Diethazine N,N-二乙基-2-(10H-吩噻嗪-10-基)乙烷-1-胺

CAS 60-91-3 MFCD00242900

化学结构图

60-91-3
SMILES: CCN(CC)CCN1c2ccccc2Sc2ccccc21

化学属性

Mol. FormulaC18H22N2S
Mol. Weight298.45
Boiling Point167-175 °C at 760 mmHg

别名和识别编码

Chemical NameDiethazine
Synonym N,N-diethyl-2-(10H-phenothiazin-10-yl)ethan-1-amine {LY} N,N-diethyl-2-(10H-phenothiazin-10-yl)ethan-1-amine diethazine diethazine monohydrochloride diethazine radical ion (1+) {} {LY} N,N-diethyl-2-(10H-phenothiazin-10-yl)ethan-1-amine {} {} {LY} N,N-diethyl-2-(10H-phenothiazin-10-yl)ethan-1-amine {} {} {} {LY} N,N-diethyl-2-(10H-phenothiazin-10-yl)ethan-1-amine {} {} {} {} {LY} N,N-diethyl-2-(10H-phenothiazin-10-yl)ethan-1-amine {} {} {} {} {} {LY} N,N-diethyl-2-(10H-phenothiazin-10-yl)ethan-1-amine {} {} {} {} {} {} {LY} N,N-diethyl-2-(10H-phenothiazin-10-yl)ethan-1-amine {} {} {} {} {} {} {} {LY} N,N-diethyl-2-(10H-phenothiazin-10-yl)ethan-1-amine {} {} {} {} {} {} {} {} {LY} N,N-diethyl-2-(10H-phenothiazin-10-yl)ethan-1-amine {} {} {} {} {} {} {} {} {} {LY} N,N-diethyl-2-(10H-phenothiazin-10-yl)ethan-1-amine {} {} {} {} {} {} {} {} {} {} {LY} N,N-diethyl-2-(10H-phenothiazin-10-yl)ethan-1-amine {} {} {} {} {} {} {} {} {} {} {} {LY
Wiswesser Line NotationT C666 BN ISJ B2N2&2
CAS Number60-91-3
PubChem Substance ID65535
InChIInChI=1S/C18H22N2S/c1-3-19(4-2)13-14-20-15-9-5-7-11-17(15)21-18-12-8-6-10-16(18)20/h5-12H,3-4,13-14H2,1-2H3
Chemical Name TranslationN,N-二乙基-2-(10H-吩噻嗪-10-基)乙烷-1-胺
Canonical SMILESCCN(CC)CCN1C2=CC=CC=C2SC3=CC=CC=C31
MDL NumberMFCD00242900
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安全信息

RTECSSO4200000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 56 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   HPPAAL Helvetica Physiologia et Pharmacologica Acta.  (Basel, Switzerland)
   V.1-26, 1943-68. Discontinued.  Volume(issue)/page/year: 16,277,1958

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 450 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - rigidity (including catalepsy)
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 134,255,1961

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 450 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PSCBAY Psychopharmacology Service Center, Bulletin.  (Bethesda, MD)  V.1-3,
   1961-65.  For publisher information, see PSYBB9.  Volume(issue)/page/year:
   2,17,1963

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 28500 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 103,371,1955

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE

Storage condition

系列性分类

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