Calcium Ionophore A23187 hemicalcium salt 钙离子载体 A23187 半钙盐

CAS 59450-89-4 MFCD00077678

化学结构图

59450-89-4
SMILES: C[C@@H]1CC[C@]2(O[C@@H]1CC1=NC3C(=C(C=CC=3O1)NC)C(=O)O[Ca]OC(=O)C1C3N=C(C[C@H]4O[C@@]5(CC[C@H]4C)O[C@H]([C@H](C)C(=O)C4=CC=CN4)[C@H](C)C[C@H]5C)OC=3C=CC=1NC)O[C@H]([C@H](C)C(=O)C1=CC=CN1)[C@H](C)C[C@H]2C

化学属性

Mol. FormulaC29H36Ca0.5N3O6
Mol. Weight542.65

别名和识别编码

Chemical NameCalcium Ionophore A23187 hemicalcium salt
Synonym Calcimycin hemicalcium salt A23187 hemicalcium salt Antibiotic A 23187 Calcium Ionophore A23187 hemicalcium salt Calimycin A23187 半钙盐 Antibiotic A 23187 Calcimycin hemicalcium salt Calimycin 钙离子载体 A23187 半钙盐
CAS Number59450-89-4
PubChem Substance ID24893145
Beilstein Registry Number6765084
MDL NumberMFCD00077678
Chemical Name Translation钙离子载体 A23187 半钙盐
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分类

  • A - K, Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics A-F, Bioactive Small Molecules, C-CH, Calcium Ionophores, Calcium Signaling Research Tools, Cell Biology, Cell Signaling and Neuroscience, Interferes with Cell Membrane Permeability (Ionophores), Intracellular Calcium Signaling, Mechanism of Action, Spectrum of Activity
  • {SNA} A - K, Antibacterial, Antibiotics A to Z, Antibiotics A-F, Calcium Ionophores, Calcium Signaling Research Tools, Interferes with Cell Membrane Permeability (Ionophores), Intracellular Calcium Signaling, Mechanism of Action,

相关文献及参考

  • Knowles, R.G., and Moncada, S., Nitric oxide as a signal in blood vessels. Trends Biochem. Sci. 17 , 399-402, (1992)
  • Markram, H., and Segal, M., Calcimycin potentiates responses of rat hippocampal neurons to N-methyl-D-aspartate. Brain Res. 540 , 322-324, (1991) 摘要

安全信息

GHS Symbol
WGK Germany3
Hazard Codes Xi
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
Signal word Warning
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

系列性分类

  1. Life Science 生命科学
  2. Antibiotics 抗生素
  3. Antibiotics A to Z - Antibiotics
  4. Antibiotics A-F - Antibiotics A to Z
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Intracellular Calcium Signaling - Cell Signaling and Neuroscience
  5. Calcium Signaling Research Tools - Intracellular Calcium Signaling
  6. Calcium Ionophores - Calcium Signaling Research Tools

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