N-methylpyridine-2-carboxamide N-甲基-2-吡啶甲酰胺(索拉菲尼杂质)

CAS 6144-78-1 MFCD10686721

化学结构图

6144-78-1
SMILES: CNC(=O)c1ccccn1

化学属性

Mol. FormulaC7H8N2O
Mol. Weight136.15
Boiling Point128 °C at 12 mmHg

别名和识别编码

Chemical NameN-Methylpicolinamide
CAS Number6144-78-1
Synonym N-Methylpicolinamide (Sorafenib Impurity) {LY} N-Methylpicolinamide (Sorafenib Impurity) N-methylpicolinamide {} {LY} N-Methylpicolinamide (Sorafenib Impurity) {} {} {LY} N-Methylpicolinamide (Sorafenib Impurity) {} {} {} {LY} N-Methylpicolinamide (Sorafenib Impurity) {} {} {} {} {LY} N-Methylpicolinamide (Sorafenib Impurity) {} {} {} {} {} {LY} N-Methylpicolinamide (Sorafenib Impurity) {} {} {} {} {} {} {LY} N-Methylpicolinamide (Sorafenib Impurity) {} {} {} {} {} {} {} {LY} N-Methylpicolinamide (Sorafenib Impurity) {} {} {} {} {} {} {} {} {LY} N-Methylpicolinamide (Sorafenib Impurity) {} {} {} {} {} {} {} {} {} {LY} N-Methylpicolinamide (Sorafenib Impurity) {} {} {} {} {} {} {} {} {} {} {LY} N-Methylpicolinamide (Sorafenib Impurity) {} {} {} {} {} {} {} {} {} {} {} {LY} N-Methylpicolinamide (Sorafenib Impurity) {} {} {} {} {} {} {} {} {} {} {} {} {LY} N-Methylpicolinamide (Sorafenib Impurity) {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} N-Methylpicolina
Chemical Name TranslationN-甲基-2-吡啶甲酰胺(索拉菲尼杂质)
PubChem Substance ID12272691
InChIInChI=1S/C7H8N2O/c1-8-7(10)6-4-2-3-5-9-6/h2-5H,1H3,(H,8,10)
MDL NumberMFCD10686721
Canonical SMILESO=C(C1=NC=CC=C1)NC
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分类

  • Amines
  • Aromatics
  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

  • N-Substituted picolinamides as drowsiness-free central muscle relaxants.

相关文献及参考

  • Takahashi, H., et al.: Bioorg. Med. Chem. Lett.,?19,?5436 (2009),

安全信息

Storage condition Store at room temperature {LY} Store at room temperature {} {LY} Store at room temperature {} {} {LY} Store at room temperature {} {} {} {LY} Store at room temperature {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
Hazard statements
  • H302 Harmful if swallowed 吞食有害
  • H312 Harmful in contact with skin 皮肤接触有害
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H332 Harmful if inhaled 吸入有害
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P264+P265
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P317
  • P302+P352
  • P304+P340
  • P305+P351+P338
  • P317
  • P319
  • P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
  • P330 Rinse mouth. 漱口
  • P332+P317
  • P337+P317
  • P362+P364
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....

系列性分类

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