2-Arachidonoyl Glycerol 2-Arachidonyl
CAS 53847-30-6 MFCD01862600
化学结构图
SMILES: CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)OC(CO)CO
化学属性
| Mol. Formula | C23H38O4 |
|---|---|
| Mol. Weight | 378.55 |
别名和识别编码
| Chemical Name | Glycerol (90%) |
|---|---|
| CAS Number | 53847-30-6 |
| Synonym | (5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraenoic Acid 2-Hydroxy-1-(hydroxymethyl)ethyl Ester (all-Z)-5,8,11,14-Eicosatetraenoic Acid 2-Hydroxy-1-(hydroxymethyl)ethyl Ester (all-Z)-5,8,11,14-Eicosatetraenoic acid 2-hydroxy-1-(hydroxymethyl)ethyl ester (all-Z)-5,8,11,14-Eicosatetraenoic acid 2-hydroxy-1-(hydroxymethyl)ethyl ester 2-Arachidonoylglycerol 2-Monoarachidonoylglycerol 2-AG 2-AG 2-Arachidonoylglycerol 2-Arachidonyl glycerol 2-Monoarachidonoylglycerol |
| PubChem Substance ID | 24891388 |
| EC Number | 200-835-2 |
| MDL Number | MFCD01862600 |
| Chemical Name Translation | 2-Arachidonyl |
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分类
- Glycerols
- Fatty Acid Derivatives & Lipids
- Pharmaceuticals
- Intermediates & Fine Chemicals
- {SNA} AN-AZ, Bioactive Small Molecules, Cannabinoids, Cell Biology, Cell Signaling and Neuroscience, Neurobiology, Neuroscience, Pharmacologicals
- {SNA} AN-AZ, Bioactive Small Molecule Alphabetical Index, Cannabinoids, Neurobiology,
产品应用
- 2-Arachidonoylglycerol is a major endocannabinoid, which can inhibit synaptic transmission by presynaptic cannabinoid CB1 receptors. It plays an inhibitory role in the bombesin-induced activation of c
相关文献及参考
- Jensen, R., et al.: Pharmacol. Rev., 60, 1 (2008),
- Lu, L., et al.: Eur. J. Pharmacol., 590, 177 (2008),
- Yokotani, K., et al.: Eur. J. Pharmacol., 512, 29 (2005),
- [1]. Stella N, et al. A second endogenous cannabinoid that modulates long-term potentiation. Nature. 1997 Aug 21;388(6644):773-8.
安全信息
GHS Symbol
- H332 Harmful if inhaled 吸入有害
- H319 Causes serious eye irritation 严重刺激眼睛
- H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
- H302 Harmful if swallowed 吞食有害
- H302+H332
- P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
- P305+P351+P338
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P370+P378
- P403+P235
- R11 Highly flammable 非常易燃
- R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
- R36 Irritating to eyes 刺激眼睛
- S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
- S16 Keep away from sources of ignition - No smoking 远离火源，禁止吸烟；
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