6-Maleimidohexanoic acid 6-(2,5-二氧代-2,5-二氢-1H-吡咯-1-基)己酸

CAS 55750-53-3 MFCD00043140

化学结构图

55750-53-3
SMILES: O=C(O)CCCCCN1C(=O)C=CC1=O

化学属性

Mol. FormulaC10H13NO4
Mol. Weight211
Melting Point86.0 to 91.0 deg-C
TSCANo

别名和识别编码

Chemical Name6-Maleimidohexanoic acid
CAS Number55750-53-3
Alfabeta NameMALEIMIDOHEXANOICACID 6-
MDL NumberMFCD00043140
Synonym ?-Male Maleimidocaproic acid 6-Maleimidocaproic acid 6-Maleimide hexanoic acid 6-Maleimidocaproic acid, N-Maleoyl-6-aminocaproic acid, N-(5-Carboxypentyl)maleimide 2,5-Dihydro-2,5-dioxo-1H-pyrrole-1-hexanoic acid 6-Maleimide hexanoic acid 6-Maleimidocaproic acid N-Maleoyl-6-aminocaproic acid MCA Maleimidocaproic acid N-(5-Carboxypentyl)maleimide 6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoic Acid N-(5-Carboxy-n-pentyl)maleimide N-(5-Carboxypentyl)maleimide 2,5-Dihydro-2,5-dioxo-1H-pyrrole-1-hexanoic acid 6-Maleimidohexanoic Acid
Beilstein Registry Number1532405
PubChem Substance ID160871405
Chemical Name Translation6-(2,5-二氧代-2,5-二氢-1H-吡咯-1-基)己酸
Reaxys-RN1532405
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分类

  • {SNA} Asymmetric Synthesis, Carboxylic Acids, Chemical Synthesis, Chiral Building Blocks, Organic Building Blocks
  • MTS & Sulfhydryl Active Reagents
  • {SNA} Curing Agents for Epoxides, Polymer Additives, Polymer Science, 材料科学
  • {SA} Crosslinking Agents and Additives for Epoxides, Materials Science, Polymer Additives, Polymer Science
  • Cross Linking Reagents
  • Maleimide Derivatives

产品应用

  • A sulfhydryl reactive heterobifunctional crosslinking reagent. Widely used probe for introducing maleimides groups into biomolecules. A probe for thiol groups in proteins.

相关文献及参考

  • Griffith, D.G., et al.: FEBS Lett., 134, 261 (1981)
  • D.G. Griffith FEBS Lett. 134 , 261, (1981) 摘要
  • O. Keller, J. Rudinger Helv. Chim. Acta 58 , 531, (1975) 摘要
  • Beil. 21 ,V,10,30

安全信息

Warnings IRRITANT
Safety Statements
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置；
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S37 Wear suitable gloves 戴适当手套；
Risk Statements
Storage condition 0-10°C Moisture Sensitive
GHS Symbol
WGK Germany3
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P352+P332+P313+P362+P364
  • P305+P351+P338
  • P305+P351+P338+P337+P313
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H318 Causes serious eye damage 严重伤害眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Signal word
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes Xi

系列性分类

  1. Chemical Synthesis 化学合成
  2. Asymmetric Synthesis 不对称合成
  3. Chiral Building Blocks 手性分子砌块
  4. Organic Building Blocks - Chiral Building Blocks
  5. Carboxylic Acids - Organic Building Blocks
  1. Materials Science 材料科学
  2. Products for Polymer Science Research
  3. Polymer Additives - Polymer Science
  4. Crosslinking Agents and Additives for Epoxides - Polymer Additives

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