1,2-Dibromopropane 1,2-二溴丙烷

CAS 78-75-1 MFCD00000148

化学结构图

78-75-1
SMILES: CC(Br)CBr

化学属性

Mol. FormulaC3H6Br2
Mol. Weight201.89
Refractive index1.5170 to 1.5210
Boiling Point141°C
Density1.937 g/mL at 25 °C(lit.)
Melting Point-55 °C(lit.)
Flash Point50°C(lit.)
TSCAYes
Solubility略溶于水
pH:A

别名和识别编码

Chemical Name1,2-Dibromopropane
Synonym 1 1,2-Dibromopropane,97% 1,2-dibromo-propan 2-溴丙基溴 1,2-Dibromopropane98% (RS)-Dibrompropan 二溴化丙烯;2-溴丙基溴 二溴化丙烯 (±)-1,2-Dibromopropane propane, 1,2-dibromo- 1,2-Dobromopropane 1,2-Dibrompropan 2-Bromopropylbromide 1,2-Dibromopropane 2,3-Dibromopropane (±)-1,2-dibromo-propane 11,2-DIBROMOPROPANE PROPYLENE DIBROMIDE CH2BrCHBrCH3 PROPYLENE BROMIDE 1,2 - Propylene Dibromide Propylene dibromide 1,2-二溴丙烷 1,2-dibromopropane Propylenbromid Propane,1,2-dibromo- 1,2-DIBROMOPROPANE Propylendibromid propylene dibromide 二溴丙烷 2,3-dibromopropane 2-二溴丙烷 溴化丙烯 1,2-二溴丙烷 1,2-二溴丙烷, 98% 1,2-Propylenebromide
MDL NumberMFCD00000148
CAS Number78-75-1
PubChem Substance ID87566917
EC Number201-139-1
Beilstein Registry Number1,109
Merck Number7853
Reaxys-RN1718884
Chemical Name Translation1,2-二溴丙烷
Wiswesser Line NotationEY1&1E
LabNetwork Molecule IDLN01741316
InChIInChI=1S/C3H6Br2/c1-3(5)2-4/h3H,2H2,1H3
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分类

  • {uni_hamburg} no charge; racemate; 1fragment
  • {SNA} Alkyl, Building Blocks, Chemical Synthesis, Halogenated Hydrocarbons, Organic Building Blocks

产品应用

  • 用作有机合成原料、化学试剂及溶剂。

相关文献及参考

  • Short: II/25C
  • Merck: 14,7853 Beilstein:1,109
  • Short: II/5
  • Merck: 14,7853
  • Short: III/38A

安全信息

GHS Symbol
WGK Germany3
Hazard statements
  • H226 Flammable liquid and vapour 易燃液体和蒸气
  • H302 Harmful if swallowed 吞食有害
  • H302+H332
  • H332 Harmful if inhaled 吸入有害
Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
RTECSTX8574000
Signal word Warning
Packing GroupIII
UN Number 1993 UN 1993 3/PG 3 UN1993
Risk Statements
  • R20/22 Harmful by inhalation and if swallowed 吸入和不慎吞咽有害
  • R10 Flammable 易燃
  • R36/38 Irritating to eyes and skin 对眼睛和皮肤有刺激性
  • R51/53
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
Safety Statements
  • S9 Keep container in a well-ventilated place 保持容器在通风良好的场所;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S57 Use appropriate containment to avoid environmental contamination 使用适当容器避免环境污染;
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
  • S23 Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) 不要吸入气体/烟雾/蒸汽/喷雾;
  • S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
Hazard Codes Xn
Precautionary statements
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P233 Keep container tightly closed. ?保持容器密闭。
  • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
  • P241+P242+P243
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P312+P330
  • P302+P352+P332+P313+P362+P364
  • P305+P351+P338+P337+P313
  • P332+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P403+P235
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard Class3
Storage condition Flammables area 充氩保存
Warnings 危化品目录(2015)
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 676 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 41(3),105,1976

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 75 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: AD691-490

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 741 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 41(3),105,1976

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 12 gm/m3/4H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single
   Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects,
   GKNT, 1982  Volume(issue)/page/year: -,43,1982

TYPE OF TEST            : Sex chromosome loss and nondisjunction
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Insect - Drosophila melanogaster
DOSE/DURATION           : 5 mmol/L
REFERENCE :
   EXPEAM Experientia.  (Birkhaeuser Verlag, POB 133, CH-4010 Basel,
   Switzerland)  V.1-    1945-  Volume(issue)/page/year: 30,621,1974

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 10 umol/plate
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 2,59,1980

TYPE OF TEST            : DNA damage
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 75716 ug/kg
REFERENCE :
   CRTOEC Chemical Research in Toxicology.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB 57/36, West End Station, Washington, DC
   20037)  V.1-    1988-  Volume(issue)/page/year: 4,528,1991

Restrict 危险品

其他信息

  • 毒性分级:中毒
  • Alfa Aesar:1,2-二溴丙烷,98% 1,2-Dibromopropane, 98%(78-75-1)
  • 下游产品:1,3-丙二胺 --> 戊二腈
  • 灭火剂:泡沫, 干粉, 1211灭火剂
  • 类别:有毒物品
  • 可燃性危险特性:可燃, 火场排出含溴化物辛辣刺激烟雾
  • 上游原料:无水氯化钙
  • Sigma Aldrich:78-75-1(sigmaaldrich)
  • 职业标准:STEL 5 毫克/ 立方米
  • 急性毒性:口服- 大鼠 LD50: 741 毫克/ 公斤; 口服- 小鼠 LD50: 676 毫克/ 公斤
  • 1,2-二溴丙烷价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/04/16 D0203 1,2-二溴丙烷 1,2-Dibromopropane 500G 1160元 2011/04/16 D0203 1,2-二溴丙烷 1,2-Dibromopropane 25G 190元 2010/06/21 161370050 1,2-二溴丙烷 1,2-Dibromopropane 99% 5 ML 233元
  • Acros Organics:1,2-二溴丙烷 1,2-Dibromopropane, 99%(78-75-1)
  • 储运特性:库房通风低温干燥; 与食品、氧化剂、酸类分开储运
  • 用途一:用作有机合成中间体
  • TCI Shanghai:1,2-二溴丙烷 1,2-Dibromopropane,>;98.0%(GC)(78-75-1)
  • 方法一:1.丙烯直接溴化可得1,2-二溴丙烷。2.由溴丙烷经溴化而得先将溴丙烷与铁粉混合,加热至40-50℃,慢慢加入溴素,加完后继续回流2h。然后,滤除铁渣,滤液用水洗几次,5%碳酸钠溶液洗一次,再用5%硫代硫酸钠溶液洗除游离溴。以无水氯化钙干燥。分馏,收集139-142℃馏分即为成品。3.丙醇溴化法。
  • 图谱信息:1,2-二溴丙烷(78-75-1)红外图谱(IR1) 1,2-二溴丙烷(78-75-1)核磁图( 13 CNMR) 1,2-二溴丙烷(78-75-1)质谱(MS) 1,2-二溴丙烷(78-75-1)核磁图( 1 HNMR) 1,2-二溴丙烷(78-75-1)Raman光谱
  • MOL 文件:78-75-1.mol
  • 海关编码:29033036
  • 能与乙醇、乙醚、丙酮和氯仿混溶。水中溶解度25℃时0.2%,80℃时0.3%,受高温时能分解放出毒气。
  • 外观性质:无色液体。
  • 用途三:用作有机合成原料、化学试剂及溶剂。
  • 1,2-二溴丙烷价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 D0203 1,2-二溴丙烷 1,2-Dibromopropane 500G 1690元 2014/06/02 D0203 1,2-二溴丙烷 1,2-Dibromopropane 25G 303元 2010/06/21 161370050 1,2-二溴丙烷 1,2-Dibromopropane 99% 5 ML 233元
  • MSDS 信息:1,2-二溴丙烷(78-75-1).msds
  • 用途二:用于有机合成,也用作溶剂

系列性分类


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