7?-Chloro-16?-methyl Prednisolone

CAS 67452-97-5 MFCD05662214

化学结构图

67452-97-5
SMILES: C[C@@H]1C[C@H]2[C@H]3[C@H]([C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO)[C@@]1(C)C=CC(=O)C=C1C[C@H]3Cl

化学属性

Mol. FormulaC22H29ClO5
Mol. Weight408.92

别名和识别编码

Chemical Name7?-Chloro-16?-methyl Prednisolone
CAS Number67452-97-5
Synonym (7?,11?,16?)-7-Chloro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione 7?-Chloro-16?-methylprednisolone Alclometasone Alclomethasone
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分类

  • Metabolites & Impurities
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • Steroids

产品应用

  • A metabolite of Alclometasone dipropionate; a synthetic glucocorticoid steroid for topical use in dermatology as anti-inflammatory, antipruritic, antiallergic, antiproliferative and vasoconstrictive a

相关文献及参考

  • [2]. Nishibe Y, et al. Species and sex differences in the inhibitory action of the corticosteroid alclometasone dipropionate on the hepatic drug-metabolizing system.Jpn J Pharmacol. 1989 Aug;50(4):435-43.
  • Aoyama, S. et al.: Drug Metab. Disp., 18, 409 (1990); Green, M.J. et al.: J. Steroid Biochem., 11, 61 (1979); De, K. et al.: J. Ind. Chem. Soc., 79, 513 (2002);
  • [1]. Alclometasone
  • [1]. Alclometasone
  • [2]. Nishibe Y, et al. Species and sex differences in the inhibitory action of the corticosteroid alclometasone dipropionate on the hepatic drug-metabolizing system.Jpn J Pharmacol. 1989 Aug;50(4):435-43.

系列性分类

  1. Medical Research Areas
  2. GPCR & G Protein
  3. Glucocorticoid Receptor  (糖皮质激素受体)

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