C-8 Ceramide N-辛酰基-D-神经鞘氨醇
CAS 74713-59-0 MFCD00236496
化学结构图
SMILES: CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO)NC(=O)CCCCCCC
化学属性
| Mol. Formula | C26H51NO3 |
|---|---|
| Mol. Weight | 425.69 |
别名和识别编码
| Chemical Name | N-Octanoyl-D-sphingosine |
|---|---|
| CAS Number | 74713-59-0 |
| Synonym | ######## C8 ceramide |
| MDL Number | MFCD00236496 |
| PubChem Substance ID | 24897955 |
| Chemical Name Translation | N-辛酰基-D-神经鞘氨醇 |
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分类
- {SNA} Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Ceramides, Lipids, Lipids in Cell Signaling, Metabolic Pathways, Metabolomics, N-acylsphingosines (ceramides), O, Sphingolipid Metabolism,
- Bioactive Small Molecules,
产品应用
- A biologically active, cell permeable, but nonphysiologic ceramide analog. It induces phosphorylation on Thr-669 in A-431 cells by stimulation of ceramide-activated protein kinase. It stimulates IL-
相关文献及参考
- Mathias, S., et al.: Proc. Natl. Sci. USA, 88, 10009 (1991),
- Mathias, S., et al.: Science, 259, 519 (1993),
- Jarvis, W.D. et al., Induction of apoptotic DNA damage and cell death by activation of the sphingomyelin pathway. Proc. Natl. Acad. Sci. U. S. A. 91 , 73, (1994) 摘要
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