L-Nmma Acetate N-单甲基-L-精氨酸单乙酸盐

CAS 53308-83-1 MFCD00069311

化学结构图

53308-83-1
SMILES: CC(O)=O.CNC(=N)NCCC[C@H](N)C(O)=O

化学属性

Mol. FormulaC9H20N4O4
Mol. Weight248

别名和识别编码

Chemical NameL-Nmma Acetate
CAS Number53308-83-1
Synonym ANO 1020 L-NMMA Nω-Methyl-L-arginine acetate salt Nω-Methyl-L-arginine acetate salt L-NMMA N5-(Methylamidino)-L-ornithine acetate salt NG-Monomethyl-L-arginine acetate salt N5-(Methylamidino)-L-ornithine acetate salt N5-[Imino(methylamino)methyl]-L-ornithine Acetate NG-Methyl-L-arginine acetate salt NG-Monomethyl-L-arginine acetate salt Tilarginine Acetate
MDL NumberMFCD00069311
PubChem Substance ID87573320
Beilstein Registry Number6674255
Reaxys-RN6674255
Merck Number6022
Chemical Name TranslationN-单甲基-L-精氨酸单乙酸盐
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分类

  • Application Index, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling Enzymes, Cell Signaling and Neuroscience, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, L to O, M, NOS Inhibitors, Nitric Oxide Metabolism, Nitric Oxide Synthase (iNOS), Nitric Oxide Synthase Regulators, Nitric Oxide and Cell Stress, Peptides and Proteins, Peptides for Cell Biology
  • {SNA} Application Index, Bioactive Small Molecule Alphabetical Index, Cell Signaling Enzymes, Enzyme Inhibitor
  • {SNA} Amino Acids, I - Z, Modified Amino Acids, 生化试剂

产品应用

  • A potent inhibitor of NO synthase of adrenal glands, brain, and vascular endothelial cells.

相关文献及参考

  • Rees, D.D., et al.: Br. J. Pharmacol., 101, 746 (1990),
  • McCall, T.B., et al.: Br. J. Pharmacol., 102, 234 (1991),
  • Sakuma, I., et al., Identification of arginine as a precursor of endothelium-derived relaxing factor. Proc. Natl. Acad. Sci. U. S. A. 85 , 8664-8667, (1988) 摘要
  • von Bargen, K., et al., Nitric Oxide-Mediated Intracellular Growth Restriction Of Pathogenic Rhodococcus Equi Can Be Prevented By Iron. Infect. Immun. 79 , 2098-111, (2011) 摘要
  • Butler, J.S., et al., Protein-arginine Methyltransferase 1 (PRMT1) Methylates Ash2L, A Shared Component Of Mammalian Histone H3K4 Methyltransferase Complexes. J. Thorac. Cardiovasc. Surg. 286 , 12234-44, (2011) 摘要
  • Merck 14 ,6022

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
RTECSRM2982000

系列性分类

  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Amino Acids 氨基酸
  4. Modified Amino Acids - Amino Acids
  5. I - Z - Modified Amino Acids
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Enzyme Inhibitors - Enzymes, Inhibitors, and Substrates
  5. Enzyme Inhibitors by Enzyme - Enzyme Inhibitors
  6. L to O - Enzyme Inhibitors by Enzyme
  7. Nitric Oxide Synthase (iNOS) - L to O
  1. Enzyme Inhibitors - Peptides for Cell Biology
  2. Nitric Oxide Synthase (iNOS) - Enzyme Inhibitors
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Albumins and Transport Proteins
  4. Albumin
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Amino Acids
  4. Amino Acids
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Cell Signaling and Neuroscience
  4. Nitric Oxide and Cell Stress
  5. Nitric Oxide Metabolism
  6. Nitric Oxide Scavengers
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Cell Signaling and Neuroscience
  4. Peptides and Proteins
  5. Enzyme Inhibitors
  6. Nitric Oxide Synthase
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Cell Signaling and Neuroscience
  4. Peptides and Proteins
  5. Peptides for Cell Biology
  6. Cathepsin/Granzyme Inhibitors & Substrates
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Enzymes, Inhibitors, and Substrates
  4. Cell Signaling Enzymes
  5. Nitric Oxide Metabolism
  6. NO Donors
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Enzymes, Inhibitors, and Substrates
  4. Enzyme Inhibitors
  5. Enzyme Inhibitors by Enzyme
  6. Nitric Oxide Synthase
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Peptides
  4. Peptides for Cell Biology
  5. Enzyme Inhibitors
  6. Nitric Oxide Synthase

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