Sodium (S)-2-Amino-3-(4-(4-Hydroxy-3-Iodophenoxy)-3,5-DIIodophenyl)Propanoate (S)-2-氨基-3-(4-(4-羟基-3-碘苯氧基)-3,5-二碘苯基)丙酸钠

CAS 55-06-1 MFCD00002594

化学结构图

55-06-1
SMILES: [Na+].N[C@@H](CC1=CC(I)=C(OC2C=C(I)C(O)=CC=2)C(I)=C1)C([O-])=O |&1:2|

化学属性

Mol. FormulaC15H11I3NNaO4
Mol. Weight673
Melting Point196-196
TSCANo
Density1.422
SolubilityDMSO 100 mg/mL Water <1 mg/mL Ethanol <1 mg/mL
Appearance powder

别名和识别编码

Chemical NameSodium (S)-2-Amino-3-(4-(4-Hydroxy-3-Iodophenoxy)-3,5-DIIodophenyl)Propanoate
Synonym 3,3′,5-三碘-L-甲状腺原氨酸 钠盐 H-THY(3,3',5-I3)-ONA Liothyronine Sodium USP28 Liothyronine, O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine sodium salt O-[4-HYDROXY-3-IODOPHENYL]-3,5-DIIODO-L-TYROSINE SODIUM SALT
MDL NumberMFCD00002594
PubChem Substance ID24900071
Beilstein Registry Number8179867
CAS Number55-06-1
EC Number200-223-5
Chemical Name Translation(S)-2-氨基-3-(4-(4-羟基-3-碘苯氧基)-3,5-二碘苯基)丙酸钠
Merck Number5510
InChIKeySBXXSUDPJJJJLC-YDALLXLXSA-M
LabNetwork Molecule IDLN01310778
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分类

  • {SA} Bioactive Small Molecules, Cell Biology, Cell Culture, Cell Signaling and Neuroscience, Cytokines, Growth Factors and Hormones, Hormones, Other Protein/Peptide Hormones, Peptides and Proteins, Peptides for Cell Biology, Reagents and Supplements, T,
  • {SNA} Bioactive Small
  • {SNA} Bioactive Small Molecules, Cell Biology, Cell Culture, Cell Signaling and Neuroscience, Cytokines, Growth Factors and Hormones, Hormones, Other Protein/Peptide Hormones, Peptides and Proteins, Peptides for Cell Biology, Reagents and Supplements, T, Thyroid Hormones, Triiodo-L-Thyronine (T3)
  • {SNA} Bioactive Small Molecul

相关文献及参考

  • Watt, F., and Molloy, P., Enhancer trap method using a green fluorescent protein reporter plasmid for cloning tissue-specific enhancers active in prostate cells. Meth. Mol. Med. 81 , 321-31, (2003) 摘要
  • Darbro, B.W., et al., Co-regulation of p16INK4A and migratory genes in culture conditions that lead to premature senescence in human keratinocytes. J. Invest. Dermatol. 125 , 499-509, (2005) 摘要
  • Sørensen, C.M., et al., Hormonal regulation of mannan-binding lectin synthesis in hepatocytes. Clin. Exp. Immunol. 145 , 173-82, (2006) 摘要
  • Gangatirkar, P., et al., Establishment of 3D organotypic cultures using human neonatal epidermal cells. Nat. Protoc. 2 , 178-86, (2007) 摘要
  • Antolino-Lobo, I., et al., Differential roles of phase I and phase II enzymes in 3,4-methylendioxymethamphetamine-induced cytotoxicity. Drug Metab. Dispos. 38 , 1105-12, (2010) 摘要
  • Sonoda, S., et al., A Protocol For The Culture And Differentiation Of Highly Polarized Human Retinal Pigment Epithelial Cells. Nat. Protoc. 4 , 662-73, (2009) 摘要
  • Nardone, A., et al., Long-term Cultures Of Stem/progenitor Cells From Lobular And Ductal Breast Carcinomas Under Non-adherent Conditions. Cytotechnology 63 , 67-80, (2011) 摘要
  • Nishi, H., et al., MicroRNA-27a Regulates Beta Cardiac Myosin Heavy Chain Gene Expression By Targeting Thyroid Hormone Receptor β1 In Neonatal Rat Ventricular Myocytes Mol. Cell. Biol. 31 , 744-755, (2011) 摘要
  • Merck 14 ,5510

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
RTECSYP2836500
Safety Statements
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
Signal word Warning
GHS Symbol
Precautionary statements
  • P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛，皮肤或衣服。
Storage condition Light Sensitive 储存温度-20°C 2-8°C

其他信息

  • MSDS 信息:Sodium (2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoate(55-06-1).msds
  • Sigma Aldrich:55-06-1(sigmaaldrich)
  • 三碘代甲状腺素钠盐价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 T0454 3,3',5-三碘-L-甲腺原氨酸钠盐 3,3',5-Triiodo-L-thyronine Sodium Salt 100MG 323元 2010/06/21 139860100 三碘代甲状腺素钠盐 3,3',5-Triiodo-L-thyronine, sodium salt 95% 10 GR 10817元 2010/06/21 139860010 三碘代甲状腺素钠盐 3,3',5-Triiodo-L-thyronine, sodium salt 95% 1 GR 2423元
  • 图谱信息:三碘代甲状腺素钠盐(55-06-1)核磁图( 13 CNMR) 三碘代甲状腺素钠盐(55-06-1)核磁图( 1 HNMR) 三碘代甲状腺素钠盐(55-06-1)红外图谱(IR1)
  • 比旋光度:20 ° (c=2,alcohol/1.2N HCl)
  • TCI Shanghai:3,3',5-三碘-L-甲腺原氨酸钠 3,3',5-Triiodo-L-thyronine Sodium Salt,>;98.0%(LC)(T)(55-06-1)
  • Acros Organics:3,3',5-三碘代-L-甲腺原氨酸钠盐 3,3',5-Triiodo-L-thyronine, sodium salt, 95%(55-06-1)
  • F:3-8-10
  • MOL 文件:55-06-1.mol

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Cytokines, Growth Factors and Hormones - Cell Signaling and Neuroscience
  5. Hormones - Cytokines, Growth Factors and Hormones
  6. Other Protein/Peptide Hormones - Hormones
  7. Triiodo-L-Thyronine (T3) - Other Protein/Peptide Hormones
  1. Thyroid Hormones - Peptides for Cell Biology
  2. Triiodo-L-Thyronine (T3) - Thyroid Hormones
  1. Functional Group 官能团索引
  2. carboxylic acid salt
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Cell Signaling and Neuroscience
  4. Peptides and Proteins
  5. Thyroid Hormones
  6. Thyroxine
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Peptides
  4. Peptides for Cell Biology
  5. Thyroid Hormones
  6. Thyroxine
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Cell Signaling and Neuroscience
  4. Cytokines, Growth Factors and Hormones
  5. Hormones
  6. Other Protein/Peptide Hormones
  7. Thyroxine (T4)
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Cell Signaling and Neuroscience
  4. Peptides and Proteins
  5. Peptides for Cell Biology
  6. Thyroid Hormones
  7. Thyroxine

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