Res Commun. 2011 Aug 19;412(1):61-7.
  • [2]. Li J, et al. l-carnitine prote

安全信息

GHS Symbol
WGK Germany3
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P352+P332+P313+P362+P364
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
RTECSBP2979140
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Signal word Warning
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36 Wear suitable protective clothing 穿戴适当的防护服；
  • S37 Wear suitable gloves 戴适当手套；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Storage condition 2-8°C Hygroscopic
Hazard Codes Xi 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 10 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ABMGAJ Acta Biologica et Medica Germanica.  (Berlin, Ger. Dem. Rep.) V.1-41,
   1958-82.  For publisher information, see BBIADT. Volume(issue)/page/year:
   3,28,1959

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 6 gm/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - fluid intake
   Lungs, Thorax, or Respiration - cyanosis
REFERENCE :
   ABMGAJ Acta Biologica et Medica Germanica.  (Berlin, Ger. Dem. Rep.) V.1-41,
   1958-82.  For publisher information, see BBIADT. Volume(issue)/page/year:
   3,28,1959

其他信息

  • 可燃性危险特性:热分解排出有毒氮氧化物, 氯化物烟雾
  • 类别:有毒物质
  • 图谱信息:混旋肉碱盐酸盐(461-05-2)核磁图( 1 HNMR) 混旋肉碱盐酸盐(461-05-2)红外图谱(IR1) 混旋肉碱盐酸盐(461-05-2)红外图谱(IR2) 混旋肉碱盐酸盐(461-05-2)核磁图( 13 CNMR) 混旋肉碱盐酸盐(461-05-2)质谱(MS)
  • Sigma Aldrich:461-05-2(sigmaaldrich)
  • 用途一:用于医药、水产饲料添加营养剂等
  • 海关编码:29239000
  • MSDS 信息:DL-Carnitine hydrochloride(461-05-2).msds
  • 上游原料:盐酸 --> 甲醇 --> 环氧氯丙烷 --> 三甲胺
  • 混旋肉碱盐酸盐价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 C0050 DL-肉碱盐酸盐 DL-Carnitine Hydrochloride 500G 1160元 2014/06/02 C0050 DL-肉碱盐酸盐 DL-Carnitine Hydrochloride 25G 159元 2010/06/21 108450250 混旋肉碱盐酸盐 DL-Carnitine hydrochloride 99% 25 GR 264元
  • 敏感性:Hygroscopic
  • 灭火剂:水,二氧化碳, 泡沫, 干粉
  • TCI Shanghai:DL-肉碱盐酸盐 DL-Carnitine Hydrochloride,>;98.0%(T)(461-05-2)
  • Alfa Aesar:DL-肉碱盐酸盐,98+% DL-Carnitine hydrochloride, 98+%(461-05-2)
  • 储运特性:库房低温通风干燥
  • 急性毒性:皮下-大鼠 LD50: 10000 毫克/公斤; 皮下-小鼠 LD50: 6000 毫克/公斤
  • MOL 文件:461-05-2.mol
  • 毒性分级:低毒
  • Acros Organics:DL-肉碱盐酸盐 DL-Carnitine hydrochloride, 99%(461-05-2)

系列性分类

  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Amino Acids 氨基酸
  4. Modified Amino Acids - Amino Acids
  5. A - H - Modified Amino Acids
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Amino Acids 氨基酸
  4. Modified Amino Acids - Amino Acids
  5. A - H - Modified Amino Acids
  1. Chemical Synthesis 化学合成
  2. Chemical Biology 生物化学
  3. Peptide Chemistry 多肽化学
  4. Unnatural Amino Acid Derivatives 人工合成氨基酸
  5. Others - Unnatural Amino Acid Derivatives
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Amino Acids 氨基酸
  4. Other Amino Acids
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Chemicals by Class 化学分类法
  4. Quaternary Ammonium Compounds 季铵化合物
  1. Functional Group 官能团索引
  2. quaternary ammonium salt
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Albumins and Transport Proteins
  4. Albumin
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Amino Acids
  4. Amino Acids
  1. Medical Research Areas
  2. Metabolism
  3. Reactive Oxygen Species  (活性氧)

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