1'-Hydroxymidazolam α-羟基咪达唑仑溶液，100ppm,1ml/支
CAS 59468-90-5 MFCD00871458
化学结构图
SMILES: OCC1=NC=C2CN=C(C3C=C(Cl)C=CC=3N12)C1=CC=CC=C1F
化学属性
| Mol. Formula | C18H13ClFN3O |
|---|---|
| Mol. Weight | 342 |
别名和识别编码
| Chemical Name | 1’-Hydroxy Midazolam |
|---|---|
| CAS Number | 59468-90-5 |
| Synonym | 8-Chloro-6-(2-fluorophenyl)-4H-imidazo[1,5-a][1,4]benzodiazepine-1-methanol 1'-Hydroxymidazolam |
| MDL Number | MFCD00871458 |
| PubChem Substance ID | 24724655 |
| Chemical Name Translation | α-羟基咪达唑仑溶液，100ppm,1ml/支 |
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分类
- Aromatics
- Heterocycles
- Metabolites & Impurities
- Pharmaceuticals
- Intermediates & Fine Chemicals,
- {SNA} Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Drug and Xenobiotic Metabolism, H, Multi-Drug Resistance and Drug Metabolism, Substrates, Inducers, Inhibitors
产品应用
- A metabolite of Midazolam (M343000).
相关文献及参考
- [2]. Balk M, et, al. Differential depression of neuronal network activity by midazolam and its main metabolite 1-hydroxymidazolam in cultured neocortical slices. Sci Rep. 2017 Jun 14; 7(1): 3503.
- Dundee, J., et al.: Drugs, 28, 519
- [1]. Hasegawa T, et, al. Increase in the systemic exposure of primary metabolites of Midazolam in rat arising from CYP inhibition or hepatic dysfunction. Drug Metab Pharmacokinet. 2017 Feb; 32(1): 69-76.
- [1]. Hasegawa T, et, al. Increase in the systemic exposure of primary metabolites of Midazolam in rat arising from CYP inhibition or hepatic dysfunction. Drug Metab Pharmacokinet. 2017 Feb; 32(1): 69-76.
- [2]. Balk M, et, al. Differential depression of neuronal network activity by midazolam and its main metabolite 1-hydroxymidazolam in cultured neocortical slices. Sci Rep. 2017 Jun 14; 7(1): 3503.
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