(S)-2-Amino-5-(((R)-1-((Carboxymethyl)Amino)-3-(Nitrosothio)-1-Oxopropan-2-Yl)Amino)-5-Oxopentanoic Acid (S)-2-氨基-5-(((R)-1-((羧甲基)氨基)-3-(亚硝基硫基)-1-氧代丙-2-基)氨基)-5-氧代戊酸

CAS 57564-91-7 MFCD00214341

化学结构图

57564-91-7
SMILES: N[C@@H](CCC(=O)N[C@@H](CSN=O)C(=O)NCC(O)=O)C(O)=O

化学属性

Mol. FormulaC10H16N4O7S
Mol. Weight336.32

别名和识别编码

Chemical Name(S)-2-Amino-5-(((R)-1-((Carboxymethyl)Amino)-3-(Nitrosothio)-1-Oxopropan-2-Yl)Amino)-5-Oxopentanoic Acid
CAS Number57564-91-7
Synonym Nitrosoglutathione RVC 588 L-?-Glutamyl-S-nitroso-L-cysteinyl-glycine GNSO S-Nitrosoglutathione GSNO SNOG SNOG
MDL NumberMFCD00214341
PubChem Substance ID24278587
Beilstein Registry Number3566211
Chemical Name Translation(S)-2-氨基-5-(((R)-1-((羧甲基)氨基)-3-(亚硝基硫基)-1-氧代丙-2-基)氨基)-5-氧代戊酸
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分类

  • Nitric Oxide Reagents
  • {SNA} Application Index, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling Enzymes, Cell Signaling and Neuroscience, Enzyme Substrates, Enzymes, Inhibitors, and Substrates, N, NO Donors, Nitric Oxide Donors, Nitric Oxide Metabolism, Nitric Oxide Synthase/NO Donor, Nitric Oxide and Cell Stress, Substrates by Enzyme
  • Peptides
  • {SNA} Application Index, Cell Signaling Enzymes, Enzyme Substrates, NO Donors, Nitric Oxide Donors, Nitric Oxide Metabolism, Nitric Oxide Synthase/NO Donor, Substrates by Enzyme, 一氧化氮代谢,

产品应用

  • A carrier of nitric oxide, relaxing smooth muscle and inhibiting platelet activation.

相关文献及参考

  • Thompson, C., et al.: Toxicol., App. Pharmacol., 233, 355 (2008),

安全信息

WGK Germany3
GHS Symbol
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
RTECSMC0558000
Signal word Warning
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes Xi
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36 Wear suitable protective clothing 穿戴适当的防护服；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 5 umol/plate
REFERENCE :
   BCPCA6 Biochemical Pharmacology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.1-    1958-  Volume(issue)/page/year:
   35,3847,1986

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Bioactive Small Molecules - Cell Biology
  4. N - Bioactive Small Molecules
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Application Index - Enzymes, Inhibitors, and Substrates
  5. Cell Signaling Enzymes - Application Index
  6. Nitric Oxide Metabolism - Cell Signaling Enzymes
  7. NO Donors - Nitric Oxide Metabolism

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