1-(3-Chlorophenyl)-3-(1-Methyl-4-Oxo-4,5-Dihydro-1H-Imidazol-2-Yl)Urea 1-(3-氯苯基)-3-(1-甲基-4-氧代-4,5-二氢-1H-咪唑-2-基)脲

CAS 57653-26-6 MFCD00868019

化学结构图

57653-26-6
SMILES: CN1CC(=O)N=C1NC(=O)NC1C=C(Cl)C=CC=1

化学属性

Mol. FormulaC11H11ClN4O2
Mol. Weight266.68

别名和识别编码

Chemical Name1-(3-Chlorophenyl)-3-(1-Methyl-4-Oxo-4,5-Dihydro-1H-Imidazol-2-Yl)Urea
Synonym N-(3-Chlorophenyl)-N′-(4,5-dihydro-1-methyl-4-oxo-1H-imidazole-2-yl)urea Fenobam N-(3-Chlorophenyl)-N'-(4,5-dihydro-1-methyl-4-oxo-1H-imidazole-2-yl)urea
MDL NumberMFCD00868019
PubChem Substance ID24894721
Chemical Name Translation1-(3-氯苯基)-3-(1-甲基-4-氧代-4,5-二氢-1H-咪唑-2-基)脲
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • {SNA} Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Excitatory Amino Acids, F, Johnson & Johnson, Neuroscience, Neurotransmission, Neurotransmitters, Others
  • {SNA} Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Excitatory Amino Acids, F, Johnson & Johnson, Neuroscience, Neurotransmission, Neurotransmitters, Other Excitatory Amino Acids, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学

相关文献及参考

  • [2]. Laura F, et al. The Metabotropic Glutamate Receptor 5 Negative Allosteric Modulator Fenobam: Pharmacokinetics, Side Effects, and Analgesic Effects in Healthy Human Subjects.bioRxiv 391383;
  • [3]. Keck TM, et al. Fenobam sulfate inhibits cocaine-taking and cocaine-seeking behavior in rats: implications for addiction treatment in humans. Psychopharmacology (Berl). 2013;229(2):253-265.
  • [1]. Porter RH, et al. Fenobam: a clinically validated nonbenzodiazepine anxiolytic is a potent, selective, and noncompetitive mGlu5 receptor antagonist with inverse agonist activity. J Pharmacol Exp Ther. 2005 Nov;315(2):711-21.
  • [1]. Porter RH, et al. Fenobam: a clinically validated nonbenzodiazepine anxiolytic is a potent, selective, and noncompetitive mGlu5 receptor antagonist with inverse agonist activity. J Pharmacol Exp Ther. 2005 Nov;315(2):711-21.
  • [2]. Laura F, et al. The Metabotropic Glutamate Receptor 5 Negative Allosteric Modulator Fenobam: Pharmacoki

安全信息

GHS Symbol
Precautionary statements
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P301+P310
Hazard statements
  • H300 Fatal if swallowed 吞食致命
WGK Germany3
Signal word Danger
Personal Protective Equipment Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Safety Statements
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
Hazard Codes T
Risk Statements
  • R25 Toxic if swallowed 吞咽有毒

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Approved Therapeutics/Drug Candidates - Cell Signaling and Neuroscience
  5. Johnson & Johnson - Approved Therapeutics/Drug Candidates
  1. Medical Research Areas
  2. GPCR & G Protein
  3. mGluR  (代谢型谷氨酸受体)

相关产品推荐