HEPES 4-羟乙基哌嗪乙磺酸

CAS 7365-45-9 MFCD00006158

化学结构图

7365-45-9
SMILES: O=S(=O)(O)CCN1CCN(CCO)CC1

化学属性

Mol. FormulaC8H18N2O4S
Mol. Weight238.30
Density1.07 g/mL at 20 °C
Melting Point234-238 °C
TSCAYes
Refractive indexn20/D 1.339
Solubility可溶
Appearance powder
Boiling Point408 °C at 760 mmHg

别名和识别编码

Chemical NameHEPES
Synonym HEPES {LY} HEPES {} {LY} HEPES {} {} {LY} HEPES {} {} {} {LY} HEPES {} {} {} {} {LY} HEPES {} {} {} {} {} {LY} HEPES {} {} {} {} {} {} {LY} HEPES {} {} {} {} {} {} {} {LY} HEPES {} {} {} {} {} {} {} {} {LY} HEPES {} {} {} {} {} {} {} {} {} {LY} HEPES {} {} {} {} {} {} {} {} {} {} {LY} HEPES {} {} {} {} {} {} {} {} {} {} {} {LY} HEPES {} {} {} {} {} {} {} {} {} {} {} {} {LY} HEPES {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} HEPES {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} HEPES {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} HEPES {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} HEPES {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} HEPES {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} HEPES {} {} {} {} {} {} {} {} {} {} {} {} {} {}
MDL NumberMFCD00006158
PubChem Substance ID23831
Beilstein Registry Number883043
CAS Number7365-45-9
Reaxys-RN883043
Merck Number4654
EC Number230-907-9
Chemical Name Translation4-羟乙基哌嗪乙磺酸
LabNetwork Molecule IDLN00194361
Canonical SMILESO=S(CCN1CCN(CCO)CC1)(O)=O
InChIInChI=1S/C8H18N2O4S/c11-7-5-9-1-3-10(4-2-9)6-8-15(12,13)14/h11H,1-8H2,(H,12,13,14)
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分类

  • {SNA} BioReagent Buffers, Biochemicals and Reagents, Biological Buffers, Buffer / Buffer Salts, Buffer Convenience Packaging, Buffer Solutions, Buffered Salt Solutions, Buffers / Buffer Salts, Buffers A to Z, Core Bioreagents, Good’s Buffers, Life Science Reagents for Cell Culture, Life Science Reagents for Cloning, Life Science Reagents for Northern and Southern Blotting, Life Science Reagents for PCR, Life Science Reagents for Protein Expression and Purification, Life Science Reagents for RNAi, Life Science Reagents for Transfection, Research Essentials
  • {SNA} Biological Buffers, Buffer Convenience Packaging, Buffer Solutions, Buffers A to Z,
  • {SNA} BioPerformance Certified Buffers,
  • {SNA

产品应用

  • 分子生物学级用于用T4 RNA连接酶进行RNA3' -末端标记，分离与分析核RNA之反应缓冲液组分、预杂交缓冲液缓和杂交缓冲液成分

相关文献及参考

  • Biological buffer, pKa = 7.55 at 20o: Biochemistry, 5, 467 (1966).

安全信息

WGK Germany1
Personal Protective Equipment Eyeshields, Gloves, half-mask respirator (US), multi-purpose combination respirator cartridge (US) Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
RTECSTL6809000
Signal word Warning
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛，皮肤或衣服。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P350
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P332+P313
  • P337+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
GHS Symbol
Safety Statements
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Hazard Codes Xi
Storage condition Store at room temperature {LY} Store at room temperature {} {LY} Store at room temperature {} {} {LY} Store at room temperature {} {} {} {LY} Store at room temperature {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} { 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - quail
DOSE/DURATION           : >316 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EESADV Ecotoxicology and Environmental Safety.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802)  V.1-    1977-  Volume(issue)/page/year:
   6,149,1982

其他信息

  • 用途一:生物缓冲剂
  • useful pH range 6.8 - 8.2
  • 海关编码:29335995
  • MSDS 信息:2-[4-(2-Hydroxyethyl)-1-piperazine]ethanesulfonic acid(7365-45-9).msds
  • Acros Organics:HEPES/N-（2-羟乙基）哌嗪-N'-乙烷磺酸 HEPESfreeacid,DNase,RnaseandProteasefree,formolecularbiology,99+%(7365-45-9)
  • 检测方法:T,NMR
  • Alfa Aesar:HEPES,99% HEPES, 99%(7365-45-9)
  • 图谱信息:4-羟乙基哌嗪乙磺酸(7365-45-9)红外图谱(IR1) 4-羟乙基哌嗪乙磺酸(7365-45-9)质谱(MS)
  • Sigma Aldrich:7365-45-9(sigmaaldrich)
  • useful pH range 6.8 - 8.2 pKa (25 °C) 7.5
  • 外观性质:白色结晶粉末。 密度：1.07pH range 6.8 - 8.2 pKa (25 °C) 7.5
  • TCI Shanghai:4-羟乙基哌嗪乙磺酸[生物研究用Good's缓冲液中的成分] 2-[4-(2-Hydroxyethyl)-1-piperazinyl]ethanesulfonic Acid [Good's buffer component for biological research],>;99.0%(T)(7365-45-9)
  • 用途二:生物缓冲液
  • MOL 文件:7365-45-9.mol
  • 4-羟乙基哌嗪乙磺酸价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 30101586 N-(2-羟乙基）哌嗪-N’-（2-乙烷磺酸） 25g 300元 2011/04/16 H0396 2-[4-(2-羟乙基)-1-哌嗪基]乙磺酸[生物研究用Good's缓冲液中的成分] 2-[4-(2-Hydroxyethyl)-1-piperazinyl]ethanesulfonic Acid [Good's buffer component for biological research] 25G 290元 2011/04/16 H0396 2-[4-(2-羟乙基)-1-哌嗪基]乙磺酸[生物研究用Good's缓冲液中的成分] 2-[4-(2-Hydroxyethyl)-1-piperazinyl]ethanesulfonic Acid [Good's buffer component for biological research] 500G 2510元

系列性分类

  1. Life Science 生命科学
  2. Biological Buffers 生理缓冲剂
  3. Buffers A to Z - Biological Buffers
  1. Life Science 生命科学
  2. Biological Buffers 生理缓冲剂
  3. BioUltra Buffers - Biological Buffers
  1. Life Science 生命科学
  2. Biological Buffers 生理缓冲剂
  3. Buffer Convenience Packaging - Biological Buffers
  4. Buffer Solutions - Buffer Convenience Packaging
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Luminescent Compounds/Detection - Biochemicals and Reagents
  4. Solvents, Buffers and Reagents for Luminescence - Luminescent Compounds/Detection
  1. Life Science 生命科学
  2. Biological Buffers 生理缓冲剂
  3. BioUltra Buffers - Biological Buffers
  4. Alphabetical - BioUltra Buffers
  1. Life Science 生命科学
  2. Molecular Biology 分子生物学
  3. Molecular Biology Reagents - Molecular Biology
  4. BioUltra - Molecular Biology Reagents
  1. Life Science 生命科学
  2. Cell Culture 细胞培养
  3. Specialty Media Systems - Cell Culture
  4. Embryo Culture - Specialty Media Systems
  5. Reagents and Media Supplements - Embryo Culture
  1. Life Science 生命科学
  2. Proteomics 蛋白质组学
  3. Protein Structural Analysis - Proteomics
  4. X-Ray Crystallography - Protein Structural Analysis
  5. Optimization Reagents - X-Ray Crystallography
  1. Research Essentials 基础科研
  2. Core Bioreagents - Research Essentials
  3. Life Science Reagents for Northern and Southern Blotting - Core Bioreagents
  4. Buffer / Buffer Salts 缓冲液/缓冲盐
  1. Research Essentials 基础科研
  2. Core Bioreagents - Research Essentials
  3. Life Science Reagents for Cell Culture - Core Bioreagents
  4. Buffered Salt Solutions - Life Science Reagents for Cell Culture
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Apoptosis and Cell Cycle - Cell Signaling and Neuroscience
  5. Other Apoptosis Related Reagents - Apoptosis and Cell Cycle
  6. Buffers - Other Apoptosis Related Reagents
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Heterocyclic Acids 杂环酸
  5. Piperazine Acids
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Cell Culture
  4. Specialty Media Systems
  5. Embryo Culture

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