beta-D-Allofuranuronic acid,5-((2-amino-4-hydroxy-4-(5-hydroxy-2-pyridinyl)-3-methyl-1-oxobutyl)amino)-1,5-dideoxy-1-(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-, (2S-(2R*,3R*,4R*))-

CAS 59456-70-1 MFCD00869648

化学结构图

59456-70-1
SMILES: C[C@@H]([C@H](N)C(=O)N[C@H]([C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=CC(=O)NC1=O)C(O)=O)[C@H](O)C1C=CC(O)=CN=1

化学属性

Mol. FormulaC20H25N5O10
Mol. Weight495.44

别名和识别编码

Chemical NameNikkomycin Z from Streptomyces tendae
MDL NumberMFCD00869648
PubChem Substance ID24897849
Beilstein Registry Number0873216
Synonym Nikkomycin Z Neopolyoxin C Nikkomycin Z from Streptomyces tendae
CAS Number59456-70-1
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分类

  • {SA} Antibiotics, Antibiotics A to Z, Antibiotics N-S, Antifungal, Chemical Structure Class, Inhibits an Enzyme, Interferes with Cell Wall Synthesis, Mechanism of Action, Peptidyl Nucleosides, Spectrum of Activity
  • {SNA} Antibiotics, Antibiotics A to Z, Antibiotics N-S, Antifungal, Chemical Structure Class, Glycobiology, Inhibitors, Inhibitors and Substrates, Inhibits an Enzyme, Interferes with Cell Wall Synthesis, Mechanism of Action, Peptidyl Nucleosides, Post-Translational Modification, Proteomics, Spectrum of Activity
  • {SNA} Antibiotics

安全信息

WGK Germany3
GHS Symbol
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
RTECSBA2928200
Signal word Warning
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes Xi
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36 Wear suitable protective clothing 穿戴适当的防护服；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >250 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ABCHA6 Agricultural and Biological Chemistry.  (Maruzen Co. Ltd., POB 5050,
   Tokyo International, Tokyo 100-31, Japan)  V.25-    1961-
   Volume(issue)/page/year: 44,1709,1980

系列性分类

  1. Life Science 生命科学
  2. Antibiotics 抗生素
  3. Antibiotics A to Z - Antibiotics
  4. Antibiotics N-S - Antibiotics A to Z
  1. Life Science 生命科学
  2. Antibiotics 抗生素
  3. Antibiotics A to Z - Antibiotics
  4. Antibiotics N-S - Antibiotics A to Z
  1. Life Science 生命科学
  2. Antibiotics 抗生素
  3. Chemical Structure Class - Antibiotics
  4. Peptidyl Nucleosides - Chemical Structure Class

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