Phenothiazine, 10-(2-(dimethylamino)ethyl)-

CAS 522-24-7 MFCD00865683

化学结构图

522-24-7
SMILES: CN(C)CCN1c2ccccc2Sc2ccccc21

化学属性

Mol. FormulaC16H18N2S
Mol. Weight270.42

别名和识别编码

Chemical NamePhenothiazine, 10-(2-(dimethylamino)ethyl)-
Synonym Anergell 10-(beta-Dimethylaminoethyl)phenothiazine Anergen Etisin Phenethazine N,N-Dimethyl-10H-phenothiazine-10-ethanamine Ethysene Ethizine Lysergan Phenethazinum SC 1627 10-(2-Dimethylaminoethyl)phenothiazine RP 3015 Phenetazine Etisine Ethyzine Ethysine Parkazin Rutergan Lisergan
Wiswesser Line NotationT C666 BN ISJ B2N1&1
CAS Number522-24-7
PubChem Substance ID68223
InChIInChI=1S/C16H18N2S/c1-17(2)11-12-18-13-7-3-5-9-15(13)19-16-10-6-4-8-14(16)18/h3-10H,11-12H2,1-2H3
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安全信息

RTECSSO5250000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 190 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   RPTOAN Russian Pharmacology and Toxicology (English Translation).
   Translation of FATOAO.  (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey,
   UK)  V.30-    1967-  Volume(issue)/page/year: 31,53,1968

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 364 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 8,489,1958

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 115 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 4,171,1954

系列性分类

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