Hexamethonium Bromide 溴化六甲双铵

CAS 55-97-0 MFCD00011787

化学结构图

55-97-0
SMILES: C[N+](C)(C)CCCCCC[N+](C)(C)C.[Br-].[Br-]

化学属性

Mol. FormulaC12H30Br2N2
Mol. Weight362.19
Density1.422
Melting Point-285 °C
TSCAYes

别名和识别编码

Chemical NameHexamethonium bromide
Synonym Hexamethonium (Bromide) Hexamethonium Bitartrate Hexamethonium Bromide Hexamethonium Chloride Hexamethonium Dibromide Hexamethonium Dibromide Dihydrate Hexamethonium Dichloride Dihydrate Hexamethonium Dihydroxide Hexamethonium Diiodide Hexamethonium Dimethylsulfate Hexamethonium Diperchlorate Hexamethonium Iodid {} {LY} Hexamethonium (Bromide) {} {} {LY} Hexamethonium (Bromide) {} {} {} {LY} Hexamethonium (Bromide) {} {} {} {} {LY} Hexamethonium (Bromide) {} {} {} {} {} {LY} Hexamethonium (Bromide) {} {} {} {} {} {} {} {} {} {} {} {} {LY} Hexamethonium (Bromide) {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Hexamethonium (Bromide) {} {} {} {} {} {} {} {} {LY} Hexamethonium (Bromide) {} {} {} {} {} {} {} {} {} {LY} Hexamethonium (Bromide) {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Hexamethonium (Bromide) {} {} {} {} {} {} {} {
MDL NumberMFCD00011787
CAS Number55-97-0
EC Number200-249-7
Beilstein Registry Number3715749
PubChem Substance ID5938
Merck Number4688
Reaxys-RN3715749
Chemical Name Translation溴化六甲双铵
Wiswesser Line Notation1K1&1&6K1&1&1 &E 2
LabNetwork Molecule IDLN01347834
Canonical SMILESC[N+](C)(C)CCCCCC[N+](C)(C)C.[Br-].[Br-]
InChIInChI=1S/C12H30N2.2BrH/c1-13(2,3)11-9-7-8-10-12-14(4,5)6;;/h7-12H2,1-6H3;2*1H/q+2;;/p-2
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分类

  • {SNA} Antagonists, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Cholinergics, H, Ion Channels, Ligand-Gated Ion Channels, Neuroscience, Neurotransmission, Neurotransmitters, Nicotinic Acetylcholine Receptor Modulators
  • {SNA} Antagonists,
  • {SA} Ammonium Salts, Bioactive Small Molecules, Cell Biology, Chemical Synthesis, H, Phase Transfer Catalysts, Synthetic Reagents
  • {SNA} Antagonists, Cholinergics, H, Ion Channels, Ligand-Gated Ion Channels, Neuroscience, Neurotransmission,

安全信息

Signal word Warning
GHS Symbol
WGK Germany2
Safety Statements
  • S22 Do not breathe dust 不要吸入粉尘;
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Precautionary statements
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P305+P351+P338
  • P307+P311
  • P308+P311
  • P308+P316
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
RTECSBQ8575000
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Hazard statements
  • H303 May be harmfully swallowed 吞食可能有害
  • H370 Causes damage to organs 导致器官损伤
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 50300 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   SKNEA7 Shionogi Kenkyusho Nenpo.  Annual Report of Shionogi Research
   Laboratory.  (Shionogi Seiyaku K.K. Kenkyusho, 5-12-4 Sagisu, Fukushima-ku,
   Osaka 553, Japan)  No.1-    1951-  Volume(issue)/page/year: 10,15,1960

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 838 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,356,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2891 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   SKNEA7 Shionogi Kenkyusho Nenpo.  Annual Report of Shionogi Research
   Laboratory.  (Shionogi Seiyaku K.K. Kenkyusho, 5-12-4 Sagisu, Fukushima-ku,
   Osaka 553, Japan)  No.1-    1951-  Volume(issue)/page/year: 10,15,1960

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 22 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BCPCA6 Biochemical Pharmacology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.1-    1958-  Volume(issue)/page/year:
   2,233,1959

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE O

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Human - woman
DOSE                    : 46 mg/kg
SEX/DURATION            : female 31-34 week(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - gastrointestinal
   system
   Reproductive - Effects on Newborn - other neonatal measures or effects
REFERENCE :
   ADCHAK Archives of Disease in Childhood.  (British Medical Journal, POB
   560B, Kennebunkport, ME 04046)  V.1-    1926-  Volume(issue)/page/year:
   29,354,1954

Storage condition 2-8°C, sealed storage, away from moisture {LY} 2-8°C, sealed storage, away from moisture {} {LY} 2-8°C, sealed storage, away from moisture {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, sealed storage, away from moisture {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, seal

其他信息

  • Sigma Aldrich:55-97-0(sigmaaldrich)
  • 上游原料:乙醇 --> 乙酸乙酯 --> 氢溴酸 --> 氢氧化钙 --> 三甲胺 --> 1,6-己二醇 --> 三甲胺盐酸盐 --> 1,6-二溴己烷
  • Acros Organics:Hexamethonium bromide hydrate, 98+%(55-97-0)
  • 溴化六甲铵价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 H0481 溴化六甲铵 Hexamethonium Bromide 500G 5310元 2014/06/02 H0481 溴化六甲铵 Hexamethonium Bromide 25G 568元 2010/06/21 204705000 溴化六甲铵 Hexamethonium bromide hydrate 98+% 500 GR 8363元
  • MOL 文件:55-97-0.mol
  • 检测方法:Silver Method
  • 图谱信息:溴化六甲铵(55-97-0)红外图谱(IR1) 溴化六甲铵(55-97-0)质谱(MS) 溴化六甲铵(55-97-0)红外图谱(IR2)
  • TCI Shanghai:溴化六甲铵 Hexamethonium Bromide,>;98.0%(T)(55-97-0)

系列性分类


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